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Auxilium Pharmaceuticals Announces Additional Data from Three-Year XIAFLEX® Recurrence Study in Dupuytren's Contracture in E-poster at ASSH Meeting
Date:9/8/2011

ere evaluable. In the 71% of patients with MP joints that achieved clinical success and did not recur through three years, the mean degree of contracture was 37.6 degrees at pre-treatment baseline and 2.8 degrees at three years. In the 21% of MP joints that achieved clinical success and did recur through three years, the mean degree of contracture was 40.1 degrees at pre-treatment baseline and 36.7 degrees at three years. Eight percent of patients with MP joints received medical or surgical intervention and were therefore not included in this analysis. Similar trends were seen through three years with evaluable patients with Proximal Interphalangeal (PIP) joints that achieved clinical success.

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These data will be available starting September 8 via an e-poster from Dr. Thomas Kaplan et al. that is entitled "Year 3 recurrence data for the use of CCH in the treatment of Dupuytren's Contracture with a palpable cord." E-posters will be available during the entire ASSH meeting via the kiosks in the meeting hall or online at http://tinyurl.com/AM11eposters. A complete analysis of the three-year recurrence data is pending and the Company is seeking publication of full results in an appropriate medical journal.

About Dupuytren's contracture

Dupuytren's contracture is a chronic condition that affects the connective tissue that lies beneath the skin in the palm. The disease is progressive in nature. Typically, skin pits then nodules develop in the palm as collagen deposits accumulate. As the disease progresses, the collagen deposits form a cord that stretches from the palm of the hand to the base of the finger. Once this cord develops, the patient's fingers contract and the function of the hand is impaired. The incidence of Dupuytren's disease, inclusive of pits, nodules a
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SOURCE Auxilium Pharmaceuticals, Inc.
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