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Auxilium Pharmaceuticals, Inc. and BioSpecifics Technologies Corp. Announce Plans to Develop Additional Indications using XIAFLEX®
Date:8/31/2011

ges under the epidermis around the dimple that can give skin a "cottage cheese" texture.

Cellulite has been reported to occur in 85 to 98% of post-pubertal females and rarely in men.  The condition is prevalent in women of all races.(1)  

(1) Avram, Cellulite: a review of its physiology and treatment, Journal of Cosmetic Laser Therapy 2004; 6: 181–185

(2) Querleux, Anatomy and physiology of subcutaneous adipose tissue by in vivo MRI and spectroscopy: Relationship with sex and presence of cellulite, Skin Research and Technology; 8: 118-124

About Human and Canine LipomaLipomas are encapsulated fat deposits that occur under the skin and they are common in both humans and dogs. Approximately 1% of the general human population has a lipoma.(1) Subcutaneous lipomas are the most common lipomas found in humans.

In addition, lipomas that restrict motion in older dogs are a serious problem. The only proven therapy for this condition is surgical excision of the lipoma, which necessarily involves the use of general anesthesia. It has been estimated that up to 2% of dogs die as a complication of general anesthesia.(2) Lipomas occur in 2.3% of the dog population,(3) or in approximately 1.7 million dogs in the U.S.(4)

(1) Nickloes  E-Medicine 2010 March

(2) Brodbelt Vet J 2009 Dec; 182 (3): 375-6

(3) Lund JAVMA Vol. 214, No. 9, May 1, 1999

(4) U.S. Pet Ownership & Demographics Sourcebook (2007 Edition)

AUXILIUM SAFE HARBOR STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995This release contains "forward-looking-statements" within the meaning of The Private Securities Litigation Reform Act of 1995, including statements regarding the timing of phase Ib clinical studies for XIALFEX® for the treatment of edematous fibrosclerotic panniculopathy, more commonly known as cellulite; the number of people with cellulite; the identification of additional
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SOURCE Auxilium Pharmaceuticals, Inc.
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