Navigation Links
Auxilium Pharmaceuticals, Inc. Announces Positive Top-Line Results from XIAFLEX® Multi-Cord Study
Date:9/7/2011

MALVERN, Pa., Sept. 7, 2011 /PRNewswire/ -- Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL), a specialty biopharmaceutical company, today announced positive top-line results from a pilot clinical study to assess safety, tolerability, and multiple-dose pharmacokinetics of XIAFLEX® (collagenase clostridium histolyticum) in adult Dupuytren's contracture subjects with multiple  palpable cords.  The tolerability profile following concurrent injection of two doses of XIAFLEX into palpable cords in the same hand is consistent with that demonstrated in pivotal clinical trials following a XIAFLEX injection into a single palpable cord.  

(Logo: http://photos.prnewswire.com/prnh/20101202/MM10881LOGO)

"We were encouraged that multiple injections of XIAFLEX into the same hand concurrently have demonstrated a preliminary tolerability profile clinically similar to that of a single injection," said Dr. James P. Tursi, Chief Medical Officer at Auxilium.   "Concurrent multiple injections of XIAFLEX would offer hand surgeons the ability to treat several joints in the same hand at the same time, which would be similar to historical surgical interventions."  

In this phase IIIb study, 12 adult subjects with 36 palpable cords were enrolled at a single site in Australia.  All subjects were required to have Dupuytren's disease with at least three fixed-flexion contractures, excluding the thumb.  Each subject was given a single injection of XIAFLEX and, if no severe local or systemic reaction was observed, concurrent injections of two doses of XIAFLEX were given into two palpable cords in the same hand.   In the pivotal phase III clinical trials, only a single joint was treated with XIAFLEX and additional joints were required to be treated sequentially every 30 days.  Following the multiple concurrent injections in the pilot study, patient
'/>"/>

SOURCE Auxilium Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Auxilium Pharmaceuticals, Inc. and BioSpecifics Technologies Corp. Announce Plans to Develop Additional Indications using XIAFLEX®
2. Auxilium Pharmaceuticals Announces Investor Event to Occur at 2011 ASSH Meeting on September 9, 2011
3. Auxilium Pharmaceuticals to Present at the Stifel Nicolaus 2011 Healthcare Conference
4. Auxilium Pharmaceuticals, Inc. Announces Promotion of Dr. James P. Tursi to Chief Medical Officer
5. Auxilium Pharmaceuticals to Announce Second Quarter 2011 Results and Conduct Conference Call on Monday, August 1, 2011
6. Auxilium Pharmaceuticals Announces Results from Three Year CORDLESS Extension Study in Dupuytrens Contracture
7. Auxilium Pharmaceuticals to Present at the Bank of America Merrill Lynch 2011 Health Care Conference
8. Auxilium Pharmaceuticals to Present at the Deutsche Bank 36th Annual Health Care Conference
9. Auxilium Pharmaceuticals, Inc. Announces Launch of XIAPEX® in EU by Pfizer
10. Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan
11. Auxilium Pharmaceuticals, Inc. Completes Enrollment of XIAFLEX® Phase III Double-Blind Studies for Peyronies Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... HARRISBURG, Pa. , Dec. 19, 2014 ... a routine checkup and cleaning when he or she ... term you,ve probably heard before, you may have several ... You,ll be relieved to know it,s nothing to ... help answer patients, questions and alleviate any anxiety the ...
(Date:12/19/2014)... HILL, N.C. , Dec. 19, 2014 /PRNewswire/ ... to optimize a product,s web presence to reflect ... Brand websites, in particular, must meet the needs ... regulations and culture. According to ... more than half of the participating companies averaged ...
(Date:12/19/2014)... Texas , December 18, 2014 ... networked software application/module that is used to store, ... images. RIS comprises a patient tracking and scheduling ... The integration of RIS with HIS and other ... for patient registration and patient scheduling, patient list ...
Breaking Medicine Technology:Root Canals Have Become More Routine 2Building a Best-in-Class Pharma Global Brand Website 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3
... Inc. today announced that Ho Cho, Ph.D., the company,s ... company,s antibody drug conjugate (ADC) programs at five upcoming ... recent xenograft studies comparing Ambrx ADCs with those created ... been clinically validated as safe and efficacious for creating ...
... YORK, June 22, 2011 (Digital Experience!) -- iHealth ... personal healthcare products including the iHealth BP3 Blood Pressure ... announced that multiple national retail chains will now distribute ... Pressure Monitoring System is now available in all Apple ...
Cached Medicine Technology:Ambrx to Present Data from Antibody Drug Conjugate Program at Upcoming Scientific Conferences 2iHealth Lab's Blood Pressure Self-Monitoring System Gets Nationwide Distribution 2
(Date:12/20/2014)... Twin Cities DI Day is recognized as the premier ... financial professionals come together each year to hear up ... to protect their clients and to be inspired by ... of disability. , On September 23rd, 2014, financial professionals ... The 13th Annual Twin Cities DI Day where they ...
(Date:12/19/2014)... 2014 Sweetdressy.com , a leading ... its newest selection of cheap prom dresses for ladies ... in the world and clients can buy these dresses ... prom dresses feature cool cuts and delicate craftsmanship, and ... the middle-end market. Discount shipping costs are available for ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 SuperCloset raises ... SuperClone Rooms. SuperCloset continues to offer indoor growers the ... one of the new SuperClone Rooms with the award ... and turnkey indoor hydroponic grow room setup. , The ... world, SuperCloset’s SuperPonic SuperCloner 50 . ...
(Date:12/19/2014)... 2014 The print component of Vision ... subscription of the Toronto Star, with a circulation of ... The digital component is distributed nationally through a vast ... news sites and partner outlets. To explore the digital ... The publication features an exclusive interview with Mark ...
(Date:12/19/2014)... FRIDAY, Dec. 19, 2014 (HealthDay News) -- Injectable drug ... double the suicide attempt rate of other substance users, ... use is associated with the risk of suicide attempt ... the University of Montreal, said in a university news ... users. We wanted to know who among substance users ...
Breaking Medicine News(10 mins):Health News:The 13th Annual Twin Cities DI Day Now On Video 2Health News:The 13th Annual Twin Cities DI Day Now On Video 3Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2Health News:Mark DeMontis, Founder of Courage Canada, shares his passion for bringing hockey to those affected by blindness in Mediaplanet’s “Vision and Hearing” campaign 2Health News:Cocaine, Amphetamines May Up Injection Drug Users' Suicide Risk 2
... in the supercomputer MareNostrum at the Barcelona Supercomputing Center, ... Research in Biomedicine (IRB Barcelona) have presented the world,s ... new database holds more than 1,700 proteins and is ... been developed to study the basic biology of proteins ...
... brain structure known as the amygdala. It is the amygdala ... and not only triggers palpitations or nausea but can also ... been known about the function of this part of the ... develops, and which of the countless neurons in the amygdaloid ...
... News) -- Middle-aged couples with good "numeracy" skills are wealthier ... Numeracy -- the ability to reason with numbers and ... learned in school, according to the RAND Corporation researchers who ... the U.S. Health and Retirement Survey. The investigators found ...
... WEDNESDAY, Nov. 10 (HealthDay News) -- Offering your baby ... protection against the development of the antibodies associated with type ... disease, new research suggests. When Finnish researchers randomly ... to receive either a regular infant formula, or one that ...
... prostate cancer may have an increased risk of colorectal ... in The Journal of the National Cancer Institute. ... treatment in men with prostate cancer, although its usage ... effects, including osteoporosis, cardiovascular disease, diabetes and obesity; the ...
... the American Society of Nephrology (ASN) proudly highlight ... by The Halpin Foundation-ASN Research Grant, created to ... award provides recipients transition funding toward successful application ... PhD (McGill University Faculty of Medicine), the 2008 ...
Cached Medicine News:Health News:Scientists at IRB Barcelona and BSC publish the world's largest video data bank of proteins 2Health News:Circuitry of fear identified 2Health News:Math Skills Boost Couples' Financial Worth: Study 2Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 2Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 3Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 4Health News:Colorectal cancer risk increases in prostate cancer patients on androgen deprivation therapy 2Health News:Putting the spotlight on membranous nephropathy 2
... Rotanta 460 family of ... line that meets a ... They feature high capacity, ... state-of-the-art technology and high ...
... Five models to choose fromTabletops ... refrigeration. Features of the Spinchron DLX ... Smooth, maintenancefree operation with a brushless ... acceleration and deceleration rates; Continuous or ...
The Spinchron 15 centrifuge provides all the versatility and high capacity needed for today's full-service clinical lab needs. This centrifuge is available in a nonrefrigerated model with a speed up ...
... CKX microscopes utilize the infinity-corrected ... and operability in cell checking. ... inverted microscope suited to routine ... fields--from tissue culture and embryology ...
Medicine Products: