Navigation Links
Authorization for AGENDA Phase 3 Trial of Genasense(R) in Advanced Melanoma Granted by French Regulatory Agency
Date:10/17/2007

Decision Facilitates European Trial Opening in 13 New Sites

BERKELEY HEIGHTS, N.J., Oct. 17 /PRNewswire-FirstCall/ -- Genta Incorporated (Nasdaq: GNTA) announced that the French Health Products Safety Agency ("AFSSAPS") has granted authorization to open the Company's Phase 3 trial of Genasense(R) (oblimersen sodium) Injection, its lead anticancer compound, in patients with advanced melanoma. This authorization enables the opening of approximately 13 new investigative sites over the next 2-4 weeks.

Genta's Phase 3 trial, known as AGENDA, is a randomized, double-blind, placebo-controlled study in which patients are randomly assigned to receive Genasense plus dacarbazine (DTIC) or DTIC alone. AGENDA will accrue approximately 300 patients and will be conducted at approximately 100 sites worldwide, including North America, Europe and Australia. Accrual, which is currently ongoing, is currently expected to complete in the fourth quarter of 2008.

About Genasense

Genasense inhibits production of Bcl-2, a protein made by cancer cells that is thought to block chemotherapy-induced apoptosis (programmed cell death). By reducing the amount of Bcl-2 in cancer cells, Genasense may enhance the effectiveness of current anticancer treatment. Genta is pursuing a broad clinical development program with Genasense evaluating its potential to treat various forms of cancer.

About Genta

Genta Incorporated is a biopharmaceutical company with a diversified product portfolio that is focused on delivering innovative products for the treatment of patients with cancer. The Company's research platform is anchored by two major programs: DNA/RNA-based Medicines and Small Molecules. Genasense(R) (oblimersen sodi
'/>"/>

SOURCE Genta Incorporated
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
7. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... and TARRYTOWN, N.Y. , May 21, ... and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that ... online the positive Phase 2a study results of dupilumab ... an investigational monoclonal antibody targeting the alpha subunit of ... of both IL-4 and IL-13, drivers of Th2 (Type ...
(Date:5/21/2013)... Calif. , May 21, 2013 Abaxis, ... blood analysis systems, announced today that Martin ... at the Stifel Annual Dental & Veterinary Conference on ... conference will be held at Le Parker Meridien Hotel ... About Abaxis Abaxis develops, manufactures, markets ...
(Date:5/21/2013)... 2013 Reportlinker.com announces that a ... its catalogue:   ... Medical Devices in the US Market ... Changing Regulatory and Reimbursement Scenario for ...   Summary ...
Breaking Medicine Technology:Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 2Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 3Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 4Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 5Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 6Sanofi and Regeneron Announce Publication of Positive Phase 2a Results of Dupilumab in Asthma in the New England Journal of Medicine 7Abaxis, Inc. to Present at the Stifel Annual Dental & Veterinary Conference 2Changing Regulatory and Reimbursement Scenario for Medical Devices in the US Market 2Changing Regulatory and Reimbursement Scenario for Medical Devices in the US Market 3Changing Regulatory and Reimbursement Scenario for Medical Devices in the US Market 4
... FARMINGTON, Conn., May 9, 2012 /PRNewswire-iReach/ -- ... new reports tracking the growth in the patient monitoring ... Devices, Players, Markets and Forecasts The convergence of ... initiatives is driving patient monitoring away from caregiver facilities ...
... Medical Outsourcing announced today that the company hired ... As a seasoned quality specialist with 18 years ... the quality systems for all of Millstone Medical,s ... with customers to ensure the highest quality standards. ...
Cached Medicine Technology:New Forecast Shows Patient Monitoring Systems Market to Reach $18.9 billion by 2016 2New Forecast Shows Patient Monitoring Systems Market to Reach $18.9 billion by 2016 3Millstone Medical Outsourcing Hires New Vice President Quality 2
(Date:5/21/2013)... New York, New York (PRWEB) May 21, 2013 ... da Vinci surgery robot lawsuit is nearing its ... According to Bloomberg.com, during closing statements yesterday, an ... car dealership, alleging the company wanted to tie sales ... to do all the training to keep control of ...
(Date:5/21/2013)... Harbor, Florida (PRWEB) May 21, 2013 ... agency, announced today that they have redesigned their website ... a nude beach, pool, hot tubs, bars and dining. ... this nudist resort including sales and guest reviews, will ... island of Jamaica itself, including pages on culinary local ...
(Date:5/21/2013)... 2013 While North Carolina is synonymous ... travel guides. Brunswick Plantation & Golf Resort is synonymous ... access to 27 holes of "Top10" championship golf. ... Carolina, knowing the Top 10 from an ... the overwhelming task of selecting the course to play. ...
(Date:5/21/2013)... (PRWEB) May 22, 2013 About one ... the Fertility Clinics industry one of the ... assists patients who are unable to conceive naturally through ... popular of which is in-vitro fertilisation (IVF) cycles. Over ... cycles in Australia has increased by 4.4% per annum ...
(Date:5/21/2013)... HealthDay Reporter , , TUESDAY, May 21 (HealthDay News) -- ... sleep apnea in children, and while removing them did ... it did help them with sleep, behavior and quality ... is a condition that causes abnormal pauses in breathing ... sleep with the surgery, and those improvements were likely ...
Breaking Medicine News(10 mins):Health News:Da Vinci Surgery Robot Lawsuit News: Bernstein Liebhard LLP Comments on Closing Arguments in Nation’s First Da Vinci Lawsuit Trial 2Health News:Da Vinci Surgery Robot Lawsuit News: Bernstein Liebhard LLP Comments on Closing Arguments in Nation’s First Da Vinci Lawsuit Trial 3Health News:Da Vinci Surgery Robot Lawsuit News: Bernstein Liebhard LLP Comments on Closing Arguments in Nation’s First Da Vinci Lawsuit Trial 4Health News:The Oldest and Original Nudist Travel Agency for NResort Announced Today a Redesigned Website Featuring Information on Culinary Events, Flora and Fauna, and Photography 2Health News:Brunswick Plantation & Golf Resort Named in Top 10 Golf Resorts in North Carolina 2Health News:Fertility Clinics in Australia Industry Market Research Report Now Available from IBISWorld 2Health News:Fertility Clinics in Australia Industry Market Research Report Now Available from IBISWorld 3Health News:Removing Tonsils Helps Kids With Sleep Apnea, Study Finds 2Health News:Removing Tonsils Helps Kids With Sleep Apnea, Study Finds 3
... ANN ARBOR, Mich. Some patients with large tumors on ... and radiation over surgery to remove the voice box. ... Center found that a single round of chemotherapy could identify ... "Organ preservation studies have excluded these patients because their tumors ...
... a lump is found in the breast of an adolescent ... breast cancer is rare in adolescents, and the vast majority ... that are related to hormones. A recent Loyola University ... Roentgenology suggests that a breast ultrasound examination might eliminate ...
... Texas, June 25 Leading business and health care ... the Texas Coalition for Worksite Wellness, "Call for Coverage ... provide employees with comprehensive smoking cessation benefits. The ... with comprehensive smoking cessation coverage by an additional 100,000 ...
... State and Federal Healthcare Policy and Regulatory Team , ... of the largest law firms in Florida and one ... today the expansion of its Healthcare practice with significant ... healthcare professionals have joined the practice in the firm,s ...
... is available in German . , ... requires time- and labor-intensive molecular-biological procedures. Established methods are ... burden is very low, for example during a phase ... types of micro-pumps without movable parts, scientists from the ...
... Health Plan One of 17 Platinum-Level Award winners , ... Plan have been honored by the National Business Group on ... innovative programs that promote a healthy workplace and for helping ... their own health and well-being. , , UPMC was ...
Cached Medicine News:Health News:U-M study finds voice box can be preserved, even with the largest cancers 2Health News:What should a teenage girl do if she finds a lump in her breast? 2Health News:Business, Health Care Leaders Call on Texas Employers to Cover Smoking Cessation Benefits for an Additional 100,000 People by 2010 2Health News:Business, Health Care Leaders Call on Texas Employers to Cover Smoking Cessation Benefits for an Additional 100,000 People by 2010 3Health News:Akerman Senterfitt Announces Expansion of Healthcare Practice 2Health News:Akerman Senterfitt Announces Expansion of Healthcare Practice 3Health News:Virus filters for medical diagnosis 2Health News:UPMC and UPMC Health Plan Recognized by National Business Group on Health As a Leading Employer Promoting Healthy Lifestyles for Its Employees 2Health News:UPMC and UPMC Health Plan Recognized by National Business Group on Health As a Leading Employer Promoting Healthy Lifestyles for Its Employees 3
EZ-PSA is a one-step immunoassay for the rapid, qualitative determination of human Prostate Specific Antigen (PSA) in whole blood. The test is intended for professional use as an aid in the diagnosis...
Rapid Tumor Marker Test: Prostate Specific Antigen...
Remote Control Vision Tester Can Administer Basic,Distance Vision Tests in Less Than 2 Minutes....
... Quality of Vision and Contrast Sensitivity. ... illumination and glare luminance levels for ... testing with/without glare and background luminance ... ANSI standards. All Light Levels Microprocessor ...
Medicine Products: