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Atrium Medical Announces 1-year results of the INFUSE-AMI Trial
Date:5/3/2013

HUDSON, N.H., May 3, 2013 /PRNewswire/ -- Atrium Medical Corporation, a business unit of MAQUET Cardiovascular, today announced the 1-year results of the INFUSE-AMI (Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction) trial. Dr. Gregg Stone , the principle investigator, presented the exciting findings at the 62nd Annual American College of Cardiology Conference in San Francisco, CA.

INFUSE-AMI's primary endpoint was reduction in infarct size (also known as the size of the heart muscle impacted by a heart attack) measured by the highly sensitive cMRI, at 30-days in patients who were treated with intra-lesional ClearWay™ RX /abciximab* versus those that did not receive intra-lesional ClearWay RX/ abciximab. 

At 30-days, the primary endpoint was achieved, and patients who were treated with intra-lesional ClearWay RX/abciximab experienced a statistically significant relative reduction in infarct size of 16%.  Additionally, patients in the ClearWay RX /abciximab arm showed a favorable trend in new onset of severe heart failure in comparison to those patients that did not receive this treatment.

Clinical findings between 30-days and 1-year for patients who received intra-lesional ClearWay RX/abciximab were strongly associated with better outcomes, including significantly lower mortality rates and reduced major adverse cardiac and cerebral events compared to patients who did not receive ClearWay RX/abciximab.

Researchers also observed all mortality occurred in patients with an infarct size greater than 17.1%** (the median infarct size in the INFUSE-AMI trial was 17.2%).  The median infarct size for patients treated with ClearWay RX/abciximab was 15.1%, whereas the median infarct size for patients who received an alternative treatment was 17.9%. The INFUSE-AMI data shows a relationshi
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SOURCE Atrium Medical Corporation
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