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Atrium Announces the Publication of the COBEST Trial by the Journal of Vascular Surgery
Date:9/29/2011

months compared to BMS.  

In this study, Atrium's Vascular V12 has demonstrated higher long term patency and improved clinical outcomes compared to BMS.  COBEST was an independent investigator initiated study; Atrium Medical had no role in the study design, data collection, data interpretation, or writing of the clinical report.  Atrium provided funding for the study, including the employment of a research assistant.

Dr. Mwipatayi has provided this statement regarding COBEST: "This was the first prospective, randomized, multi center, controlled trial comparing balloon expandable covered stents directly to bare metal stents.  One striking result from the COBEST study was the 5 times lower TVR rate with Atrium's V12 compared to BMS.  This poses a tremendous global economic benefit along with a tremendous quality of life benefit for our patients who are being treated for peripheral vascular disease and more specifically aorto-iliac disease."

About Atrium's Advanta™ V12 covered stent

The Advanta™ Vascular V12 covered stent is a low profile, pre-mounted covered stent made of a radial expandable stainless steel that is completely encapsulated with Atrium's patented one-piece covering technology.  Atrium's patented covering technology creates a thermoconformable microporous PTFE layer that completely encapsulates the stainless steel stent.

Covered stents have been shown to exclude plaque and endothelium, thereby potentially mitigating late luminal loss by halting migration and proliferation of vascular smooth muscle cells and inflammatory cells through open stent struts thus leading to a reduction in restenosis and occlusion rates.  With over 125 clinical publications and over 100,000 patients successfully treated worldwide, this latest publication adds to the rapidly growing body of evidence supporting the safety and efficacy of Atrium's covered stent technology.  The V12 covere
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SOURCE Atrium Medical Corporation
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