Navigation Links
At One Month Post-Launch, Nearly a Quarter of Surveyed U.S. Oncologists Have Prescribed Tafinlar for Malignant Melanoma, Compared to 15 Percent Who Used Mekinist
Date:10/22/2013

EXTON, Pa., Oct. 22, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that at one month post-launch, approximately one-quarter of surveyed U.S. medical oncologists have prescribed GlaxoSmithKline's BRAF-inhibitor Tafinlar for malignant melanoma, compared with 15 percent who report having prescribed GlaxoSmithKline's MEK inhibitor, Mekinist.

(Logo:  http://photos.prnewswire.com/prnh/20130103/MM36805LOGO )

According to the first wave of the LaunchTrends® Tafinlar/Mekinist report series, the inability to differentiate between Tafinlar and Mekinist from Roche/Genentech/Daiichi Sankyo's first-to-market BRAF-inhibitor Zelboraf is the greatest constrainer of medical oncologists' prescribing of these new market entrants. While use of Tafinlar and Mekinist in combination is not FDA-approved, surveyed oncologists believe combination therapy may represent the ultimate strategy for treating BRAF-mutated unresectable/metastatic malignant melanoma and provide the optimal platform for differentiation from Zelboraf.

The report also finds that approximately half of all surveyed U.S. medical oncologists are highly willing to prescribe Tafinlar and Mekinist as monotherapies, with more than three-quarters of nonprescribers reporting that they intend to prescribe Tafinlar and Mekinist within the next six months. For first-line BRAF-mutated unresectable/metastatic malignant melanoma, the highest percentage of surveyed U.S. medical oncologists indicated that they would prescribe Tafinlar in patients with brain metastases, whereas the highest percentage of surveyed U.S. medical oncologists reported they would be most likely to prescribe Mekinist in patients harboring the BRAF V600K mutation.

"Interestingly, almost 50 percent of surveyed U.S. medical oncologists indicated they would prescribe Tafinlar or Mekinist in BRAF-mutated unresectable/metastatic malignant melanoma in patients who had progressed on a first-line of Zelboraf," said Decision Resources Group Senior Business Insights Analyst Karen Pomeranz, M.Sc., Ph.D. "This use of Tafinlar and Mekinist arises despite only provisional evidence to suggest Tafinlar exhibits efficacy following treatment with Zelboraf. Moreover, Mekinist is specifically not indicated for treatment of patients who have progressed on prior BRAF-inhibitor therapy."

About BioTrends Research Group
BioTrends Research Group provides syndicated and custom primary market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please visit www.bio-trends.com. BioTrends is a Decision Resources Group company.

About Decision Resources Group
Decision Resources Group is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources Group at www.DecisionResourcesGroup.com.

All company, brand, or product names contained in this document may be trademarks of their respective holders.

For more information, contact:

Decision Resources Group
Christopher Comfort
781-993-2597
ccomfort@dresources.com

 


'/>"/>
SOURCE BioTrends Research Group
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Hologic to Mark Start of Breast Cancer Awareness Month with NASDAQ Opening Bell Ceremony
2. At One Month Post-Launch, Nearly One-Quarter of Surveyed U.S. Medical Oncologists Have Prescribed Xofigo to Their Prostate Cancer Patients
3. Tecfideras Patient Share at Three Months Postlaunch Surpasses That for Aubagio and Gilenya At the Same Stage of Their Launches
4. Users of PediaVisions Spot Vision Screener Honor Childrens Eye Health and Safety Month with Back-to-School Screenings
5. International Isotopes Inc. Announces Second Quarter and Six Months 2013 Financial Results
6. One in Four Surveyed EU5 Physicians Has Been Required to Change a Prescription for Some or Most of Their HIV Patients in the Past Twelve Months, Primarily to Reduce Costs
7. For Multiple Sclerosis Treatment, Prescriber Base for Genzymes Aubagio Among U.S. Neurologists Has Increased Significantly at Six Months Post-launch, Compared to One and Three Months Post-launch
8. InspireMDs MGuard Embolic Protection Stent (EPS) Shows Lower Mortality Rate in STEMI Patients at Six Months Compared to Control Group
9. ALK Partners with AAFA to Launch New Online Resource for Allergic Patients During Allergy & Asthma Awareness Month
10. Pro-Dex, Inc. Announces Fiscal Third Quarter And Nine-Month Results
11. Addressing Hearing Loss Proves Win-Win for Both Employer and Employee, BHI Advises During National Employee Wellness Month
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Tenn. , Feb. 8, 2016  A research ... scientists has discovered details of how the abnormal ... triggers a particularly aggressive form of acute lymphoblastic leukemia ... in which genetic mutations trigger overproduction of immature cells, ... The discoveries of the malfunction underlying the type ...
(Date:2/8/2016)... SAN DIEGO , Feb. 8, 2016 /PRNewswire/--  ... have announced that advanced tissue-engineering services are now ... using a groundbreaking new three-dimensional (3D) bioprinting approach ... Regenova® 3D Bio Printer , a state-of-the-art robotic ... Applications has created a powerful pay-for-service bio-printing model ...
(Date:2/8/2016)... Feb. 8, 2016 ... of the "Label-Free Detection Market by ... 2020" report to their offering. ... addition of the "Label-Free Detection Market ... to 2020" report to their offering. ...
Breaking Medicine Technology:
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Guruji Mahendra ... 9th, 10th and 11th, 2016 in honor of his birthday on February 10th. ... happiness. Mahendra Trivedi is known by over 250,000 people from over 40 different ...
(Date:2/7/2016)... ... February 07, 2016 , ... Women’s Excellence now ... the most minimally invasive approaches. , Women who have had multiple vaginal births ... factors include surgery to the pelvic floor, connective tissue disorders, and obesity. Women ...
(Date:2/7/2016)... Scottsdale, AZ (PRWEB) , ... February 07, 2016 ... ... & Neck and Facial Plastics, has added Kybella® to his medical and surgical ... is a newly approved FDA injectable medication used as a non-surgical alternative for ...
(Date:2/6/2016)... CA (PRWEB) , ... February 06, 2016 , ... With ... and easily add warm color grades to their footage. A LUT is a Lookup ... pixel's color to the corresponding color indicated by the table. By manipulating each pixel, ...
(Date:2/5/2016)... ... 2016 , ... Steven Tonkinson, 36, of Coconut Grove, Florida, ran the Miami ... in 2003. This year, he ran all 26.2 miles with a green 25-pound ShelterBox ... Miami Heat. , This Sunday, while many are watching the Superbowl, Steven Tonkinson will ...
Breaking Medicine News(10 mins):