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AstraZeneca Submits sNDAs for SEROQUEL XR(TM) for the Treatment of Bipolar Mania and Bipolar Depression
Date:1/3/2008

ts. AstraZeneca is listed in the Dow Jones Sustainability Index (Global) as well as the FTSE4Good Index.

In the United States, AstraZeneca is a $12.44 billion healthcare business with more than 12,000 employees. For nearly three decades, AstraZeneca has offered drug assistance programs side by side with its medicines, and over the past five years, has provided over $3 billion in savings to more than 1 million patients throughout the US and Puerto Rico. AstraZeneca has been named one of the "100 Best Companies for Working Mothers" by Working Mother magazine and is the only large pharmaceutical company named to FORTUNE magazine's 2007 list of "100 Best Companies to Work For." In 2006, for the fifth consecutive year, Science magazine named AstraZeneca a "Top Employer" on its ranking of the world's most respected biopharmaceutical employers.

For more information about AstraZeneca, please visit: http://www.astrazeneca-us.com.

The statements herein include forward-looking statements. By their nature, forward-looking statements and forecasts involve risk and uncertainty. For a discussion of those risks and uncertainties please see the company's Annual Report/Form 20-F for 2006.

References:

1. Data on file, DA-SXR-11.

2. SEROQUEL(R) Prescribing Information

3. Hirschfeld RMA, Calabrese JR, Weissman MM, et al. Screening for Bipolar

in the Community. J Clin Psychiatry. 2003; 64:53-59.

4. US Bureau of the Census. Available at:

http://www.census.gov/popest/national/asrh/NC-EST2005/NC-EST2005-02.xls.

Accessed April 2, 2007.

5. American Psychiatric Association. Diagnostic and Statistical Manual of

Mental Disorders. Fourth Edition Text Revision. Washington DC: 2000.

6. Introduction to Depression and Bipolar Disorder. Available a
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SOURCE AstraZeneca
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