Navigation Links
AstraZeneca Submits sNDAs for SEROQUEL XR(TM) for the Treatment of Bipolar Mania and Bipolar Depression
Date:1/3/2008

d clinical development programs and regulatory filings are planned for a number of other indications.

Important Safety Information for SEROQUEL and SEROQUEL XR

SEROQUEL XR is indicated for the acute and maintenance treatment of schizophrenia. SEROQUEL is indicated for the treatment of depressive episodes in bipolar disorder; acute manic episodes in bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex; and schizophrenia. Patients should be periodically reassessed to determine the need for treatment beyond the acute response.

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk (1.6 to 1.7 times) of death, compared to placebo (4.5% vs 2.6%, respectively). SEROQUEL and SEROQUEL XR are not approved for the treatment of patients with dementia-related psychosis. (See Boxed Warning.)

Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies of major depressive disorder and other psychiatric disorders. Patients of all ages started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. SEROQUEL and SEROQUEL XR are not approved for use in patients under the age of 18 years. SEROQUEL XR is not approved for the treatment of depression; however, SEROQUEL is approved for the treatment of bipolar depression. (See Boxed Warning.)

Hyperglycemia, in some cases extreme and associated with ketoacidosis, hyperosmolar coma, or death, has been reported in patients treated with atypical antipsychotics, including quetiapine. The relationship of atypical use and glucose abnormalities is complicated by the possibility of increased risk of diabetes in the schizophrenic population and the increasing incidence of diabetes in the
'/>"/>

SOURCE AstraZeneca
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Abbott and AstraZeneca Announce Selection of Next-Generation Fenofibrate ABT-335 and CRESTOR(R) Fixed-Dose Combination
2. New Analysis of METEOR Study Demonstrate Effects of AstraZenecas CRESTOR(R) (Rosuvastatin Calcium) on Atherosclerosis in Patients With Two or More Risk Factors for Cardiovascular Disease
3. AstraZeneca Completes Enrollment in First Phase III Study of the Investigational Drug Vandetanib (ZACTIMA)(R) in Non-Small Cell Lung Cancer
4. BioMarin Partner AnGes MG, Inc. Submits BLA to Japanese Ministry of Health
5. Peregrine Pharmaceuticals Submits Clinical Protocol to Initiate Bavituximab Phase II Trial in Patients With Metastatic Breast Cancer
6. Vanda Pharmaceuticals Submits Iloperidone New Drug Application
7. Peregrine Pharmaceuticals Submits Clinical Protocol for New Phase II Trial of Bavituximab in Patients With Metastatic Breast Cancer
8. Roche Submits Application for FDA Approval of ACTEMRA(R) for the Treatment of Rheumatoid Arthritis
9. INVEGA(TM) Significantly Reduced Symptoms of Schizophrenia Compared to SEROQUEL(R) in Acutely Ill, Hospitalized Patients
10. SEROQUEL XR(TM) Receives Approval From FDA for Maintenance Treatment of Schizophrenia
11. UCB Announces Positive Phase III Trial Results for Keppra XR(TM) (levetiracetam) Extended-Release Tablets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... , Sept. 19, 2014 Five MinuteClinic walk-in medical ... Memphis metropolitan area. Three clinics opened in ... month. A fourth clinic will be added in Springfield ... Bartlett is expected to open October 22.  MinuteClinic ... in the United States . The ...
(Date:9/19/2014)... DIEGO , Sept. 19, 2014  Lpath, ... leader in bioactive lipid-targeted therapeutics, announced today that ... 3,605,042 registered shares of common stock and 3,605,042 ... combined purchase price for one registered share of ... one unregistered share of common stock will be ...
(Date:9/19/2014)... VIENNA , Sept. 19, 2014 ... positive interim clinical data for its lead candidate ITCA ... diabetes patients with high baseline HbA1c levels at the ... for the Study of Diabetes (EASD). Data from the ... reduced levels of blood sugar in patients with poorly ...
Breaking Medicine Technology:MinuteClinic Walk-in Medical Clinics Opening in Memphis 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 3Lpath, Inc. Announces $12.5 Million Registered Direct Offering 2Lpath, Inc. Announces $12.5 Million Registered Direct Offering 3Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 2Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 3Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 4
... Approximately ninety-one percent of dentists say patients complaining about dry ... survey conducted by the Academy of General Dentistry (AGD). ... decrease in salivary function. It affects approximately one in ... risk for tooth decay. During the Academy of General Dentistry,s ...
... Pharmaceuticals, Inc. (Nasdaq: RIGL ) today announced that ... July 9, 2009 at 8:00 am EDT (5:00 am PDT). ... investigator of the trial will discuss results of the Company,s ... the Company,s plans for further development and related matters. ...
Cached Medicine Technology:Dry Mouth Linked to Prescription and Over the Counter Drugs 2Dry Mouth Linked to Prescription and Over the Counter Drugs 3Rigel to Host Conference Call to Discuss Results of Its Phase 2b TASKi2 Clinical Trial of R788 in Rheumatoid Arthritis 2
(Date:9/19/2014)... Ariz. (Sept. 19, 2014) - New research published today ... new Ebola cases could reach 6,800 in West Africa ... measures are not enacted. , Arizona State University ... that the rate of rise in cases significantly increased ... that a mass quarantine was put in place, indicating ...
(Date:9/19/2014)... Forest Hills, NY (PRWEB) September 20, 2014 ... Periodontist Prabha Krishnan DMD in Queens, NY now reminds area ... “With more than 80% of our population affected by gum ... problem any longer.” , For over 20 years Dr. Krishnan ... her Forest Hills office location. “Most patients that come in ...
(Date:9/19/2014)... collaborative research team led by Medical College of Wisconsin (MCW) ... and insulin levels in rats, mice and in humans. The ... Genetics . , Leah Solberg Woods, Ph.D., associate ... Children,s Hospital of Wisconsin Research Institute, led the study and ... of the paper identified a gene called Tpcn2 in which ...
(Date:9/19/2014)... Capital Region Periodontics and Dental ... to announce the latest addition to their treatment ... those needing dental implants. Often referred to as ... the fear factor normally associated with traditional gum ... bleeding make, this procedure a very attractive oral ...
(Date:9/19/2014)... York University researchers say a simple test that ... heightened risk for developing Alzheimer,s disease in a ... signs of dementia., Faculty of Health Professor Lauren ... the study asked the participants to complete four ... screen laptop computers. The test aimed at detecting ...
Breaking Medicine News(10 mins):Health News:Research predicts possible 6,800 new Ebola cases this month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 3Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 2Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 3Health News:Simple test can help detect Alzheimer's before dementia signs show: York U study 2
... The British Association for Psychopharmacology (BAP) has released fresh ... and addiction in the Journal of Psychopharmacology , ... researched the new, comprehensive guidelines, offering practitioners a detailed ... clinical decisions. The new BAP guidelines target treatment ...
... with intact proteins of the same kind, thereby triggering ... discovered by researchers from the RUB Heart and Diabetes ... Hendrik Milting in an interdisciplinary research project with colleagues ... report in the Journal of Biological Chemistry . ...
... , WEDNESDAY, May 23 (HealthDay News) -- The ... reduced through a multi-pronged approach that includes more training ... to a new German study. Despite legal regulations ... as bed rails and belts still are frequently used ...
... resilient metal wire designed to gather and compress diseased lung ... a subtype of the disease that involves specific, usually isolated ... multicenter international trial conducted in the Netherlands, Germany and France. ... be easily implanted and is designed to take the place ...
... imaging (MRI) provides an indication of a breast tumor,s ... clinical examination, according to a new study published online ... with breast cancer often undergo chemotherapy prior to surgery. ... known as neoadjuvant chemotherapy, are more likely to achieve ...
... Ill. -- Children born with cleft lip, cleft palate ... appearance. Patients can face serious airway, feeding, speech ... challenges, Laura Swibel Rosenthal, MD, of Loyola University Medical ... of Otolaryngologic Clinics of North America . ...
Cached Medicine News:Health News:British experts update addiction treatment guidelines 2Health News:Aggregating instead of stabilizing: New insights into the mechanisms of heart disease 2Health News:Study Offers Ways to Decrease Use of Restraints at Nursing Homes 2Health News:Tiny implanted coil improves lung function in patients with severe emphysema 2Health News:Tiny implanted coil improves lung function in patients with severe emphysema 3Health News:Breast MRI helps predict chemotherapy's effectiveness 2Health News:Cleft lip/palate cause much more than cosmetic problems 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: