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AstraZeneca Completes Enrollment in First Phase III Study of the Investigational Drug Vandetanib (ZACTIMA)(R) in Non-Small Cell Lung Cancer
Date:11/30/2007

f the world's leading pharmaceutical companies with health care sales of $26.47 billion and leading positions in sales of gastrointestinal, cardiovascular, neuroscience, respiratory, oncology and infection products. AstraZeneca is listed in the Dow Jones Sustainability Index (Global) as well as the FTSE4Good Index.

In the United States, AstraZeneca is a $12.44 billion health care business with more than 12,000 employees. For nearly three decades, AstraZeneca has offered drug assistance programs side by side with its medicines, and over the past five years, has provided over three billion in savings to more than one million patients throughout the U.S. and Puerto Rico. AstraZeneca has been named one of the "100 Best Companies for Working Mothers" by Working Mother magazine and is the only large pharmaceutical company named to FORTUNE magazine's 2007 list of "100 Best Companies to Work For." In 2006, for the fifth consecutive year, Science magazine named AstraZeneca a "Top Employer" on its ranking of the world's most respected biopharmaceutical employers.

For more information about AstraZeneca, please visit: http://www.astrazeneca-us.com

ZACTIMA is a registered trademark of the AstraZeneca group of companies.

(1) Natale RB et al. ZD6474 versus gefitinib in patients with advanced

NSCLC: Final results from two-part, double-blind randomized phase II

trial. Journal of Clinical Oncology, Vol 24, No 18S, 2006: 7000.

(2) Heymach JV et al. Randomized, Placebo-Controlled Phase II Study of

Vandetanib Plus Docetaxel in Previously Treated Non-Small-Cell Lung

Cancer Journal of Clinical Oncology, Vol 25, No 27, 2007: 4270-4277.


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