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AssureRx Expands GeneSightRx® Pharmacogenetic Profile with Sixth Gene to Enhance Guidance of Psychiatric Drug Prescribing
Date:2/14/2011

CINCINNATI, Feb. 14, 2011 /PRNewswire/ -- AssureRx Health, Inc. today announced that it has expanded its laboratory-developed GeneSightRx® pharmacogenetic test with a sixth gene, CYP2C9, to further support clinicians in prescribing medications for behavioral health patients.

The addition of the CYP2C9 gene, variations of which can cause loss of function involved in the metabolism of certain psychotropic medications, provides physicians with further information on gene polymorphisms responsible for variations in the metabolism of antidepressant and antipsychotic medications. GeneSightRx will now measure and analyze fifty clinically important genetic variants of six genes that affect patients' response to medications prescribed in psychiatric medicine.

The enhanced six-gene Web-based therapeutic decision support product analyzes genetic variants which may affect a patient's ability to tolerate or respond to psychotropic medications. GeneSightRx integrates the analysis of genes and their variations to obtain an evidence-based pharmacogenetic profile. These gene variations are then analyzed against 26 FDA-approved drugs to help physicians select the appropriate psychotropic medications for each patient. In addition to the CYP2C9 gene, GeneSightRx analyzes genetic variations in the CYP2D6, CYP2C19, and CYP1A2 genes, as well as the serotonin transporter gene SLC6A4 and the serotonin 2A receptor gene 5HTR2A.  

"GeneSightRx provides objective measures to help physicians avoid prescribing drugs that may cause adverse drug reactions or poor response in certain patients. Improving drug safety is a key company objective," said James S. Burns, president & CEO of AssureRx. "Our goal is to build the leading medical informatics company providing pharmacogenetic and other treatment decision support products to help physicians individualize the t
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SOURCE AssureRx Health, Inc.
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