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Artikel im American Journal of Cardiology zeigt gute Gefäßheilung nach MiStent-SES-Implantation
Date:11/21/2013

sgabe des American Journal of Cardiology vom 15. November 2013 erschien der Artikel „Serial Assessment of Early and Late Vascular Responses After Implantation of an Absorbable-Coating Sirolimus-Eluting Stent: An Optical Coherence Tomography Sub-Study From The First-in-Human DESSOLVE I Trial." Hauptautor dieses Artikels ist Guilherme Attizzani, M.D., wissenschaftlicher Mitarbeiter am Harrington Heart and Vascular Institute des University Hospitals Case Medical Center.

Informationen zum MiStent SES

Das MiStent Sirolimus-eluierende Koronarstentsystem aus resorbierbarem Polymer (MiStent SES®) wurde speziell für die optimierte Heilung in Patienten mit koronarer Herzerkrankung entwickelt. Die schnell resorbierbare Beschichtung des MiStent SES soll die Arzneimittelfreisetzung genauestens und konsistent steuern und die Polymer-Expositionsdauer begrenzen. Dies wirkt sich vorteilhaft auf die Sicherheitsrisiken bei derzeit am Markt erhältlichen Arzneimittel-eluierenden Stent-Technologien aus.

Das innovative MiStent-SES-System besitzt eine neuartige Stentbeschichtung mit einem kristallinen Wirkstoff (Sirolimus) und einem resorbierbarem Polymer. Die Beschichtung sorgt für eine kontrollierte und anhaltende Freisetzung therapeutischer Arzneimitteldosen, während das Polymer weich wird und sich vom Stent in das benachbarte Gewebe ablöst. Diese Eigenschaften sollen sich gegenüber herkömmlichen Dauer-Polymer-DES vorteilhaft auf die Sicherheit auswirken.

Durch den Einsatz eines zugelassenen Wirkstoffs (Sirolimus) und die Verwendung von Polymer (PLGA) ermöglicht die von Micell patentierte überkritische Fluidtechnologie das Auftragen einer streng kontrollierten Wirkstoff-Polymer-Beschichtung auf einen blanken Metallstent. Das MiStent SES nutzt die Vorteile des (CE-zertifizierten) Eurocor Genius® MAGIC Cobaltchrom-Koronars
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SOURCE Micell Technologies, Inc.
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