Navigation Links
Arrien Pharmaceuticals Founder's closes $2.0 Million Series A Financing
Date:9/12/2011

ANSONIA, Conn., Sept. 12, 2011 /PRNewswire/ -- Arrien Pharmaceuticals LLC (Arrien) is a new start-up Company located in the Connecticut & Salt Lake City area announces today of its successful completion of Series A financing from contributions by the founders of the company and currently engaged in the discovery and development of breakthrough novel small molecules targeting cell signalling pathways. Arrien developed a proprietary platform - Fragment-Field Drug Design (FFDD™) Technology with the efforts of experienced Medicinal Chemists and initiated to discover small molecule targeted therapeutics for addressing unmet need in treating Parkinson's, Alzheimer's, Down's syndrome, Huntington's, Multiple Cancer Indications, Rheumatoid Arthritis (RA), Type 2 Diabetes and Obesity diseases.

ORS-1006 is the Company's lead small molecule First-in-Class candidate inhibitor of Protein Kinase for Parkinson Disease (PD). ORS-1006 shows neuroptotective effect in cell culture models of PD, potent activity in Parkinsonian mouse models, kinase selective and has demonstrated an excellent PK profile. Arrien completed early pre-clinical PK/PD studies, IND-enabling toxicology studies for ORS-1006, which included Maximum Tolerated Dose (MTD) studies and repeat-dose toxicity studies in rodents and non-rodents is expected to start by Q4 2011.

In addition, Arrien has identified an active First-in-Class ARN-1032 and ARN-3016 which are potent inhibitors of protein kinases and demonstrated potent anticancer activities in a variety of cancer cell lines. Currently Arrien is conducting lead optimization process and early PK studies.

Mr. Rajendra P. Appalaneni Chairman/CEO, an experienced Chemist/Pharmacist/Pharmacologist, Successful Serial Entrepreneur and The Founder/Chief Executive Officer (CEO) of Arrien Pharmaceuticals commented at the Arrien board meeting on completion of this financing to advance Arrien promising pre-clinical Parki
'/>"/>

SOURCE Arrien Pharmaceuticals LLC
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Savient Pharmaceuticals Names Kenneth J. Zuerblis Chief Financial Officer
2. HemaQuest Pharmaceuticals Completes Patient Enrollment in Phase 2 Clinical Study of HQK-1001 in Patients With Sickle Cell Disease
3. Optimer Pharmaceuticals DIFICID Featured in 11 Presentations at 51st ICAAC
4. AcelRx Pharmaceuticals to Present at the Rodman & Renshaw Global Investment Conference
5. Valeant Pharmaceuticals Announces Mailing of Offer and Take-Over Bid Circular to Shareholders of Afexa
6. Rescheduled Webcast: Isis Pharmaceuticals Hosts Dr. John Kastelein to Review Mipomersen Long-term Data Recently Presented at ESC Congress 2011
7. Anthera Pharmaceuticals Announces Notice of Allowance of U.S. Patent Application Covering A-002 Plus Statin Compositions
8. Panmira and FLAP LLCs Spun Out of Amira Pharmaceuticals
9. Oramed Pharmaceuticals to Present at Rodman & Renshaw 13th Annual Global Investment Conference
10. Ampio Pharmaceuticals Executes License and Development Agreement with Daewoong Co. Ltd. to Commercialize Zertane™ in South Korea
11. Auxilium Pharmaceuticals Announces Additional Data from Three-Year XIAFLEX® Recurrence Study in Dupuytrens Contracture in E-poster at ASSH Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... 28, 2015  Delays in the launch and ... down the decision-making process, resulting in missed opportunities ... for biopharmaceutical companies to develop a tactical approach ... quicker and more meaningful insights. ... nearly three-quarters of benchmarked study participants use review ...
(Date:8/28/2015)... Aug. 28, 2015 ... the addition of the "12th Annual Report ... report to their offering. The ... Manufacturing Capacity and Production is the most recent ... current and projected future capacity and production. The ...
(Date:8/28/2015)... Research and Markets ( ... "Investigation Report on China,s Insulin Aspart Market, ... Developed by Novo Nordisk, insulin aspart (under the ... for the treatment of diabetes. Compared with human ... analog, starts working fast and reports higher peak ...
Breaking Medicine Technology:Expediting the Pharmaceutical Market Research Process for Faster Insights 212th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2
... 21, 2011 In recognition of Red Ribbon Week, ... fastest growing form of substance abuse in the U.S., ... drug and alcohol treatment in Illinois , Gateway Foundation ... efforts taking place in schools by reaching out to ...
... CHARLESTON, S.C., Oct. 21, 2011 Federal, state and ... Carolina,s growing biomedical research effort with the dedication of ... treatments for major diseases. The complex, housing ... the traditional research approach by combining scientists from different ...
Cached Medicine Technology:Gateway Foundation Alcohol & Drug Treatment Honors Red Ribbon Week in October 2Gateway Foundation Alcohol & Drug Treatment Honors Red Ribbon Week in October 3MUSC Dedicates New Bioengineering and Drug Discovery Hubs 2
(Date:8/29/2015)... ... August 29, 2015 , ... On Saturday, September 19, 2015, Diane ... Foundation (Meso Foundation) will present an educational program titled “Asbestos and Your Health.” ... through 9:30 PM (doors open at 6:45pm) at Calvary United Methodist Church, 16 E ...
(Date:8/29/2015)... ... ... Brands like Toppik , Eau Thermale Avene and Bliss are now available ... $49.00 was required to qualify for free standard shipping,” said Jennifer Ramirez, the public ... regardless of the item’s selling price.” , With competitive pricing in the e-commerce market ...
(Date:8/29/2015)... ... , ... The popular television program VOICES IN AMERICA, hosted by legendary star ... devoting an entire short segment to the subject of diabetes. Diabetes is a debilitating ... daily basis, but recent advancements in medical science may prove to be a significant ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... Day at the Zoo to celebrate children helping children, a thank you to ... throughout West Ohio have contributed to the United Methodist initiative to end malaria ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... Medical Devices:, Understanding the FDA’s Position and Best Practices for Compliance, **Presented ... , This workshop, chaired by internationally renowned expert Fubin Wu, has ...
Breaking Medicine News(10 mins):Health News:Mesothelioma Applied Research Foundation to Hold Educational Class About Asbestos and Mesothelioma Prevention 2Health News:TheBeautyPlace.com Discounts Shipping on Select Brands 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 2Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 4Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 5
... with an eye-alignment disorder called infantile esotropia have ... up after corrective surgery, reports a study in ... Pediatric Ophthalmology and Strabismus). , Led by James ... Southwest Texas, Dallas, the researchers assessed developmental milestones ...
... highest-risk professions for ergonomic injury, according to a new ... indicates that interpreting causes more physical stress to the ... assembly line work. It also found a direct link ... of the interpreter and an increase in the risk ...
... reliability, improves information flow, facilitates documentation and, compliance, and ... ... outcomes., ... release of an enhanced NaviCare(R) WatchChild(R),solution, following receipt of marketing ...
... to Focus on Healthcare, Trade and the Economy, ... and think tanks can take part in National Small,Business ... the,agency,s premier annual event., These public policy forums ... business and the economy:, WHO:, Secretary Michael ...
... no cost to Twin Cities, consumers, the bi-monthly magazine,published in partnership ... content written and edited by the most experienced health ... journalists in ... Twin Cities,residents will soon have a unique health and wellness resource ...
... A new hybrid hearing aid/cochlear implant device designed for ... UT Southwestern Medical Center otolaryngologists, as part of a multisite, ... System, or EAS, is already used in Europe, but not ... a population currently falling through the cracks borderline cases ...
Cached Medicine News:Health News:Infantile esotropia linked to developmental delays 2Health News:RIT study: Sign language interpreters at high ergonomic risk 2Health News:Hill-Rom's NaviCare(R) WatchChild(R) Solution Provides Enhanced Information Technology Solutions for Obstetrical Care 2Health News:Live Webcast of SBA's National Small Business Week Policy Forums Scheduled 2Health News:The Best Things in Life Are ... In Better Health & Living(R), A Free, Premium Magazine Launching April 26 in the Twin Cities 2Health News:The Best Things in Life Are ... In Better Health & Living(R), A Free, Premium Magazine Launching April 26 in the Twin Cities 3Health News:UT Southwestern testing new hybrid hearing device combining advantages of hearing aids, implants 2
... is precision, ergonomics, and value!, ... with soft non-slip, contoured handle , ... light plunger spring action , Completely ... without the need for recalibration , ...
Inquire...
... pipette is ideal for repeated ... Fixed volume FInnpipettes offer the ... other Finnpipette Digital pipettes: ... (1-40ul), Soft-touch tip ejection, Safety ...
100L...
Medicine Products: