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Arpida Comments on FDA's Anti-infective Drugs Advisory Committee Outcome
Date:11/20/2008

red pneumonia, ventilator-associated pneumonia and healthcare-associated pneumonia.

Committed to the future development and commercialization of iclaprim, Arpida has anticipated potential scenarios and instituted judicious business plans that allow for continued development of its portfolio of products. Arpida continues to work in close collaboration with regulatory authorities to obtain intravenous iclaprim market authorization in the United States and Europe.

About MRSA

Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacteria that is resistant to most commonly available antibiotics.(i) MRSA infections occur most frequently among persons who have weakened immune systems in hospitals and healthcare facilities; however community-associated MRSA infections, such as abscesses, boils, and other pus-filled lesions, are increasingly being diagnosed in healthy people who have not been recently hospitalized or have undergone medical procedure.(iii), (ii)The most common antibiotic used to treat MRSA infections is vancomycin, but recent evidence suggests resistance to vancomycin is on the rise.(iii), (iv)

Approximately 2.3 million people in the United States acquire MRSA and 89.4 million people are colonized with S. aureus annually, according to the Centers for Disease Control and Prevention (CDC).(i), (v) An estimated 292,000 hospitalizations with a diagnosis of S. aureus infection occur annually in U.S. hospitals and, of these, approximately 126,000 hospitalizations are related to MRSA.(vi) MRSA is responsible for an average of 94,000 life-threatening infections and 18,650 deaths each year in the United States.(vii)

About Iclaprim

Iclaprim is an antibiotic currently in development for the treatment of serious infections requiring hospitalization caused by Gram-positive bacteria, including those caused by MRSA. Iclaprim was designed to meet a growing me
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SOURCE Arpida Ltd.
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