Navigation Links
Arno Therapeutics to Present Positive, New Data Supporting the Potential of Onapristone in Endometrial and Breast Cancers at ASCO 2013 Annual Meeting
Date:5/15/2013

FLEMINGTON, N.J., May 15, 2013 /PRNewswire/ -- Arno Therapeutics, Inc. (OTCQB: ARNI), a clinical stage biopharmaceutical company focused on the development of oncology therapeutics, today announced new, positive data from three studies supporting its investigational compound onapristone to be presented at the American Society of Clinical Oncology (ASCO) 2013 Annual Meeting, which is being held May 31-June 4, 2013 in Chicago, Illinois.

Three separate preclinical studies support further investigation of onapristone - an orally-administered, investigational type 1 progestin receptor antagonist - and the development of a diagnostic test for the compound to identify patients with activated progesterone receptor (APR) as a potential biomarker of anti-progestin activity in endometrial and breast cancers.  Recently, Arno Therapeutics announced its collaboration with Clarient Diagnostic Services Inc., a GE healthcare company, and leading provider of cancer diagnostic testing, to develop a diagnostic test to identify cancerous tumors with APR.

Onapristone is believed to work by binding to a protein called the progesterone receptor, thereby inhibiting dimerization, phosphorylation and DNA transcription activity. Progesterone receptors (PRs) are found in particular cells including those of the female reproductive tissue and some cancers.[i] The hormone progesterone binds to the receptors and may cause the cells to grow.i  Preclinical studies have shown that PRs can play a role as drivers of malignant cell growth in certain cancers."We are pleased with the findings as they support the development of a diagnostic test for onapristone to help identify patients with activated progesterone receptors in endometrial and breast cancers who are most likely to benefit from treatment in these difficult-to-treat diseases," said Glenn Mattes , chief executive officer
'/>"/>

SOURCE Arno Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
3. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
4. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
5. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
6. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
7. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
8. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
9. Frost & Sullivan: High Uptake of New Drug Therapies and Aging Population Expansion Keep the U.S. Retinal Therapeutics Market Buoyant
10. Zenobia Therapeutics, Inc. And BioBlocks, Inc. Announce Sale Of A Joint Fragment Library Ideal For Screening By All Popular Methods
11. New Forecast Shows Global Protein Therapeutics Market to Reach $143.4 Billion by 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... 30, 2014 Boston Scientific Corporation (NYSE: ... 2014 Credit Suisse Annual Healthcare Conference on Tuesday, November ... Dan Brennan , executive vice president and chief ... beginning at approximately 8:00 a.m. PT followed by a ... of the presentation and question and answer session will ...
(Date:10/30/2014)... NEW YORK , Oct. 30, 2014  The ... United States is growing steadily, thanks to ... years, as a result of the economic downturn, retail ... was a year of opportunities, as the number of ... market researcher,s report, Retail Clinics Market Overview and ...
(Date:10/30/2014)... NOTTINGHAM, United Kingdom , Oct. 30, 2014 /PRNewswire/ ... Inc., (Nasdaq: CBRX ) and ... assist drug developers with improved efficiency during clinical development ... San Diego next week. This ... enabling technologies platform, which it launched earlier this month. ...
Breaking Medicine Technology:Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2Report: Drugstore Chains Drive Retail Clinic Growth 2Report: Drugstore Chains Drive Retail Clinic Growth 3Molecular Profiles To Launch US Strategic Alliance At AAPS 2Molecular Profiles To Launch US Strategic Alliance At AAPS 3
... Findings Reinforce March of Dimes Message: Start Taking a ... 11 Women who take folic acid supplements for ... cut their risk of having a premature baby by ... online journal, PLOS Medicine.The study links pre-conceptional folate supplementation ...
... Announces Positive Top Line Results of its Clinical Study ... Mass., May 11 Logical Therapeutics, Inc (Logical), a ... treat diseases associated with inflammation, today announced that Peter ... has been elected to the Company,s Board of Directors. ...
Cached Medicine Technology:Taking Folic Acid for a Year Before Pregnancy May Reduce Risk of Preterm Birth 2Logical Therapeutics Appoints Peter A. Lankau as CEO and Director 2Logical Therapeutics Appoints Peter A. Lankau as CEO and Director 3Logical Therapeutics Appoints Peter A. Lankau as CEO and Director 4
(Date:10/31/2014)... October 31, 2014 At the start ... families narrowly escaping carbon monoxide poisoning in their homes. ... weeks away, one family-owned, Missouri-based heating and cooling company ... making sure families start the home heating season with ... secure. , Beginning Nov. 1, 2014, E and ...
(Date:10/31/2014)... 2014 (HealthDay News) -- Surgery for low back pain ... the United States you live, a new report says. ... back pain at some point in their lives, and ... care for a spine problem," co-author Brook Martin, of ... said in a college news release. In spinal ...
(Date:10/31/2014)... research suggests that insomnia is a major contributor to ... fatal injuries. The results underscore the importance of the ... Sleep Awareness Project. , Results show that the risk ... with the number of insomnia symptoms present. People with ... likely to die from a fatal injury than those ...
(Date:10/31/2014)... Colorado (PRWEB) October 31, 2014 The ... that this workout program was developed by Dan Long, ... become well-known as a fitness professional and life coach. ... fat and having toned muscles is not impossible , ... based on suspension training. Suspension training promises efficiency when ...
(Date:10/31/2014)... Fl. (PRWEB) October 31, 2014 ... for boys and girls in grades 6-12, is ... potential for sports injuries and concussions, becoming the ... administer the ImPACT (Immediate Post-Concussion Assessment and Cognitive ... a 'Former NFL Player' lawsuit grabs the headlines, ...
Breaking Medicine News(10 mins):Health News:Many Homeowners Missing Key Safety Risks with Home Heating;Missouri-based Company E and Q Announces New Safety Check 2Health News:Many Homeowners Missing Key Safety Risks with Home Heating;Missouri-based Company E and Q Announces New Safety Check 3Health News:Spinal Surgery Varies by Region in U.S.: Study 2Health News:Insomnia increases risk of motor vehicle deaths, other fatal injuries 2Health News:Suspension Revolution Review Reveals Dan Long's New Suspension Workout Plan 2Health News:Florida Air Academy Tackling Concussions Head-On 2Health News:Florida Air Academy Tackling Concussions Head-On 3
... UCLA team develops device giving patients freedom of movement, better ... An automated artificial kidney that can be worn on ... the insulin pump is to diabetes patients. , The automated, ... to a paper in the current issue of Clinical ...
... SUCCESS, N.Y., July 25 Anthony Shih,M.D., ... Officer and Vice President,of Strategic Planning, after ... a,national foundation committed to improving U.S. health ... on Health Care Quality,Improvement and Efficiency., ...
... therapy may be due to genetic factors , , FRIDAY, ... the long-held belief that the hepatitis C virus (HCV) ... HIV patients are treated with highly active antiretroviral therapy ... HIV-infected drug users are also infected with HCV. Intravenous ...
... Authority offers patients consumers tips and encourages them ... HARRISBURG, Pa., July 25 The Pennsylvania,Patient ... which,is a national effort to encourage patients and ... asking questions and learning,everything they can about their ...
... of Defense and Federal Agencies in, the execution ... four-day, multi-agency collaborative training event designed to ... complex incident response scenarios. Dataline is ... infrastructure for medical use during the exercise., NORFOLK, ...
... Ill., July 25 Sagent Pharmaceuticals, Inc.,a ... it,has launched amiodarone HCl injection, USP, a ... prophylaxis of frequently recurring,ventricular fibrillation and hemodynamically ... heart beat.,Sagent,s amiodarone HCl injection will be ...
Cached Medicine News:Health News:IPRO Welcomes Back Anthony Shih as Chief Quality Officer, Strategic Planning Lead 2Health News:Study Disproves Belief That Hepatitis C Blunts HIV Drugs 2Health News:Patient Safety Authority Supports 'National Patient Safety Day' 2Health News:Patient Safety Authority Supports 'National Patient Safety Day' 3Health News:Dataline Announces Participation in Operation Golden Phoenix 2Health News:Dataline Announces Participation in Operation Golden Phoenix 3Health News:Sagent Pharmaceuticals Launches Amiodarone HCl Injection, USP 2Health News:Sagent Pharmaceuticals Launches Amiodarone HCl Injection, USP 3
Cordis DUCOR Catheters are available in a broad variety of French sizes and configurations. These catheters combine an atraumatic tip with either a braided or non-braided body....
The advanced center-of-the-arc system allows an infinite choice of trajectories. The system's lightweight durable frame provides accuracy, simplicity, patient mobility and accessibility....
The CRW system epitomizes simplicity, quality assurance, and versatility....
Used for complex diagnostic and interventional procedures....
Medicine Products: