Navigation Links
Arno Therapeutics to Present Positive, New Data Supporting the Potential of Onapristone in Endometrial and Breast Cancers at ASCO 2013 Annual Meeting
Date:5/15/2013

FLEMINGTON, N.J., May 15, 2013 /PRNewswire/ -- Arno Therapeutics, Inc. (OTCQB: ARNI), a clinical stage biopharmaceutical company focused on the development of oncology therapeutics, today announced new, positive data from three studies supporting its investigational compound onapristone to be presented at the American Society of Clinical Oncology (ASCO) 2013 Annual Meeting, which is being held May 31-June 4, 2013 in Chicago, Illinois.

Three separate preclinical studies support further investigation of onapristone - an orally-administered, investigational type 1 progestin receptor antagonist - and the development of a diagnostic test for the compound to identify patients with activated progesterone receptor (APR) as a potential biomarker of anti-progestin activity in endometrial and breast cancers.  Recently, Arno Therapeutics announced its collaboration with Clarient Diagnostic Services Inc., a GE healthcare company, and leading provider of cancer diagnostic testing, to develop a diagnostic test to identify cancerous tumors with APR.

Onapristone is believed to work by binding to a protein called the progesterone receptor, thereby inhibiting dimerization, phosphorylation and DNA transcription activity. Progesterone receptors (PRs) are found in particular cells including those of the female reproductive tissue and some cancers.[i] The hormone progesterone binds to the receptors and may cause the cells to grow.i  Preclinical studies have shown that PRs can play a role as drivers of malignant cell growth in certain cancers."We are pleased with the findings as they support the development of a diagnostic test for onapristone to help identify patients with activated progesterone receptors in endometrial and breast cancers who are most likely to benefit from treatment in these difficult-to-treat diseases," said Glenn Mattes , chief executive officer
'/>"/>

SOURCE Arno Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
3. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
4. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
5. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
6. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
7. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
8. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
9. Frost & Sullivan: High Uptake of New Drug Therapies and Aging Population Expansion Keep the U.S. Retinal Therapeutics Market Buoyant
10. Zenobia Therapeutics, Inc. And BioBlocks, Inc. Announce Sale Of A Joint Fragment Library Ideal For Screening By All Popular Methods
11. New Forecast Shows Global Protein Therapeutics Market to Reach $143.4 Billion by 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... MISSION, Kan. , May 5, 2015 ... priorities for you? If you,re like most adults, monitoring ... of your health care routine. But what about vision ... When adults reach their 40s, they ... which can impact their daily lives and job performance. ...
(Date:5/5/2015)... Research and Markets ( http://www.researchandmarkets.com/research/74vlb2/electro_surgical ... "Electro Surgical Market" report to their offering. ... to achieve a CAGR of 7% for the ... for patients as well as surgeons such as ... marks, bleeding control and improved accuracy are some ...
(Date:5/5/2015)... Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) ... for the three months ended March 31, 2015 compared ... million for the same period in 2014.  Isis, significantly ... milestone payments earned from its partners compared to the ... reported a loss from operations of $9.3 million for ...
Breaking Medicine Technology:Eye Care as You Age 2Eye Care as You Age 3Eye Care as You Age 4Global Electro Surgical Market 2015 2Isis Reports Financial Results and Highlights for First Quarter 2015 2Isis Reports Financial Results and Highlights for First Quarter 2015 3Isis Reports Financial Results and Highlights for First Quarter 2015 4Isis Reports Financial Results and Highlights for First Quarter 2015 5Isis Reports Financial Results and Highlights for First Quarter 2015 6Isis Reports Financial Results and Highlights for First Quarter 2015 7Isis Reports Financial Results and Highlights for First Quarter 2015 8Isis Reports Financial Results and Highlights for First Quarter 2015 9Isis Reports Financial Results and Highlights for First Quarter 2015 10Isis Reports Financial Results and Highlights for First Quarter 2015 11Isis Reports Financial Results and Highlights for First Quarter 2015 12Isis Reports Financial Results and Highlights for First Quarter 2015 13
(Date:5/5/2015)... NY (PRWEB) May 05, 2015 The newly minted ... the experiences of Dr. Brad Reedy from his 20 ... Regan was asked why she chose to publish a parenting book ... a parent (and publisher) is the idea that it is a ... and our children are on the trek sometimes together and sometimes ...
(Date:5/5/2015)... CA (PRWEB) May 05, 2015 Nutritional ... and actually prevent a variety of health conditions and ... this modern research to adopt clean eating methods to ... artificial dyes associated with over-consumption of fast and processed ... plans easy to follow and report feeling better ...
(Date:5/5/2015)... This year, PolyU researchers garnered two Grand ... three Gold Medals and four Silver Medals at the ... , (1) Grand Prize and Gold Medal with the ... and Fitting, Principal Investigator: Dr Allan Chee-kooi CHAN, Institute ... very much on the “mannequin” for many tasks involved ...
(Date:5/5/2015)... Pa (PRWEB) May 05, 2015 The ... of accelerated aging that correlate with slower information processing, ... Pittsburgh Graduate School of Public Health . , ... patients with type 1 diabetes for cognitive difficulties. If ... their diabetes. The study, funded by the National ...
(Date:5/5/2015)... May 05, 2015 Barnabas Health, the ... launch of a new healthy cooking video series starring ... semi-finalist on Bravo’s Top Chef, teamed up with Barnabas ... and healthy living. In support of the series, ... and the videos will be showcased on social media. ...
Breaking Medicine News(10 mins):Health News:The Last Parenting Book You Will Ever Need: Veteran Publisher Judith Regan Releases A Provocative New Book By Dr. Brad Reedy, "The Journey Of The Heroic Parent" 2Health News:The Last Parenting Book You Will Ever Need: Veteran Publisher Judith Regan Releases A Provocative New Book By Dr. Brad Reedy, "The Journey Of The Heroic Parent" 3Health News:Diet Doc Introduces Diet Plans that Teach Patients how to Eat Clean by Getting Back to Basics and Exchanging Processed Foods for Clean, Nutritious Foods 2Health News:Diet Doc Introduces Diet Plans that Teach Patients how to Eat Clean by Getting Back to Basics and Exchanging Processed Foods for Clean, Nutritious Foods 3Health News:PolyU wins top prizes in Geneva’s Invention Expo 2Health News:PolyU wins top prizes in Geneva’s Invention Expo 3Health News:PolyU wins top prizes in Geneva’s Invention Expo 4Health News:PolyU wins top prizes in Geneva’s Invention Expo 5Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 2Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 3Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 4Health News:Barnabas Health Teams Up With Celebrity Chef Sam Talbot To Launch "Life Is Better Healthy" Cooking Video Series 2Health News:Barnabas Health Teams Up With Celebrity Chef Sam Talbot To Launch "Life Is Better Healthy" Cooking Video Series 3
... 28 (HealthDay News) -- Adolescents with large social networks of ... than teens who play a less central role in their ... findings from the study of 2,610 U.S. students in grades ... teen,s social network may help delay the start of drinking. ...
... HealthDay Reporter , WEDNESDAY, Sept. 28 (HealthDay News) -- ... in children with attention-deficit/hyperactivity disorder (ADHD) is continuing to climb, ... a new study finds. The study,s authors tracked U.S. ... use of ADHD drugs was the highest among kids aged ...
... of the American Physical Society,s (APS) Division of Fluid ... from across the physical sciences, engineering, and medicine. Topics ... the quirks of flying; why coffee spills; and how ... The meeting will take place November 20-22, ...
... Health indicates 31 percent of Missouri children are overweight ... for students and nutritional standards for school meals beyond ... the University of Missouri shows Jump Into Action (JIA), ... unhealthy youth behaviors. JIA aims to help fifth-graders ...
... the Oct. 2-6 microTAS 2011 conference, the premier ... and detection technologies for life science and chemistry, ... low-cost, method for separating and safely collecting concentrated ... research results resolve the critical technical challenge of ...
... drug that,s made enormous headway in recent years against ... be permanent and worsens even months after treatment ends. ... in the September issue of Neurology , was ... effort to track oxaliplatin-based nerve damage through relatively cheap ...
Cached Medicine News:Health News:Number of U.S. Kids on ADHD Meds Keeps Rising 2Health News:Number of U.S. Kids on ADHD Meds Keeps Rising 3Health News:Number of U.S. Kids on ADHD Meds Keeps Rising 4Health News:APS Division of Fluid Dynamics meeting: Highlights and media registration 2Health News:APS Division of Fluid Dynamics meeting: Highlights and media registration 3Health News:APS Division of Fluid Dynamics meeting: Highlights and media registration 4Health News:APS Division of Fluid Dynamics meeting: Highlights and media registration 5Health News:Students 'jump into action' for better health 2Health News:New UC research promises better collection of prostate cancer cells 2Health News:New UC research promises better collection of prostate cancer cells 3Health News:Popular colorectal cancer drug may cause permanent nerve damage 2
Long handle occluder - Black...
6 inch hand held occlcuder with 49 holes...
Designed to provide occlusion while permitting observation of the eye. Helpful to determine if only one eye is deviating. Approximately 9 inches long....
Short handle occluders are about 6 inches long....
Medicine Products: