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Arena Pharmaceuticals Expands GPR119 Patent Portfolio for Type 2 Diabetes
Date:3/10/2011

SAN DIEGO, March 10, 2011 /PRNewswire/ -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA) announced today that it was issued United States Reissue Patent No. RE42,190 with claims to methods of identifying compounds that modulate the activity of the GPR119 receptor. This invention stems from the discovery by Arena's scientists of the GPR119 receptor, a target for identifying small molecules for the treatment of diabetes.

"Targeting GPR119 with small molecules represents a promising new approach for the treatment of type 2 diabetes," stated Dominic P. Behan, Ph.D., Arena's Senior Vice President and Chief Scientific Officer. "Our growing GPR119 patent portfolio covers technologies and tools that are useful in identifying orally active drug candidates. We are pursuing exclusive partnering opportunities for our internally discovered GPR119 agonists, including APD597 and next-generation compounds, and non-exclusive licensing opportunities for our portfolio of patents and patent applications related to the discovery and development of GPR119 receptor agonists."

Arena recently had additional GPR119 patent successes: United States Patent No. 7,893,235 issued with claims to isolated GPR119 nucleic acid sequences as well as vectors, plasmids and host cells containing those sequences; and United States Patent No. 7,816,492 issued with claims to isolated and recombinant GPR119 amino acid sequences. In addition, Arena holds patents on related GPR119 subject matter issued by patent offices of foreign jurisdictions, including the European Patent Office (EP 1133559, EP 1584683 and EP 1849866) as well as the patent offices of Canada, Australia, South Korea, Mexico, Hong Kong and New Zealand.

The technologies covered by Arena's patents and patent applications are related to the discovery and development of GPR119 receptor agonists, including materials and methods that may be used to id
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SOURCE Arena Pharmaceuticals, Inc.
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