Navigation Links
Arena Pharmaceuticals Announces Positive Phase 2 Clinical Trial Results of APD125 for the Treatment of Insomnia
Date:9/25/2007

SAN DIEGO, Sept. 25 /PRNewswire-FirstCall/ -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA) today announced positive preliminary results from its Phase 2 clinical trial of APD125 in patients with chronic insomnia. APD125 is an orally available drug candidate discovered by Arena that is being evaluated in insomnia patients who have difficulty maintaining sleep after initial sleep onset. When compared to placebo, patients treated with APD125 experienced statistically significant improvements in measurements of sleep maintenance, or the ability to maintain sleep during the night after falling asleep. The improvements in measurements of sleep maintenance were achieved without any limiting next day cognitive effects. The data from the APD125 Phase 2 study are consistent with Phase 1 data and support further development of APD125 for the treatment of insomnia patients who have difficulty maintaining sleep.

"APD125 clearly has robust sleep maintenance properties," according to Dr. Thomas Roth of Henry Ford Hospital, who interpreted the polysomnography data for the Phase 2 trial. "In the trial, APD125 consolidated sleep in ways that are not accomplished by any currently available drug."

The Phase 2 trial of APD125 was a randomized, double-blind, placebo- controlled study evaluating the safety and efficacy of nighttime dosing in patients with chronic insomnia. The trial evaluated standard measurements of sleep, such as wake after sleep onset (WASO), wake time during sleep (WTDS), number of awakenings, number of arousals, total sleep time and latency to persistent sleep, and enrolled a total of 173 male and female patients in about 25 clinical sites in the United States. The trial employed a cross-over design: every pa
'/>"/>

SOURCE Arena Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... Ind. , March 30, 2015  Zimmer ... today that the European Commission ("EC") has conditionally ...  The EC,s clearance is conditioned upon Zimmer entering ... certain assets comprising the remedy package previously submitted ... such agreements in the near term.  As previously ...
(Date:3/30/2015)... 25, 2015 Research and Markets ( ... "Global Healthcare Cloud Computing Market 2015-2019" report to ... Healthcare Cloud Computing market to grow at a CAGR ... Increased adoption of IT in healthcare has led to ... the Global Healthcare industry. Though there are significant challenges ...
(Date:3/30/2015)... 2015  The future of cancer care with ... analytics; new, more precise methods for delivering stereotactic ... techniques.  Some 150 researchers from leading clinics around ... a symposium on research funded by Varian Medical ... "Researchers are developing, testing, and validating new innovations, ...
Breaking Medicine Technology:Zimmer Announces Clearance by the European Commission of the Pending Biomet Merger 2Zimmer Announces Clearance by the European Commission of the Pending Biomet Merger 3Zimmer Announces Clearance by the European Commission of the Pending Biomet Merger 4Zimmer Announces Clearance by the European Commission of the Pending Biomet Merger 5Global Healthcare Cloud Computing Market 2015-2019 with Agfa, CareCloud, Carestream Health, Cisco, ClearData Networks, Dell, GE & Merge Healthcare Dominating 2Radiation Oncology Researchers Glimpse the Future of Cancer Care 2Radiation Oncology Researchers Glimpse the Future of Cancer Care 3Radiation Oncology Researchers Glimpse the Future of Cancer Care 4Radiation Oncology Researchers Glimpse the Future of Cancer Care 5Radiation Oncology Researchers Glimpse the Future of Cancer Care 6
(Date:3/30/2015)... (PRWEB) March 30, 2015 “ iCareTech ” ... Report, which takes a look at the latest and coolest ... NewsWatch special reporter and technology expert, conducted the review and ... band that’s dedicated to the medical and health fields. , ... of conversation over the past couple of years. Well, at ...
(Date:3/30/2015)... 30, 2015 According to a recently ... hernia repair market will continue to dominate the European ... primarily due to increasing numbers of ventral hernias, and ... , “The significantly large market share represented by ventral ... ASP. We’re seeing a growing use of expensive biologics,” ...
(Date:3/30/2015)... 30, 2015 Follow us on ... to develop and establish chronic pain rehabilitation centers are ... the market is poised to benefit from the rise ... the increase in chronic health conditions such as Cancer, ... among others. While conventional treatment for pain management is ...
(Date:3/30/2015)... March 30, 2015 Dr. Shahdad ... Invisalign. Eligible patients will receive $200 off their Invisalign ... particularly interested in wearing a mouthful of metal. Invisalign ... use of traditional braces is effective for straightening teeth ... already concerned with their oral appearance. The Invisalign system ...
(Date:3/30/2015)... Slidezilla, an app from the makers ... that innovates the fun and simplicity of photo slideshows. ... photo slideshows and then instantly share them across their ... wanted to create a slideshow app where users can ... fun options to personalize them. You can choose your ...
Breaking Medicine News(10 mins):Health News:World’s First Medical Intelligent Band was Featured on NewsWatch Television on January 30, 2015 2Health News:High Prices for Advanced Biologic Hernia Repair Technology Driving European Soft Tissue Reinforcement and Regeneration Market Growth 2Health News:High Prices for Advanced Biologic Hernia Repair Technology Driving European Soft Tissue Reinforcement and Regeneration Market Growth 3Health News:Technological Developments, Better Patient Awareness & Affordability Drive the Pain Management Devices Market, According to a New Report by Global Industry Analysts, Inc. 2Health News:Technological Developments, Better Patient Awareness & Affordability Drive the Pain Management Devices Market, According to a New Report by Global Industry Analysts, Inc. 3Health News:Northridge Cosmetic Dentist, Dr. Arami, is Now Offering a New Promotion on Invisalign 2
... and Emcure Pharmaceuticals Ltd, a Pune-based company have jointly ... of hypertension. Announcing this at a press conference here ... Satish Mehta said the chirally pure S-Amlodipine, a product ... for the patients suffering from hypertension. ,Stating ...
... that has receive only a little scientific interest and virtually ... and respiratory health. A study of over 2,000 children ... issue. The study appeared in the January 15, 2002 ... and potassium intakes were associated with lower lung function. ...
... research from Australian company has finalized development of ... the guesswork out of diagnosing melanomas, the third ... director of Polartechnics said that in terms of ... specialists.// ,Image analysis and computer-aided diagnostic software ...
... red wine drinkers have increased HDL cholesterol, commonly referred ... light on why red wine is believed to be ... cholesterol levels between 40 men who drink every now ... who are heavy drinkers. As alcohol consumption shot up, ...
... University of Michigan, made a new study which ... head and neck surgery. Ann Arbor say leeches are an ... surgery// to remove cancer in and around the head and ... say about 15 percent of patients develop obstructions that cannot ...
... is able to differentiate those who will get Alzheimer's disease ... of older people - so we can expect an increase ... are now available and they seem to work best if ... ,Researchers at the University of Toronto have been ...
Cached Medicine News:Health News:Latest device for identifying Melanomas 2
... 16 electrodes with ball joint, and flexible wire ... assembly, with 16 female support for ball joint of ... individual electrodes with flexible wire and carbon tip. ... skull. Mounting post. Key to ...
... synergy T-EP Developed in collaboration with ... and an exceptionally high standard of ... Multimedia technology and design expertise to ... 2, 5 or 10-channel Medelec Synergy ...
Neuropack MEB-2200 evoked potential/EMG measuring system is user friendly Windows NT, Pentium III PC-based EP/EMG measuring system....
Sierra II power & efficiency plus. Sierra II report generator with automatic sentence generation creates the one-minute report. Complete 2/4 channel EMG/NCV/EP....
Medicine Products: