Navigation Links
Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance
Date:3/12/2010

-chron">February 2010, we announced the appointment of Felix J. Baker, Ph.D. to our Board of Directors. Dr. Baker is a managing partner of Baker Bros. Advisors, LLC, the manager and advisor to the funds of Baker Brothers Investments, Ardea's largest stockholder.
  • In January 2010, we announced positive results from the second dosing cohort of a completed Phase 2a, proof-of-concept study evaluating the serum urate (sUA) lowering effect, safety and tolerability of combining RDEA594 and allopurinol in gout patients with hyperuricemia (mean sUA level of 10.2 mg/dL). The combination of RDEA594 and allopurinol reduced sUA levels an additional 24 percent compared to allopurinol alone, and resulted in a 100 percent treatment response rate. The combination of RDEA594 and allopurinol in gout patients was well tolerated.
  • Also in January 2010, we announced positive results from the second panel of a Phase 1 drug-drug interaction and pharmacodynamic study of RDEA594 in combination with febuxostat (Uloric®, Takeda Pharmaceutical Company Limited; Adenuric®, Ipsen and Menarini), in healthy volunteers with a mean sUA level of 7.0 mg/dL. The combination of RDEA594 with febuxostat resulted in approximately a 70 to 80 percent mean reduction in sUA levels compared to baseline, reaching mean sUA levels of 1.2 mg/dL. The combination of RDEA594 and febuxostat was well tolerated, with Grade 2 elevations of liver enzymes associated with febuxostat treatment as the only significant laboratory abnormalities.

  • Clinical Development Efforts and Important Upcoming Clinical Development Milestones'/>"/>

    SOURCE Ardea Biosciences, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8 9 10 11

    Related medicine technology :

    1. Ardea Biosciences, Inc. Announces Completion of Phase 1 Clinical Trials of Novel Investigational HIV Drug RDEA806
    2. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
    3. Ardea Biosciences Lead MEK Inhibitor, RDEA119, to Enter Human Clinical Trials in Advanced Cancer Patients
    4. Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout
    5. Ardea Biosciences Presents Preclinical Data Demonstrating Favorable Resistance Profiles for Non-Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Human Immunodeficiency Virus
    6. Ardea Biosciences Reports Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating up to 2.0 Log Reduction in Plasma Viral Load
    7. Ardea Biosciences Presents Data Demonstrating Favorable Pharmacokinetics and Efficacy for Mitogen-Activated ERK Kinase (MEK) Inhibitors
    8. Ardea Biosciences Appoints John W. Beck Chief Financial Officer, Announces Clinical Development Progress and Reports First Quarter 2008 Financial Results
    9. Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594
    10. Ardea Biosciences Presents Preclinical Data on RDEA119 Demonstrating Favorable Anti-Inflammatory Profile for Potential Use in Ulcerative Colitis
    11. Ardea Announces Progress with HIV Non-Nucleoside Reverse Transcriptase Inhibitor Program
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/29/2014)... ROCKVILLE, Md. , July 29, 2014  Synthetic ... anti-infective biologic and drug candidates targeting specific pathogens that ... view of the unusual market activity in the Company,s ... Company in accordance with its usual practice. The Company ... unusual market activity. About Synthetic Biologics, Inc. ...
    (Date:7/29/2014)... -- New high priced hepatitis C drugs will increase ... $2.9 to $5.8 billion next year, according to a ... by the Pharmaceutical Care Management Association (PCMA). Milliman projects ... much as 8.6 percent in 2015 as a result ... The study finds that the majority of ...
    (Date:7/29/2014)... ALBANY, New York , July 29, 2014 /PRNewswire/ ... published by Transparency Market Research "Surgical Navigation Systems Market ... Systems) - Global Industry Analysis, Size, Share, Growth, Trends ... systems market was valued at USD 218.5 million in ... of 4.5% from 2014 to 2020, to reach an ...
    Breaking Medicine Technology:Synthetic Biologics, Inc. States that Its Policy is Not to Comment on Unusual Market Activity 2New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2Surgical Navigation Systems Market Expected to Reach USD 295.5 Million Globally in 2020: Transparency Market Research 2Surgical Navigation Systems Market Expected to Reach USD 295.5 Million Globally in 2020: Transparency Market Research 3Surgical Navigation Systems Market Expected to Reach USD 295.5 Million Globally in 2020: Transparency Market Research 4
    (Date:7/29/2014)... (PRWEB) July 29, 2014 Outsourced ... of tripling in the number of hospitals contracting ... 1, 2015 deadline, according to the recently published ... physician leaders, found in the reports “Top Ranked ... hospitals now outsource Clinical documentation audit, review and ...
    (Date:7/29/2014)... million this year to support innovative research on ... that affect more than 233,000 Canadians. , ... across Canada. This diverse research will explore genetic ... understanding (and potential treatment) of symptoms and consider ... life. , Crohn,s and Colitis Canada funds ...
    (Date:7/29/2014)... 29, 2014 CHI-California Healthcare Institute today ... the hepatitis C (hep C) epidemic in the U.S., ... treatments to reduce human suffering. The report examines key ... of hep C, while highlighting the significance of breakthroughs ... treatment. CHI is a nonprofit, public policy research organization, ...
    (Date:7/29/2014)... Dennis Thompson HealthDay Reporter ... deadly Ebola virus that continues to rage throughout West Africa ... Ebola only spreads through physical touch, and it can,t ... Stephan Monroe, deputy director of the National Center for Emerging ... Control and Prevention, explained in a Monday afternoon news conference. ...
    (Date:7/29/2014)... and aptitudes of Vietnam War veterans who suffered penetrating ... and beginning to answer -- longstanding questions about how ... regions that contribute to optimal social functioning also are ... finding bolsters the view that general intelligence emerges from ... , The findings are reported in the ...
    Breaking Medicine News(10 mins):Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 2Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 3Health News:Prestigious Crohn's and Colitis Canada grants fund promising Canadian research 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 3Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 4Health News:CDC Downplays Ebola's Threat to the United States 2Health News:CDC Downplays Ebola's Threat to the United States 3Health News:CDC Downplays Ebola's Threat to the United States 4Health News:Team studies the social origins of intelligence in the brain 2Health News:Team studies the social origins of intelligence in the brain 3
    ... , TUESDAY, May 3 (HealthDay News) -- ... the filling station, but research from Mississippi has ... go down -- even ones because of drunken driving ... results suggest that prices have both short-term and intermediate-term ...
    ... A new study from Rhode Island Hospital has ... infections due to Staph aureus in hospitalized adults are ... points out the substantial medical burden that arises from ... of such catheters used in hospitalized patients. The study ...
    ... to be a major health issue in the United ... University of Cincinnati (UC) provides evidence that current prevention ... even need expansion to include more of the population, ... The findings are published in the May 3, ...
    ... and their U.S.-born children gain more than a new ... availability of cheap, convenient, fatty American foods and large ... pounds, approaching U.S. levels of obesity within 15 years ... simply the abundance of high-calorie American junk food that ...
    ... of international experts are set to develop a pioneering tool ... pulmonary disease (COPD) as part of a new EU project. ... month (May 2011), will create computed and physical models of ... how patients might react to different treatments. The ...
    ... normal-weight people with belly fat and heart disease have an increased ... a large, new study reports. A "beer belly" or "muffin ... of cigarettes a day or having very high blood cholesterol, the ... That spare tire is even more significant than your overall body ...
    Cached Medicine News:Health News:Peripheral venous catheters pose infection risk 2Health News:Screening for hepatitis B may be cost-effective for more of the population, analysis shows 2Health News:Screening for hepatitis B may be cost-effective for more of the population, analysis shows 3Health News:'Fatting in': Immigrant groups eat high-calorie American meals to fit in 2Health News:'Fatting in': Immigrant groups eat high-calorie American meals to fit in 3Health News:Virtual lung models set to personalize asthma and COPD treatment 2Health News:Belly Fat + Heart Disease Can Be Deadly: Study 2
    ... an automatic petri dish streaking machine. ... up to 180 pre inoculated petri ... in substantial cost savings. The ISOPLATER® ... standardizes streaking procedures and increases safety ...
    Data review and analysis is carried out with the Acquidata Uromac software already supplied with Acquidata Uromac Lab based urodynamics systems...
    A compact mobile System Cart gives mobility within your department. The cart accomodates the Uromac Median data processor, desktop computer, printer and provides stowage space. Patient related transd...
    ... for any clinical setting, offering an ... UDS procedure. Customize Delphis™ to your ... a Pocket PC, a Touchpad PC ... wireless technology allows you to focus ...
    Medicine Products: