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Ardea Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Date:11/11/2010

thcare on this important new targeted therapy."

Poster presentation details are as follows:Poster Title:

A Multi-Center Phase 1, Dose-Escalation Trial to Determine the Safety and Pharmacokinetics/Pharmacodynamics of BAY 86-9766 (RDEA119), a MEK Inhibitor, in Advanced Cancer PatientsAbstract:

#368Date/Time:

Thursday, November 18, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Ardea Biosciences, Inc.)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) and with Erlotinib for the Treatment of Non-Small Cell Lung CancerAbstract:

#138Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119), a Promising Approach for the Treatment of Colorectal CancersAbstract:

#140Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) Shows Anti-Tumor Efficacy in Mono- and Combination Therapy in Models of Hepatocellular Carcinoma and Pancreatic CancerAbstract:

#151Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)About Ardea Biosciences, Inc.Ardea Biosciences, Inc., of San Diego, California, is a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases.  RDEA594, our lead product candidate for the chronic management of hyperuricemia and gout, is a once-daily, oral inhibitor of the URAT1 transporter inhibitor in Phase 2 clinical development.  Our next-generation URAT1 inhibitor program is currently in preclinical development.  BAY 86-9766, formerly known as RDEA119, is a potent and specific inhibitor of mitogen-activated ERK
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SOURCE Ardea Biosciences, Inc.
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