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Ardea Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Date:11/11/2010

thcare on this important new targeted therapy."

Poster presentation details are as follows:Poster Title:

A Multi-Center Phase 1, Dose-Escalation Trial to Determine the Safety and Pharmacokinetics/Pharmacodynamics of BAY 86-9766 (RDEA119), a MEK Inhibitor, in Advanced Cancer PatientsAbstract:

#368Date/Time:

Thursday, November 18, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Ardea Biosciences, Inc.)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) and with Erlotinib for the Treatment of Non-Small Cell Lung CancerAbstract:

#138Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119), a Promising Approach for the Treatment of Colorectal CancersAbstract:

#140Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) Shows Anti-Tumor Efficacy in Mono- and Combination Therapy in Models of Hepatocellular Carcinoma and Pancreatic CancerAbstract:

#151Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)About Ardea Biosciences, Inc.Ardea Biosciences, Inc., of San Diego, California, is a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases.  RDEA594, our lead product candidate for the chronic management of hyperuricemia and gout, is a once-daily, oral inhibitor of the URAT1 transporter inhibitor in Phase 2 clinical development.  Our next-generation URAT1 inhibitor program is currently in preclinical development.  BAY 86-9766, formerly known as RDEA119, is a potent and specific inhibitor of mitogen-activated ERK
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SOURCE Ardea Biosciences, Inc.
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4. Ardea Biosciences Reports Recent Accomplishments and Announces Third Quarter and Year-to-Date 2009 Financial Results
5. Ardea Biosciences Presents Preclinical Anti-Inflammatory Data on its Lead MEK Inhibitor, RDEA119, at the ACG 2008 Annual Meeting
6. Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting
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