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Ardea Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Date:11/11/2010

thcare on this important new targeted therapy."

Poster presentation details are as follows:Poster Title:

A Multi-Center Phase 1, Dose-Escalation Trial to Determine the Safety and Pharmacokinetics/Pharmacodynamics of BAY 86-9766 (RDEA119), a MEK Inhibitor, in Advanced Cancer PatientsAbstract:

#368Date/Time:

Thursday, November 18, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Ardea Biosciences, Inc.)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) and with Erlotinib for the Treatment of Non-Small Cell Lung CancerAbstract:

#138Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Combination of PI3K Inhibitor BAY 80-6946 with Allosteric MEK Inhibitor BAY 86-9766 (RDEA119), a Promising Approach for the Treatment of Colorectal CancersAbstract:

#140Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)Poster Title:

Allosteric MEK Inhibitor BAY 86-9766 (RDEA119) Shows Anti-Tumor Efficacy in Mono- and Combination Therapy in Models of Hepatocellular Carcinoma and Pancreatic CancerAbstract:

#151Date/Time:

Wednesday, November 17, 2010 from 12:00 PM – 2:40 PM CET(Submitted by Bayer HealthCare AG)About Ardea Biosciences, Inc.Ardea Biosciences, Inc., of San Diego, California, is a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases.  RDEA594, our lead product candidate for the chronic management of hyperuricemia and gout, is a once-daily, oral inhibitor of the URAT1 transporter inhibitor in Phase 2 clinical development.  Our next-generation URAT1 inhibitor program is currently in preclinical development.  BAY 86-9766, formerly known as RDEA119, is a potent and specific inhibitor of mitogen-activated ERK
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SOURCE Ardea Biosciences, Inc.
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Related medicine technology :

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2. Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance
3. Ardea Biosciences to Present at Two Upcoming Investor Conferences
4. Ardea Biosciences Reports Recent Accomplishments and Announces Third Quarter and Year-to-Date 2009 Financial Results
5. Ardea Biosciences Presents Preclinical Anti-Inflammatory Data on its Lead MEK Inhibitor, RDEA119, at the ACG 2008 Annual Meeting
6. Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting
7. Ardea Biosciences Advances Lead Product Candidate for the Treatment of Gout, RDEA594, Into Phase 1 Clinical Trial
8. Ardea Biosciences Presents Phase 2a Antiviral Activity Data for Lead HIV Candidate, RDEA806 at XVII International AIDS Conference
9. Ardea Biosciences Reports Additional Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating Up to 1.9 Log Reduction in Plasma Viral Load with Once-Daily Dosing
10. Ardea Announces Progress with HIV Non-Nucleoside Reverse Transcriptase Inhibitor Program
11. Ardea Biosciences Presents Preclinical Data on RDEA119 Demonstrating Favorable Anti-Inflammatory Profile for Potential Use in Ulcerative Colitis
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