Arcion Therapeutics' Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic ... (s applied to both feet twice daily for t...)

Arcion Therapeutics' Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic Neuropathy

Date:5/7/2009

s applied to both feet twice daily for the first two weeks and three times a day for six weeks. Participants rated their pain throughout the study.

About Painful Diabetic Neuropathy (PDN)

Diabetic neuropathy is one of the most common complications of diabetes mellitus that is associated with a number of painful conditions. According to 2008 estimates by the Centers for Disease Control and Prevention, nearly 24 million people in the United States are affected by diabetes. Given a conservative estimate that 15% of people with diabetes have painful neuropathies, approximately 3.6 million Americans experience PDN. PDN is thought to result from chronic hyperglycemia, which can lead to diabetic microvascular injury involving small blood vessels that supply nerves (vasa nervorum), particularly the sensory, motor and autonomic nerve fibers. Patients with PDN often experience debilitating pain symptoms that affect day-to-day functioning and quality of life.

About Arcion

Arcion Therapeutics applies breakthroughs in neuroscience to advance the treatment of chronic pain. The company focuses on innovative topical treatments to provide pain relief with convenient application and reduced systemic side effects. Arcion's product pipeline comprises multiple candidates to treat neuropathic pain.

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