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Archimedes Pharma Launches Lazanda® - the Only Fentanyl Nasal Spray for the Management of Breakthrough Pain in Cancer in the U.S.
Date:10/17/2011

READING, England and BEDMINSTER, N.J., Oct. 17, 2011 /PRNewswire/ -- Archimedes Pharma Ltd., and its subsidiary, Archimedes Pharma U.S. Inc., today announced that Lazanda® (fentanyl) nasal spray is now available by prescription in U.S. pharmacies.  Lazanda is indicated for the management of breakthrough pain in cancer patients 18 years of age and older who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain. The U.S. Food and Drug Administration approved Lazanda on June 30, 2011, marking the first product approval for Archimedes Pharma in the U.S. and the first fentanyl nasal spray in the U.S.

Breakthrough pain, experienced by more than half of patients with cancer who have pain, can be debilitating to  patients and interfere with their ability to engage in daily living activities. Different from the constant background pain many patients with cancer experience, breakthrough pain is described as an intense, excruciating pain with rapid onset and relatively short duration, which occurs despite taking appropriate opioid therapy for background pain."Even though the incidence of breakthrough pain is high in cancer patients, it is often not correctly identified nor reported," said Nash Gabrail, MD, MRCP, of the Gabrail Cancer Center and clinical investigator for Lazanda.  "If reported, it is typically managed by either increasing the dose of background opioids or giving an additional dose of a short-acting oral opioid – neither of which is optimal therapy.  Lazanda, with its rapid and controlled availability, can provide pain relief with an onset of action and duration of effect that addresses the time course of a typical breakthrough pain episode."

Lazanda uses Archimedes' patented PecSys® drug delivery system, which allows the active ingredient to be rapidly absorbed across the nasal membrane and directly into the blood stream. Lazanda is marketed as
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SOURCE Archimedes Pharma Ltd.
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