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Antibody Drug Conjugates Market (2nd Edition), 2014 - 2024
Date:9/1/2014

and Cytotoxins
3.2.1. Naked Antibodies
3.2.1.1. How Monoclonal Antibody Therapy Works
3.2.2. Cytotoxins
3.3. Conjugated or Armed Antibodies
3.4. The Revolutionary Technology: ADCs
3.5. Advantages of ADC over Traditional Therapeutics
3.6. Parts of an ADC
3.6.1. Antibody
3.6.2. Cytotoxin
3.6.3. Linker: Function and Types

4. ADC THERAPEUTICS: OVERVIEW AND BACKGROUND
4.1. Chapter Overview
4.2. Kadcyla Becomes the Third ADC to Reach Market
4.2.1. Mylotarg (Pfizer)
4.2.1.1. Mechanism of Action
4.2.1.2. Approval and Discontinuation of Mylotarg in the US
4.2.1.3. Reasons for Poor Clinical Benefits of Mylotarg
4.2.2. Adcetris (Seattle Genetics/Takeda Oncology Company)
4.2.3. Kadcyla (Roche/Genentech)
4.3. Companies Active in the ADC Market
4.3.1. Large Pharmaceutical Companies Taking Interest
4.4. Companies Providing ADC Technology
4.5. Role of Venture Capitalists
4.6. Analysis of the Development Pipeline
4.6.1. Limited Number of Molecules in Late Stage Development
4.6.2. Cancer is the Leading Indication, with ADCs Against Blood Cancer Dominating
4.7. Commonly Used Cytotoxins in ADC
4.7.1. Cytotoxins Used in ADCs are Highly Potent APIs
4.7.2. Auristatins are the Most Commonly Used Cytotoxins
4.8. Linker: Function and Types
4.8.1. Manufacturing of Linkers
4.8.2. ADC Market by Type of Linker

5. ADC MARKET FORECAST, 2014 - 2024
5.1. Chapter Overview
5.2. ADC Market, 2013
5.2.1. Adcetris and Kadcyla were the Sole Participant in the Market in 2013
5.3. Overall ADC Market Forecast, 2014-2024
5.3.1. Scope and Limitations
5.3.2. Forecast Methodology
5.3.3. The ADC Drug Sales Market, 2014 - 2024
5.3.3.1. Overall Sales Forecast, 2014 - 2024: By Type of ADC
5.3.3.2. Overall Sales Forecast, 2014 - 2024: By Type of Linker
5.3.3.3. Overall Sales Forecast, 2014 - 2024: By Type of Cytotoxin

5.4. Adcetris (S
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