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Anthera Pharmaceuticals Selects the Merck BioManufacturing Network as Manufacturing Supplier for A-623, Anthera's Investigational Novel Peptibody Agent
Date:12/14/2010

y to Evaluate the Efficacy, Safety, and Tolerability of A623 AdministRation in Subjects with Systemic Lupus Erythematosus), is designed to demonstrate that inhibition of both membrane bound and soluble BAFF with A-623 will improve patient clinical outcomes as measured by a composite SLE responder index. Lupus patients suffer from an inappropriate, chronic autoimmune response which often leads to severe skin rash, fatigue, joint pain, organ complications and cardiovascular disease.

About B-Cell Activating Factor (BAFF) and A-623

BAFF has been associated with a wide range of B-Cell mediated autoimmune diseases, including systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, Sjogren's Syndrome, Graves' Disease and others. Multiple clinical studies with other BAFF antagonists recently have reported on BAFF's potential positive role in treating lupus and rheumatoid arthritis. Anthera is advancing its development of A-623, a broad inhibitor of BAFF, to expand its potential clinical utility in autoimmune diseases. A-623 is a novel fusion protein called a peptibody and is distinct from an antibody. Anthera owns worldwide rights to A-623 in all potential indications.

About Merck BioManufacturing Network

Merck BioManufacturing Network (known outside the USA and Canada as MSD BioManufacturing Network) is a full service CMO providing development and manufacturing services for biologics to pharmaceutical and biotechnology companies. It comprises the operations at Billingham, UK (formerly Avecia Biologics), and at Research Triangle Park, NC, USA (formerly Diosynth Biotechnology). Merck is known as MSD outside USA and Canada. For additional information about Merck BioManufacturing Network, please visit www.biomanufacturingnetwork.com.

About Anthera Pharmaceuticals

Anthera Pharmaceuticals is a biopharmaceutical company foc
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SOURCE Anthera Pharmaceuticals, Inc.
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