Navigation Links
Anthera Announces the Advancement of Blisibimod into Phase 3 Development for Patients with Systemic Lupus Erythematosus (SLE)
Date:9/17/2012

ematosus Response Index (SRI*) including the requirement of an eight-point or greater improvement from baseline in the SELENA/SLEDAI disease measurement (SRI-8).

"The use of an SRI-8 endpoint, in a population with higher baseline disease activity requires patients to demonstrate improvement in the clinical presentations of SLE, such as skin, mucosal, joint disease and kidney disease," said Colin Hislop, Anthera's Chief Medical Officer.  "For example, the blisibimod 200 mg weekly dose reduced proteinuria by nearly 1 gram per 24 hours at Week 24 compared with minimal change in the placebo group.  This corresponds to an approximate 50% decrease from baseline. These types of improvements were responsible for the majority of clinical benefits seen in the PEARL-SC study and highlights blisibimod's potential to help patients with more active disease."

As previously reported, results from the PEARL-SC study indicate that in the predefined population of patients with clinically active disease (SELENA-SLEDAI > 10) who were also taking corticosteroids, the SRI-8 treatment benefit in the 200 mg weekly blisibimod cohort was statistically significant at week eight (22.6% blisibimod response versus 6.4% placebo response, p=0.023) and at week 16 (35.4% blisibimod response versus 17.0% placebo response, p=0.04) through the 24 week endpoint (41.7% blisibimod response versus 10.4% placebo response, p<0.001). Results from the PEARL-SC clinical study have been submitted to the American College of Rheumatology for presentation at the ACR/ARHP Annual Scientific Meeting 2012 in Washington, D.C.

*SRI is defined as patients who respond to treatment and achieve a reduction in SELENA-SLEDAI equal to or greater than the number indicated, no new BILAG A or two B organ domain scores, and no increase in Physician's Global Assessment (PGA) of greater than 0.3 on a three point scale.

About Anthera Pharmaceuticals

Anthera Pharmaceuticals
'/>"/>

SOURCE Anthera Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Anthera Pharmaceuticals Reports 2012 Second Quarter Financial Results And Provides Clinical Progress Update
2. Anthera Pharmaceuticals Announces Exercise in Full of Over-Allotment Option and Completion of Public Offering of Common Stock
3. Anthera Pharmaceuticals Announces Pricing of Public Offering of Common Stock
4. Anthera Pharmaceuticals Announces Proposed Public Offering of Common Stock
5. Anthera Pharmaceuticals Provides Additional Data from the Recently Completed PEARL-SC Study of Blisibimod in the Proposed Phase 3 Population
6. Anthera Pharmaceuticals to Present at the 7th Annual JMP Securities Healthcare Conference
7. Anthera Updates Phase 3 Plans Following Results from the Phase 2b PEARL-SC Dose Ranging Study of Blisibimod
8. Anthera Pharmaceuticals Reports 2012 First Quarter Financial Results And Provides Clinical Progress Update
9. Anthera Announces First Quarter 2012 Financial Report and Conference Call
10. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
11. Merz, Inc. Announces Cynthia Schwalm as Vice President, Neurology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... UBM Medica US announces that Neurology Times ... for neurologists and other healthcare providers, features special coverage on ... discussions of the latest developments in approaches to diagnosis. ... , more than the total of those who have multiple ... can be difficult because there are no confirmatory medical tests. ...
(Date:10/17/2014)... -- A victim of medical negligence at the hands of ... history of alcohol abuse, a physician and consumer advocates unveiled ... highlighting how Prop 46 will identify and deter physician substance ... The ad pictures a doctor drinking at a bar as ... will enact the first law in the nation requiring random ...
(Date:10/17/2014)... InnFocus, Inc ., reported on results of 59 glaucoma patients ... up to 3 years with the InnFocus MicroShunt® at the ... . The Summit was held ... American Academy of Ophthalmology . The Company also said ... 6 countries by early 2015. Logo - ...
Breaking Medicine Technology:Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 2Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 4InnFocus Featured at the Ophthalmology Innovation Summit In Chicago 2
... June 1, 2010 MediSapiens, world,s first,software company for personalized cancer ... ( EUR 0.8 million ) seed round,investment from Veraventure, ETFIII advised by ... , , ... at the VTT Technical Research,Centre of Finland and its collaborators. ...
... TEL AVIV, Israel , May 31, 2010 ... for the first,quarter of 2010. , , ... Loss for the first quarter of 2010 attributable to the ... minority interest,totaled to NIS 170 million ), as compared to gain attributable ...
Cached Medicine Technology:MediSapiens Gets $ 1 Million for World's First Personalized Cancer Medicine Software 2MediSapiens Gets $ 1 Million for World's First Personalized Cancer Medicine Software 3MediSapiens Gets $ 1 Million for World's First Personalized Cancer Medicine Software 4Elbit Imaging Ltd. Announces First Quarter Results for 2010 2Elbit Imaging Ltd. Announces First Quarter Results for 2010 3Elbit Imaging Ltd. Announces First Quarter Results for 2010 4Elbit Imaging Ltd. Announces First Quarter Results for 2010 5Elbit Imaging Ltd. Announces First Quarter Results for 2010 6Elbit Imaging Ltd. Announces First Quarter Results for 2010 7Elbit Imaging Ltd. Announces First Quarter Results for 2010 8Elbit Imaging Ltd. Announces First Quarter Results for 2010 9Elbit Imaging Ltd. Announces First Quarter Results for 2010 10Elbit Imaging Ltd. Announces First Quarter Results for 2010 11Elbit Imaging Ltd. Announces First Quarter Results for 2010 12
(Date:10/20/2014)... hc1.com today announced the launch ... that enables healthcare organizations of all sizes to ... relationship management (“CRM”) solution. , Designed from the ... the healthcare industry, the hc1 Healthcare Relationship Cloud™ ... by combining healthcare CRM, HIPAA-compliant collaboration, and real-time ...
(Date:10/20/2014)... Angeles, CA (PRWEB) October 20, 2014 ... fitness expertise, nutritional coaching, corporate wellness programming, authorship, international ... CPT, is excited to announce the release of the ... , After many years of coaching thousands of individuals ... nutrition tracking app that does not require calorie counting ...
(Date:10/20/2014)... October 20, 2014 Principle Business Enterprises, ... pride in manufacturing top-of-the-line absorbent products. The company ... its most popular brand, Tranquility® Premium Protection absorbent products. ... new website, gave its packaging a new look, and ... brand message to the public. , The new website, ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 ... Voicheck as Assistant Director of their CentralSource ... in managing the innovative turnkey drug sourcing, distribution, ... Matthew brings over 12 years of industry experience, ... Myoderm at the peak of their international success ...
(Date:10/20/2014)... Succeed is proud to announce that they ranked in the ... Every Body Walk! campaign by Kaiser Permanente. Every ... to be more active outside of the workplace. This ... end of September, was a friendly competition between organizations across ... companies gave their staff pedometers and each day, for the ...
Breaking Medicine News(10 mins):Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:Tranquility® Premium Protection Incontinence Products Releases New Logo and Website 2Health News:Myoderm Hires Matthew Voicheck to Lead Turnkey Drug Sourcing Service 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2
... Ohio, April 7, 2008 Chemical Abstracts,Service (CAS) ... SciFinder research,tool. CAS announced and demonstrated the new ... in New Orleans, April 6, 2008., (Logo: ... find using the new version of SciFinder an,important ...
... Put Medical Equipment Providers Out of Business and,Disrupt Services ... Dallas Area;, Austin, Beaumont, El Paso, Houston, McAllen, ... 7, 2008 A new Medicare,bidding program for durable ... Worth metropolitan area on July 1, 2008, will,put many ...
... finds olanzapine changes metabolism in weeks , , MONDAY, April ... olanzapine may put a person at an increased risk ... show. , A team of French researchers studying the ... olanzapine over several weeks, the rodents, blood sugar ...
... Health Record to actively engage diabetes patients in their ... levels, better vaccination compliance and increased tobacco cessation rates, ... Health System launched an Electronic Health Record-driven care program ... published in Aprils Journal of General Internal Medicine showed ...
... Cons of Approach to Eliminating HAIs, ORLANDO, Fla., ... drive to eliminate infections acquired in hospitals -,is provoking ... the approach is overly simplistic and potentially dangerous to,praise ... experts will,discuss the hot-button issue at the Annual Meeting ...
... The critical lack of,family and paraprofessional caregivers ... renewal of the Community College Caregiver Training,Initiative for ... Foundation, The Caregiving Project for Older,Americans, a project ... a Request for Proposals (RFP) and will award ...
Cached Medicine News:Health News:CAS' New SciFinder(R) Enhances the Research Experience Via the Web 2Health News:Medicare Bidding Program for Dallas, Texas is Rife with Errors, Says American Association for Homecare 2Health News:Medicare Bidding Program for Dallas, Texas is Rife with Errors, Says American Association for Homecare 3Health News:Antipsychotic Drug Boosts Risk of Heart Disease, Diabetes 2Health News:Geisinger improves care for thousands of diabetics through use of the Electronic Health Record 2Health News:The 'Zero' Mentality: Is It Good for Infection Control? 2Health News:ILC-USA and MetLife Foundation Launch Second Year of Community College Caregiver Training Grants 2
3.2 mm Keratome, double bevel, sharp sides, ang. 1 Ea as quantity....
... 50Hz/60Hz is the most powerful isolated ESU on ... Coag. It is the only ESU that allows ... surgical field with a standard ES pencil. Excalibur ... maintains minimum necessary voltage for smooth cutting through ...
Microcontroller-based isolated electrosurgical generator, designed for all general purpose surgical procedures. Unit includes: Instant Response technology, adaptive REM system, isolated output, CEM c...
Lorgnette pinhole occluder...
Medicine Products: