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Another LNA-based RNA Inhibitor Enters Clinical Trials
Date:3/20/2009

s highly effective and efficient drug discovery engine to generate lead LNA drug candidates against a broad array of disease targets selected by strategic partners. Santaris Pharma was founded in 2003 and the Company and its corporate partners currently have four compounds in clinical development and a full pipeline in late preclinical development. Current partners are Enzon Pharmaceuticals, GlaxoSmithKline and Wyeth Pharmaceuticals. Santaris Pharma has since its inception raised nearly $100 million through private financing and up front payments.

About Enzon

Enzon Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to developing, manufacturing and commercializing important medicines for patients with cancer and other life-threatening conditions. The Company has a portfolio of four marketed products, Oncaspar(R), DepoCyt(R), Abelcet(R) and Adagen(R). Enzon's drug development programs utilize several cutting-edge approaches, including its industry-leading PEGylation technology platform and the Locked Nucleic Acid (LNA) technology. Enzon's PEGylation technology was used to develop two of its products, Oncaspar and Adagen, and has created a royalty revenue stream from licensing partner-ships for other products developed using the technology. Enzon also engages in contract manufacturing for several pharmaceutical companies to broaden the Company's revenue base.


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