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Annual FIT Testing Detects Colorectal Cancer Two Years Earlier Than Colonoscopy Alone, Study of High-Risk Population Finds
Date:5/20/2008

and more frequent colonoscopies if polyps are detected or a risk of hereditary nonpolyposis colorectal cancer (HNPCC) is suspected. For patients at average risk over the age of 50, ACS guidelines include colonoscopy every ten years and an annual FIT test among the recommended screening options.(4)

The study was conducted using the InSure(R) FIT(TM) test, a take-at-home annual colorectal cancer screening test from Enterix, Inc., a wholly-owned subsidiary of Quest Diagnostics. InSure FIT, and the recently launched InSure Quik F I T(TM), each use a patient-friendly, long-handled blue brush to collect two water-based samples for analysis. The tests are completed at home, and samples are submitted to a Quest Diagnostics laboratory (InSure FIT) or returned to the physician's office (InSure Quik F I T) for evaluation.

The study presented at Digestive Disease Week was funded by grants from the National Health and Medical Council of Australia and Enterix Australia Pty. Ltd. Enterix was acquired by Quest Diagnostics in September 2006. Neither company participated in the study's data analysis or influenced the conclusions of the researchers.

The study abstract is published in the April 2008 supplement of Gastroenterology.

About Colorectal Cancer

Colorectal cancer is the second leading cause of cancer death in the United States. The American Cancer Society (ACS) estimates nearly 150,000 men and women in the U.S. will be diagnosed with colorectal cancer this year, and one third of these patients will ultimately succumb to the disease.(5) When found early and treated, the five-year relative survival rate for colon cancer is 90 percent(6), yet less than 40 percent of colorectal cancers are found early.(7) Medical experts advise that anyone at age 50 or older at average risk should, as one of their screening options, be screened annually with an FOBT or FIT for this disease. Recent ACS guidelines reinforce recommendations for FIT tests, like the
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SOURCE Quest Diagnostics
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