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Annual Conference on Vaccine Research to Highlight Not Only Health Benefits But Also Economic Gains
Date:5/5/2008

but the University of Pittsburgh approach is the first to make use of non-replicating adenovirus, a common cold virus, as a delivery vehicle to deliver protein from the avian influenza virus into chicken cells. The vaccine, which was injected into the skin of chickens, induced high levels of antibodies that were capable of protecting against infection with several different strains of influenza virus.

The scientists say the genetically engineered vaccine could be produced inexpensively in large quantities for use in chickens and other poultry. If there was an outbreak in humans, the scientists believe the same vaccine could be diverted to protect people from H5N1.

High-dose Influenza Vaccine Benefits the Elderly

Several studies to be presented at the conference indicate that the elderly, who are most at risk of death from influenza, would benefit from high-dose influenza vaccine over standard dosage. One multi-center study, which involved more than 3,800 elderly persons, found significantly greater antibody responses a month after vaccination among those who got high-dose compared to standard-dose vaccine.

The study was conducted by researchers at St. Louis University, the Veteran Affairs Medical Center in St. Louis, the University of Rochester and sanofi pasteur.

About the Annual Conference on Vaccine Research

The Annual Conference on Vaccine Research provides current, high-quality reports of scientific progress featured in both invited presentations and submitted abstracts. The wide range of topics covered in both human and veterinary vaccinology offers a thorough picture of the opportunities, challenges and discoveries associated with vaccine development, production and distribution.

The conference is sponsored by the National Foundation for Infectious Disease (NFID) in collaboration with the Albert H. Sabin Vaccine Institute, Bill & Melinda Gates Foundation, Center for Biologics Evaluation and Research Food and D
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SOURCE National Foundation for Infectious Diseases
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