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Annai Systems And ThoughtWorks Develop Evidence Engine For The Clearity Foundation To Individualize Options For Treatment Of Ovarian Cancer
Date:11/15/2012

SAN DIEGO and LOS GATOS, Calif., Nov. 15, 2012 /PRNewswire/ -- The Clearity Foundation (Clearity) and Annai Systems today announced the implementation of a software-driven system (the MedTrust Evidence Engine-E2) that supports Clearity's mission to individualize treatment options for ovarian cancer patients.  As a result, Clearity is now more efficiently integrating and interpreting data from many sources, including its Diane Barton Database of more than 250 tumor profiles, enabling it to respond to more women who need help in personalizing treatment for their recurrent ovarian cancer.  The MedTrust E2 system was developed by Annai in close collaboration with ThoughtWorks, a global company wholly devoted to the art and science of software development.

Ovarian cancer survival has not improved significantly in decades, largely because of a trial-and-error approach to treating cancer recurrence.  It is now known that ovarian cancer is a heterogeneous disease, and tumors have significantly different characteristics from one patient to the next.  While DNA sequencing, gene expression analysis and other technologies have increasingly made it possible to develop molecular profiles of individual tumors, integrating and interpreting this data and extracting the implications of these profiles for personalized patient care are challenging.  The Clearity Foundation has developed a pro bono service to help patients and their physicians overcome these challenges and to enable more informed decisions about treatment options.  Annai's E2 has automated key steps in the process used by Clearity to deliver this service.  "Clearity can now more efficiently create tumor profiles for our patients and identify personalized treatment options," said Dr. Deborah Zajchowski, Clearity's Scientific Director.   

Hosted by Annai, the MedTrust E2 software system is capable of drawing upon the scientific literature, a wide variety o
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SOURCE The Clearity Foundation; Annai Systems
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