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Anesthesiologists Use Caldolor® To Provide Preemptive Pain Control for Surgical Patients at U.S. Medical Centers
Date:3/2/2011

ing surgery. Reduction in opioid use could reduce opioid-related side effects such as sedation, nausea, vomiting, cognitive impairment and respiratory depression.

William Weisberg, D.O., anesthesiologist and medical director at the Surgery Center at Coral Springs in Coral Springs, Florida, has also seen improved post-surgical outcomes by administering Caldolor to patients at induction of anesthesia. "Initiating Caldolor's analgesic and anti-inflammatory properties prior to surgery minimizes the cascade of pain and inflammation, which is resulting in improved pain relief in the 24 hour period following surgery," said Dr. Weisberg. "This method of addressing pain before it occurs coupled with Caldolor's ability to achieve better pain control than opioids alone translates to less patient pain and a lower requirement for opioids. Our use of opioid rescue in the PACU (post-anesthesia care unit) has decreased, and incorporation of Caldolor into our multi-modal pain management model has led to increased patient satisfaction."

In clinical trials, Caldolor has demonstrated pain relief above and beyond that which was provided by opioids alone, while also reducing opioid use. A published study, entitled "A Multicenter, Randomized, Double-Blind Placebo-Controlled Trial of Intravenous-Ibuprofen (IV-Ibuprofen) for Treatment of Pain in Post-Operative Orthopedic Adult Patients," appeared in the August 2010 edition of the peer-reviewed journal Pain Medicine, and concluded that dosing Caldolor at induction of analgesia as well as post-operatively is effective in treating pain and reducing morphine use in adult patients. This study provides safety and efficacy data supporting use of Caldolor in surgical patients not only during recovery, but also when administered prior to surgery.

"In the practice of acute pain medicine, reducing reliance on opioids is a strategic imperative," said Jonathan S. Jahr, M.D., Co-Editor of The Essence of Analgesia and Analg
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SOURCE Cumberland Pharmaceuticals Inc.
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