Navigation Links
Anemic Patients With MDS Gain Long-Term Benefits From Erythropoietin and Myeloid Growth Factor Hormones
Date:9/17/2009

berg, MD, Professor of Medicine, Stanford University Cancer Center. "Our goal was to manage anemia while not increasing the risk of transformation to leukemia, and we undertook this study to understand if this combination might be successfully utilized in these patients."

The results of the study proved successful for this group of patients with lower-risk MDS and anemia. After the first course of therapy, 36 percent of patients in the EPO arm responded to treatment, compared with only 9.6 percent in the SC alone arm. After subsequent courses, 47 percent responded in the EPO arm. Researchers then followed both patient groups for a median of 5.8 years to determine their long-term response to treatment. Responders to EPO experienced increased survival in comparison to the non-responders (5.5 vs. 2.3 years) and significantly improved physical, emotional, and functional well-being, reduced fatigue, and improved overall quality of life. The research team otherwise found no statistically significant differences in overall survival of patients between the EPO and SC arms (3.1 vs. 2.6 years) or the incidence of transformation to AML (7.5 vs. 10.5 percent of patients, respectively), suggesting long-term safety of the EPO treatment regimen.

The study results also indicated that the combination of EPO plus G-CSF was beneficial for patients who either did not respond initially to EPO or who experienced a delayed response. Furthermore, higher doses of EPO seemed to prove valuable for a proportion of patients who initially failed to respond. Importantly, the outcomes suggested long-term tolerance to the treatment combination, with a low overall incidence of adverse events. Specifically, the researchers found no significant treatment-related increase in incidence of either cardiovascular or thrombotic (clotting) events or transformation to AML in the patients who received EPO alone or with G-CSF, as compared with those in the SC arm.

<
'/>"/>
SOURCE American Society of Hematology
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novel Small Molecule Therapy Shows Benefit for Anemic Patients Via Hydration of Red Blood Cells
2. Lexicon Completes Phase 1 Clinical Trial and Initiates Phase 2 Clinical Trial of LX4211 in Patients With Type 2 Diabetes
3. Alexza Announces Preliminary Results from its AZ-104 (Staccato(R) Loxapine) Phase 2b Trial in Patients with Migraine Headache
4. Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
5. Schering-Plough Reports Long-Term Vicriviroc Data From Phase II Open-Label Extension Study in Treatment-Experienced HIV-Infected Patients
6. Two New Studies Report Increased Survival Rates in Tamiflu(R)-Treated Patients with Avian Flu (H5N1) and Severe Seasonal Flu
7. New Data Show Patients With Chronic Low Back Pain Maintained Pain Reduction on Cymbalta(R)
8. Yoga Benefits Back-Pain Patients
9. Two-Year SYNTAX Data Show Comparable Safety Outcomes for Complex Patients Treated With TAXUS(R) EXPRESS(R) Stents and Bypass Surgery
10. CRESTOR(R) Reduced Risk of Cardiovascular Events in Elderly Patients in New Analysis of Jupiter
11. New Large-Scale, Global Study Provides Additional Information About an Intensified Dose-Regimen of PLAVIX(R) in Acute Coronary Syndrome Patients Undergoing Angioplasty
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Research and Markets ( ... "Investigation Report on China,s Insulin Aspart Market, ... Developed by Novo Nordisk, insulin aspart (under the ... for the treatment of diabetes. Compared with human ... analog, starts working fast and reports higher peak ...
(Date:8/28/2015)... , Aug. 28, 2015  IP Shakti, LLC, today announced ... Logo - ... "Our new corporate identity signifies our transformation into a ... predictive analytics platform for patent claim validity." ... of the proprietary AIA Shield™ platform, the Company commenced a ...
(Date:8/28/2015)... PITTSBURGH , Aug. 28, 2015 /PRNewswire/ ... that its shareholders have approved Mylan,s proposed acquisition ... TASE) and the related issuance of Mylan ordinary ... meeting of shareholders held today. The transaction received ... extraordinary general meeting. In addition, the transaction received ...
Breaking Medicine Technology:China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9
... 25, 2011 The Wound and Hyperbaric ... by the Undersea and Hyperbaric Medical Society (UHMS), the ... that few hospitals and facilities have earned, and identifies ... The super oxygenation offered by hyperbaric treatments can ...
... a privately held medical device company focused on developing ... Aspen™ Spinous Process Fixation System (Aspen) was featured in ... Advanced Spine Techniques (IMAST) in Copenhagen, Denmark, July 13th ... Lanx, commented, "These scientific sessions at IMAST add to ...
Cached Medicine Technology:Good Samaritan Hospital's Wound and Hyperbaric Institute Receives Accreditation from Undersea and Hyperbaric Medical Society, Recognizing Advanced Care 2Good Samaritan Hospital's Wound and Hyperbaric Institute Receives Accreditation from Undersea and Hyperbaric Medical Society, Recognizing Advanced Care 3Lanx, Inc. Announces Aspen™ Spinous Process Fixation System Clinical Data at IMAST 2Lanx, Inc. Announces Aspen™ Spinous Process Fixation System Clinical Data at IMAST 3
(Date:8/28/2015)... ... 28, 2015 , ... Saint Petersburg, FL —Pocket Protein™, a ... carbs, sugar, gluten, lactose or caffeine in a convenient 2 oz. pouch that ... Editor’s Choice Awards. , Five consumer packaged goods (CPG) products were selected by ...
(Date:8/28/2015)... ... August 28, 2015 , ... Altima ... and diagramming network and data center assets and audio-video devices, recently released Visio ... Nexus 5000 Series, HP ProLiant Gen9, EMC VNX Series , Super Micro Computer ...
(Date:8/28/2015)... ... August 28, 2015 , ... Medical Solutions, one of the nation’s largest ... Work in Healthcare by Modern Healthcare and will be honored at an awards ... eighth year, the Best Places to Work in Healthcare program recognizes outstanding employers in ...
(Date:8/28/2015)... ... August 28, 2015 , ... CARF International announced ... residential, counseling, day treatment and intensive family based services. , By pursuing and ... and its pursuit of excellence. As a nonprofit charity for more than 50 ...
(Date:8/28/2015)... Phoenix, Arizona (PRWEB) , ... August 28, 2015 ... ... visibility and increased patient loyalty at a low cost. Personalized with practice contact ... new and existing patients. Dental offices can also incorporate Calendars into seasonal mailings, ...
Breaking Medicine News(10 mins):Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2Health News:SmartPractice® Introduces 2016 Calendars for Dental Practice Giveaways 2
... , BREWER, Maine, Nov. 24 Thanks to an innovative ... Anthem Blue Cross and Blue Shield in Maine, some Anthem ... physician without leaving home. , As part of the ... and questions and communicate via email with their provider about ...
... pediatric cancer and hematology patients in medical rounds benefits ... a new Indiana University School of Medicine study. ... conducted, is now one of only a small number ... cancer and hematology patients the opportunity to join their ...
... ... available to discuss the recently proposed cosmetic surgery tax. , ... Arlington Heights, IL (Vocus) November 24, 2009 ... available to discuss the recently proposed cosmetic surgery tax., , ,WHAT: Some of ...
... strains have increased sevenfold, study finds, , TUESDAY, ... infections normally found in the community are increasingly ... that inpatients could become infected, new research says. ... sevenfold increase in the incidence of outpatients with ...
... New York personal injury ... attorney after a heavy metal piece falls off a plane and lands in a local Long ... New York, NY (PRWEB) ... recent occurrence as a reminder that everyone should have the number of a personal injury attorney ...
... ... seminar series, new ways to train doctors in providing proven, non-surgical relief to millions ... ... ) announced the first three 2010 Frozen Shoulder Syndrome Diagnosis & Treatment seminar ...
Cached Medicine News:Health News:The Doctor Will See You Now. . .Online 2Health News:Involving family in medical rounds benefits both family and medical team 2Health News:Involving family in medical rounds benefits both family and medical team 3Health News:Involving family in medical rounds benefits both family and medical team 4Health News:Leading Plastic Surgery Experts Available to Discuss Proposed ,Cosmetic Surgery Tax 2Health News:MRSA Creeping Into Hospitals From the Outside 2Health News:MRSA Creeping Into Hospitals From the Outside 3Health News:A New York Neighborhood Gets Hit Hard When A Piece Breaks Off A Plane 2Health News:A New York Neighborhood Gets Hit Hard When A Piece Breaks Off A Plane 3Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 2Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 3
... Used for endobronchial ... or right lung for ... ventilation. The set consists ... catheter and an Arndt ...
... a guarded scalpel, introducer, tracheal cannula, neck ... 10fr suction catheter., ,The Mini-Trach® II ... perform a cricothyrotomy., ,With the Mini-Trach® ... mm I.D.) is inserted into the trachea ...
Used for emergency airway access when conventional endotracheal intubation cannot be performed....
... with blade. Rusch offers a reliable tradition ... The designs of these blades have been ... the world over to minimize maintenance requirements. ... the finest surgical grade stainless steel to ...
Medicine Products: