Navigation Links
Anemic Patients With MDS Gain Long-Term Benefits From Erythropoietin and Myeloid Growth Factor Hormones
Date:9/17/2009

berg, MD, Professor of Medicine, Stanford University Cancer Center. "Our goal was to manage anemia while not increasing the risk of transformation to leukemia, and we undertook this study to understand if this combination might be successfully utilized in these patients."

The results of the study proved successful for this group of patients with lower-risk MDS and anemia. After the first course of therapy, 36 percent of patients in the EPO arm responded to treatment, compared with only 9.6 percent in the SC alone arm. After subsequent courses, 47 percent responded in the EPO arm. Researchers then followed both patient groups for a median of 5.8 years to determine their long-term response to treatment. Responders to EPO experienced increased survival in comparison to the non-responders (5.5 vs. 2.3 years) and significantly improved physical, emotional, and functional well-being, reduced fatigue, and improved overall quality of life. The research team otherwise found no statistically significant differences in overall survival of patients between the EPO and SC arms (3.1 vs. 2.6 years) or the incidence of transformation to AML (7.5 vs. 10.5 percent of patients, respectively), suggesting long-term safety of the EPO treatment regimen.

The study results also indicated that the combination of EPO plus G-CSF was beneficial for patients who either did not respond initially to EPO or who experienced a delayed response. Furthermore, higher doses of EPO seemed to prove valuable for a proportion of patients who initially failed to respond. Importantly, the outcomes suggested long-term tolerance to the treatment combination, with a low overall incidence of adverse events. Specifically, the researchers found no significant treatment-related increase in incidence of either cardiovascular or thrombotic (clotting) events or transformation to AML in the patients who received EPO alone or with G-CSF, as compared with those in the SC arm.

<
'/>"/>
SOURCE American Society of Hematology
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novel Small Molecule Therapy Shows Benefit for Anemic Patients Via Hydration of Red Blood Cells
2. Lexicon Completes Phase 1 Clinical Trial and Initiates Phase 2 Clinical Trial of LX4211 in Patients With Type 2 Diabetes
3. Alexza Announces Preliminary Results from its AZ-104 (Staccato(R) Loxapine) Phase 2b Trial in Patients with Migraine Headache
4. Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
5. Schering-Plough Reports Long-Term Vicriviroc Data From Phase II Open-Label Extension Study in Treatment-Experienced HIV-Infected Patients
6. Two New Studies Report Increased Survival Rates in Tamiflu(R)-Treated Patients with Avian Flu (H5N1) and Severe Seasonal Flu
7. New Data Show Patients With Chronic Low Back Pain Maintained Pain Reduction on Cymbalta(R)
8. Yoga Benefits Back-Pain Patients
9. Two-Year SYNTAX Data Show Comparable Safety Outcomes for Complex Patients Treated With TAXUS(R) EXPRESS(R) Stents and Bypass Surgery
10. CRESTOR(R) Reduced Risk of Cardiovascular Events in Elderly Patients in New Analysis of Jupiter
11. New Large-Scale, Global Study Provides Additional Information About an Intensified Dose-Regimen of PLAVIX(R) in Acute Coronary Syndrome Patients Undergoing Angioplasty
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... 2014  CVS Caremark Corporation (NYSE: CVS ... August 5, 2014, at 8:30 a.m. (EDT) with analysts ... results. An audio webcast of the conference ... portion of the CVS Caremark website for all interested ... This webcast will be archived and available on the ...
(Date:7/25/2014)...  Acsis Inc., the market leader for supply ... recently posted an article, "Future of Running ... needs for companies, extended supply chain, and explains ... no longer work today.  The article explains how ... mobile technology, machine to machine (M2M) connectivity, and ...
(Date:7/25/2014)... 2014 Research and Markets has ... Devices Market 2014-2018" report to their offering. ... Ophthalmic Diagnostic Device An ophthalmic diagnostic ... defect or deficiency in the human visual pathway. Ophthalmic ... as presbyopia, cataracts, glaucoma, retinal disorders, conjunctivitis, and dry ...
Breaking Medicine Technology:Acsis Addresses Questions on the Modern Supply Chain 2Global Ophthalmic Diagnostic Devices Market 2014-2018: Key Vendors are Alcon, Carl Zeiss, Haag-Streit and Topcon 2
... 16 Medicare has been touting the merits of the "competitive" bidding program for durable, or home medical equipment ... facts that exaggerate the benefits and ignore the severe shortcomings of the program. , ... ... , ...
... Pharmaceuticals Inc. (Nasdaq: OSIP ) that it will nominate a full and competing slate of independent directors at OSI Pharmaceuticals, 2010 annual stockholders, meeting. , ... , ... ... ...
Cached Medicine Technology:Discussion of Medicare's 'Competitive' Bidding Program for Home Medical Equipment is Plagued by Myths and Misinformation 2Discussion of Medicare's 'Competitive' Bidding Program for Home Medical Equipment is Plagued by Myths and Misinformation 3Discussion of Medicare's 'Competitive' Bidding Program for Home Medical Equipment is Plagued by Myths and Misinformation 4Discussion of Medicare's 'Competitive' Bidding Program for Home Medical Equipment is Plagued by Myths and Misinformation 5Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 2Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 3Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 4Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 5Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 6Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 7Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 8Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 9Astellas Announces Full Slate of Independent Director Nominees for Election at OSI Pharmaceuticals' 2010 Annual Stockholders Meeting 10
(Date:7/28/2014)... 2014 Maternal and Family Health Services ... which will be presented at the agency’s 43rd Annual ... at the Westmoreland Club in Wilkes-Barre. , The late ... long-time employee of MFHS. She dedicated her life ... health advocate, and champion for women, children and families ...
(Date:7/28/2014)... study has found that following a healthy lifestyle may ... syndrome. Published early online in CANCER , a ... indicate that children with cancer and adults who had ... how their lifestyle may influence their long-term health. ... to be at increased risk for the metabolic syndrome, ...
(Date:7/28/2014)... 28, 2014 As health insurers design ... to private exchanges. “Private Exchange Strategies for Insurers: ... from Atlantic Information Services, will provide answers to the ... for the future. , Barbara Gniewek, Jonathan Har-Even and ... experience in the private exchange sector — will provide ...
(Date:7/28/2014)... 28, 2014 Mitul R. Patel, DDS ... at the MGE Management Experts Benefit Dinner May 30, ... joined the Dentists to raise funds for the Improving ... Girls Clubs and Youth Programs across America. The funds ... with books and audio books to directly tackle illiteracy ...
(Date:7/28/2014)... Cuidado Casero , an organization of Medicare certified agencies ... Texas, New Mexico, New Jersey, Virginia, and Puerto Rico, was ... of PAM’s 2014 Gala. , North Texas PAMS is ... Texas chapter was created by a handful of Peruvian physicians ... care for the indigent in Peru. The chapter is developing ...
Breaking Medicine News(10 mins):Health News:MFHS Seeking Nominations for Rose Allan Tucker Award 2Health News:Lifestyle choices may affect the long-term heart health of childhood cancer survivors 2Health News:Three PwC Consultants to Offer Insurers Successful Strategies for Private Exchanges 2Health News:Mitul R. Patel, DDS Successfully Attacks a Major Source of Economic Destruction in the Battle Against Illiteracy and Poverty 2Health News:Mitul R. Patel, DDS Successfully Attacks a Major Source of Economic Destruction in the Battle Against Illiteracy and Poverty 3Health News:Cuidado Casero Sponsors Peruvian American Medical Society (PAMS) Gala 2
... traditional medicinal system, the Indian Council of Medical Research (ICMR) ... develop drugs //from medicinal plants or multi-herb formulations that have ... valid for next five years was signed by ICMR Director ... K Gupta., ,As per the MoU, the ICMR will ...
... shortfall of the tissue culture variety of anti-rabies vaccine, ... of the restricted nerve tissue variety vaccine till the ... minister Surjyakanta Mishra told reporters here today that the ... few years ago citing side-effects., ,"However, since the ...
... shown by an increased nighttime BP than with a traditional ... researchers at Uppsala University revealed that a high blood pressure ... heart failure. ,Congestive heart failure (CHF) is ... Once diagnosed as having CHF, patients have a 1 in ...
... demand for traditional Indian medicine, a four-year degree course ... University (JU) for the first time in eastern India//. ... second of its kind in the country after Gujarat, ... Sciences (BIPS) in joint venture with West Bengal Health ...
... women has shown that those who indulged in six or ... 3 percent reduction in risk of type 2 diabetes, vis ... scientists were not able to place their finger on the ... they strongly feel that the presence of antioxidants and minerals ...
... MMR vaccine has been shrouded in controversy. Now, Britain's reputed ... to the raging //debates over this vaccine. ,Infact they have ... threat to young lives by forsaking the triple shots of ... and the media to defuse the entire furore over the ...
Cached Medicine News:Health News:Increased Nighttime BP, a Significant Predictor of Congestive Heart Failure 2
All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open packages. Intended for one-time use....
Used to provide bladder drainage by percutaneous placement of a balloon catheter. Supplied sterile in peel-open packages. Intended for one-time use....
Used to establish and temporarily maintain suprapubic access during endoscopic procedures. Supplied sterile in peel-open packages. Intended for one-time use....
Used for pulling sutures from a vaginal incision into the suprapubic area during bladder suspension surgery. The double needle design permits simultaneous suture placement. Supplied sterile in peel-o...
Medicine Products: