Navigation Links
Anemic Patients With MDS Gain Long-Term Benefits From Erythropoietin and Myeloid Growth Factor Hormones
Date:9/17/2009

WASHINGTON, Sept. 17 /PRNewswire-USNewswire/ -- Myelodysplastic syndromes (MDS), a group of blood disorders that can lead to acute myeloid leukemia (AML) in some patients, often cause severe anemia (when the body lacks a sufficient number of functional red blood cells). While certain treatments can help manage the symptoms of anemia, some studies have suggested that they may lead to complications. A new study, however, demonstrates that MDS patients with anemia may benefit from treatment with an erythropoietin (EPO)-based regimen plus supportive care without added complications as compared with those receiving supportive care alone. The study will appear in the September 17 issue of Blood, the official journal of the American Society of Hematology.

The phase III prospective, randomized trial, conducted by research teams of the Eastern Cooperative Oncology Group, was designed to evaluate the efficacy and safety of EPO with or without myeloid growth factor treatment (G-CSF, or granulocyte colony-stimulating factor) and supportive care (SC) with red blood cell transfusions for patients with early-stage MDS (n=53), in comparison to supportive care alone (n=57).

For the study, the researchers followed MDS treatment and dosing guidelines recommended by the National Comprehensive Cancer Network, which include managing anemia with erythropoiesis-stimulating agents (ESAs) such as EPO. EPO is a drug that imitates the action of the hormone erythropoietin, which stimulates the body to produce more red blood cells. Generally, therapy with G-CSF interacts with EPO treatment synergistically to improve erythroid (red blood cell) responses, especially in MDS patients that do not respond to EPO alone.

"EPO is a recommended treatment for MDS, but the combination with G-CSF and supportive care required comparative studies in this patient population," according to lead study author Peter Green
'/>"/>

SOURCE American Society of Hematology
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novel Small Molecule Therapy Shows Benefit for Anemic Patients Via Hydration of Red Blood Cells
2. Lexicon Completes Phase 1 Clinical Trial and Initiates Phase 2 Clinical Trial of LX4211 in Patients With Type 2 Diabetes
3. Alexza Announces Preliminary Results from its AZ-104 (Staccato(R) Loxapine) Phase 2b Trial in Patients with Migraine Headache
4. Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
5. Schering-Plough Reports Long-Term Vicriviroc Data From Phase II Open-Label Extension Study in Treatment-Experienced HIV-Infected Patients
6. Two New Studies Report Increased Survival Rates in Tamiflu(R)-Treated Patients with Avian Flu (H5N1) and Severe Seasonal Flu
7. New Data Show Patients With Chronic Low Back Pain Maintained Pain Reduction on Cymbalta(R)
8. Yoga Benefits Back-Pain Patients
9. Two-Year SYNTAX Data Show Comparable Safety Outcomes for Complex Patients Treated With TAXUS(R) EXPRESS(R) Stents and Bypass Surgery
10. CRESTOR(R) Reduced Risk of Cardiovascular Events in Elderly Patients in New Analysis of Jupiter
11. New Large-Scale, Global Study Provides Additional Information About an Intensified Dose-Regimen of PLAVIX(R) in Acute Coronary Syndrome Patients Undergoing Angioplasty
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... CHAPEL HILL, N.C. , May 22, 2015 ... is critical to pharmaceutical brand recognition and success. ... Practices, LLC conducted a study to provide pharmaceutical ... level of investment (FTEs and budget) that are ... companies. Pharmaceutical and biotech marketing managers can utilize ...
(Date:5/22/2015)... , May 22, 2015 Electrophysiologist Kevin ... recently traveled to Boston, MA ... the 2015 Heart Rhythm Society conference. These scientific ... focus on the ideas, people and technology that ... is a hybrid, minimally invasive cardiac operation that ...
(Date:5/22/2015)... May 22, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX), ... repair and regeneration, today announced that J.J. Finkelstein ... present a corporate overview at two upcoming investor conferences. ... SeeThruEquity 4 th Annual Microcap Conference on Thursday ... at 11:00 am EDT.  A webcast will ...
Breaking Medicine Technology:Effective Marketing Services Group Critical for Pharmaceutical Brand Recognition 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 3RegeneRx to Present at 2 Investor Conferences 2RegeneRx to Present at 2 Investor Conferences 3
... of Minnesota is opening a new helipad on its Minneapolis ... they need it most. The new helipad ... minutes, by eliminating the need to move patients from the ... a distance of about a half a mile. ...
... 2011 Abaxis, Inc. (NasdaqGS: ABAX), a medical products ... Kenneth Aron, Chief Technology Officer, will present at the ... Investor Forum on Thursday, November 10, 2011 at 1:20 ... Grand Hyatt New York Hotel in New York City. ...
Cached Medicine Technology:Children's Hospitals and Clinics of Minnesota Opens New Helipad on its Minneapolis Campus 2Abaxis, Inc. to Present at Sidoti & Company's New York II Emerging Growth Institutional Investor Forum 2
(Date:5/22/2015)... (PRWEB) May 22, 2015 Pioneer Millworks, ... at the forefront of designing with reclaimed wood, introducing ... in Los Angeles, California. Their newest offerings, Vat 35, ... much-anticipated surface and color to America's largest design event. ... exhibit at each show, anxious to see and feel ...
(Date:5/22/2015)... River Valley Health Partners (RVHP) Board ... system’s Chief Financial Officer (CFO), will be leaving the ... the company CFO since 2011. , The Board of ... health system as CFO. Wesley will oversee the health ... Board of Trustees conducts a formal search for a ...
(Date:5/22/2015)... 2015 Omar Ahmad Barrada, a junior ... in the 2015 Congress of Future Medical Leaders in ... gathering of “America’s highest achieving high school students.” , ... set new goals and learn better study habits,” said ... during which we can ask the surgeons questions.” , ...
(Date:5/22/2015)... May 22, 2015 “It’s like ... SLP, RAC-CT, CHHRP-QT, Vice President of Clinical Operations/Education ... important ‘language’ that impacts how care is coded ... in long term care reimbursement, operations and compliance ... and talent management, launches a new series of ...
(Date:5/22/2015)... May 22, 2015 Coordinating care ... difficult process. Historically providers have not been reimbursed ... Starting in 2015, Medicare has paved the way ... Thanks to the launch of Oculus Health ... health systems using the platform will now be ...
Breaking Medicine News(10 mins):Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 3Health News:River Valley Health Partners Announces CFO Transition, Appointment of Interim CFO 2Health News:Milton Hershey School Student Chosen for Congress of Future Medical Leaders 2Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 2Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 3Health News:Oculus Health Care Coordination Platform Officially Launched 2Health News:Oculus Health Care Coordination Platform Officially Launched 3Health News:Oculus Health Care Coordination Platform Officially Launched 4
... The public health problem that needs to be addressed next ... who have come together to discuss the latest in pain ... American Academy of Pain Medicine (AAPM), February 12-16 at the ... Americans, with the help of their physicians, have been asked ...
... Feb. 16, 2008 According to the National Osteoporosis ... percent of them women. Because the disease causes a ... fractures, spinal fractures and a whole host of debilitating ... popularly prescribed Fosamax (alendronate sodium), are a class of ...
... also found IBS 2 times more likely in people with ... be a link between allergies and irritable bowel syndrome (IBS) ... Medical Center in Chicago. , IBS occurs in about 15 ... allergen exposure may lead to IBS symptoms in some patients, ...
... Creating PEPFAR; However, Proposed Changes in ... Cut Heart from Lifesaving Effort, WASHINGTON, Feb. 16 ... and highlight programs funded by the,President,s Emergency Plan for AIDS ... created at his request, AIDS Healthcare,Foundation (AHF) ( http://www.aidshealth.org ) ...
... examines how pesticides that run off the land and mix ... expected toxic effect on the salmon nervous system. These pesticides ... as mixtures in the food supply for humans may also ... pretty good handle on how to assess the health effects ...
... Calif., Feb. 15 Kaiser Permanente has,announced ... president, Membership,Administration. Cleary previously served as director, ... In his role, Cleary is responsible ... San Diego and Fort Worth, Texas. These,locations ...
Cached Medicine News:Health News:Physicians focus on stopping pain epidemic 2Health News:Physicians focus on stopping pain epidemic 3Health News:Physicians focus on stopping pain epidemic 4Health News:Physicians focus on stopping pain epidemic 5Health News:Physicians focus on stopping pain epidemic 6Health News:Link between treating osteoporosis with bisphosphonates and incidence of bone necrosis examined 2Health News:Allergy Disorders Linked With Irritable Bowel Syndrome 2Health News:Bush AIDS Legacy at Risk, Says AHF 2Health News:Greg Cleary Named Vice President, Membership Administration for Kaiser Permanente 2
16mm from Mid-Screw to Blunt Tips, Gently Curved Blades; overall length 120mm; Stainless Steel...
4 Gently Curved, Prongs, 5mm Extended, Stainless Steel Tip; with Titanium Handle....
Straight shaft; a 5mm platform with 0.3mm 1x2 teeth; In Titanium....
Gently curved 5mm Platform With 12, 0.12mm Teeth; In Titanium....
Medicine Products: