Navigation Links
AndroScience Corporation Awarded a $3.8 Million, 3-Year Milestone-Driven, Cooperative Translational Research Grant from the NIH to Develop an Oral Treatment for Spinal Bulbar Muscular Atrophy (Kennedy's Disease)
Date:1/25/2011

studies.  To date, ASC has provided robust proof of concept data using an ARD enhancer compound; demonstrating treatment ameliorates cardinal features of SBMA neuromuscular pathology, restores functional activity, and improves survival in a SBMA transgenic mouse model.

About Spinal Bulbar Muscular Atrophy (SBMA) – Kennedy's DiseaseSpinal and bulbar muscular atrophy (SBMA or Kennedy's Disease) is a rare hereditary neurodegenerative disease that affects lower motor neurons, with progressive muscle atrophy and weakness of the bulbar, facial, and limb muscles. The disease results in progressive dysphasia, motor dysfunction, and typically affects men in the fourth or fifth decade of life.  SBMA is caused by a mutation in the X-chromosome linked androgen receptor (AR) gene that results in excessive repeats of the amino acid glutamine (polyQ) within AR protein.  A molecular genetic test is clinically available which has a 100% mutation detection rate to definitively diagnose SBMA.  Neurotoxicity caused by these expanded polyQ AR aggregates is believed to play a pivotal role in the pathogenesis of SBMA.  SBMA is considered an orphan drug indication and no approved therapy exists.  Furthermore, very few drug candidates are being evaluated in clinical trials.  

About AndroScience CorporationAndroScience (ASC) is a privately held San Diego, California based pharmaceutical company applying expertise in natural product chemistry to develop proprietary small molecule drug compounds targeting disease dependent intracellular signaling events related to the Androgen Receptor (AR) and selective Signal Transducer and Activation of Transcription (STAT) pathways.  The company is focused on therapeutic indications of significant medical and commercial importance, including androgen-dependent diseases in both topical and systemic treatment settings and novel approaches to the treatment of cancer.  Active ARD enhancer
'/>"/>

SOURCE AndroScience Corp.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. AndroScience Corporation Forms Strategic Alliance With Taiwan Based Orient Europharma to Develop Novel Topical Acne Therapeutic
2. AndroScience Corporation Announces Phase 2a Study Results on ASC-J9(TM) for the Treatment of Acne
3. Genelux Corporation Expands Board of Directors, Appointing Dennis Fenton, Former Amgen Executive
4. Celsion Corporation Announces Completion of $5.1 Million Registered Direct Offering
5. CVS Caremark Corporation to Hold Fourth Quarter 2010 Conference Call
6. Medical Simulation Corporation to Feature Full Spectrum of Services and Simulation-Based Curriculum at the 11th Annual International Meeting on Simulation in Healthcare
7. Stryker Corporation Named One of FORTUNE Magazines 100 Best Companies to Work For
8. Luminex Corporation Fourth Quarter and Full Year 2010 Earnings Release Scheduled for February 7, 2011
9. Kensey Nash Corporation Announces Its Second Quarter Fiscal Year 2011 Earnings Release Date and Teleconference
10. Rochester Medical Corporation Announces Agreement to Acquire Laprolan B.V.
11. TREVENTIS Corporation Founder Wins Prestigious Discovery Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... (NYSE: MNK ) announced today that its ... The open-ended authorization permits the company to repurchase up ... "Funding additional initiatives and seeking attractive business ... pursue a range of focused growth strategies," said ...
(Date:1/22/2015)... , Jan. 22, 2015  ViewRay™, a privately held ... into an exclusive distributor agreement with ITOCHU Corporation (Tokyo ... therapy system for the treatment of cancer in ... system, is the world,s first and only MRI-guided radiation ...
(Date:1/22/2015)... , Jan. 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; ... a focus on Omega-3 therapies for cardiovascular disease and overall ... the Company,s accomplishments in 2014 and its outlook for 2015 ... Dear Fellow Shareholders, We would like to take ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7
... U.S. Food and Drug Administration has scheduled its fourth ... those unfamiliar with the process for Feb. 28 – ... Keck Graduate Institute. (Logo:   http://photos.prnewswire.com/prnh/20090824/FDALOGO ) ... Organization of Rare Disorders and the Genetic Alliance, will ...
... /PRNewswire-Asia/ -- China Sky One Medical, Inc. ("China ... CSKI ), a leading fully integrated pharmaceutical ... today announced that Heilongjiang Tianlong Pharmaceutical, Inc. ("Tianlong"), ... a "Top Ten Branded Company Trusted by Consumers" ...
Cached Medicine Technology:Fourth FDA Orphan Drug Designation Workshop Scheduled for Feb. 28 - March 1, 2011 2China Sky One Medical Receives Medical Industry Awards 2China Sky One Medical Receives Medical Industry Awards 3
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue Cross) wants ... “Live Fearless.” , The “Faces of Fearless” campaign ... how they or someone they know has faced a challenge, ... moment. By telling these types of stories through livefearlessmn.com, participants ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 ... after Fresenius Medical Care recalled its GranuFlo and NaturaLyte ... multidistrict litigation underway in U.S. District Court, District of ... dated January 20th, the Court has remanded a case ...
(Date:1/22/2015)... New York, NY (PRWEB) January 22, 2015 ... American College of Sports Medicine flagship journal Medicine ... supplementation with L-Citrulline before exercise may help reduce ... strenuous exercise. 1 , Participants in the ...
(Date:1/22/2015)... WASHINGTON, DC (PRWEB) January 22, 2015 ... conditions in vulnerable communities and cause financial distress to ... report by analysts at Howard University’s Center on Race ... of dollars in economic activity, payday loans at the ...
(Date:1/22/2015)... released a new blog post explaining the importance of keeping a ... of an auto insurance policy . , Clients who driver ... their vehicle insurance policies. The safety a vehicle offers from its ... of this, drivers should always carry a first aid kit in ...
Breaking Medicine News(10 mins):Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2
... Discussions Also to Feature Top Experts on the Battle Against H1N1 ... reform headed to the floor of the House and Senate, the ... discussions designed to shed light on what the looming changes will ... the Top of the Hill Banquet and Conference Center, at the ...
... Company allegedly failed to correct violations , ... of Justice, on behalf of the U.S. Food and ... against Rel,s Foods Inc. (Rel,s), of Oakland, Calif., seeking ... adulterated food products. , (Logo: ...
... Rawat Foundation,s grant to St. John of Jerusalem Eye Hospital will ... 8 A $25,000 grant by The Prem Rawat Foundation (TPRF) ... eye care for 30,000 children in an area of the world ... 50% of the people in the Palestinian Territories, one of the ...
... infection with high-risk types of human papillomavirus (HPV), a ... of cervical cancer. Current guidelines prioritize HPV vaccination of ... in previous studies, but the value of vaccinating boys ... new study, Harvard School of Public Health (HSPH) researchers ...
... Palliative Care Psychiatry Program only one of its kind ... The Palliative Care Psychiatry Program at San ... named the winner of the 2009 Gold Achievement Award by ... Irwin, MD, PhD is Director of the Palliative Care Psychiatry ...
... Reportlinker.com announces that a new market ... , Reportlinker Adds The Market ... Pharmaceutical, Diagnostic and Device Product Markets ... , At their most basic level, wellness ...
Cached Medicine News:Health News:Tom Daschle, Richard Gephardt and Other Health Care Leaders to Diagnose Health Care Reform Battle in the Final Days of the Debate 2Health News:Tom Daschle, Richard Gephardt and Other Health Care Leaders to Diagnose Health Care Reform Battle in the Final Days of the Debate 3Health News:FDA Takes Enforcement Action Against Ready-to-Eat Sandwich Manufacturer 2Health News:TPRF Gives US$25,000 to Help Provide Eye Care for Children in Palestinian Territories 2Health News:Vaccinating boys against human papillomavirus not cost-effective 2Health News:Vaccinating boys against human papillomavirus not cost-effective 3Health News:San Diego Hospice and The Institute for Palliative Medicine Program Wins National American Psychiatric Association Gold Achievement Award 2Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 2Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 3Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 4Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 5Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 6Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 7Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 8Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 9Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 10Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 11Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 12Health News:Reportlinker Adds The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets 13
Unipolar Atrial "J" Lead...
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
Medicine Products: