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Anastrozole Confirmed Superior in Breast Cancer Prevention
Date:12/14/2007

ngly, the incidence of a new cancer occurring in the other breast was significantly lower at 10 years in women who took anastrozole compared with those who received tamoxifen. Tamoxifen has been approved for several years for use in preventing new breast cancers, and it now appears that anastrozole may be even more effective.

Many patients have been reluctant to begin treatment with anastrozole because of concern about the potential for increased bone loss and risk of fracture that can occur with the use of aromatase inhibitors. It was not known whether these effects would persist after the end of treatment. With the new data presented today, it appears that they do not. Although the incidence of fractures was nearly 30% higher in patients treated with anastrozole while they were taking the drug, that difference disappeared after treatment was completed. In addition, there do not appear to be any other important side effects related to anastrozole treatment at this time.


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SOURCE San Antonio Breast Cancer Symposium
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