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Anadys Retains Lazard as Strategic Advisor
Date:5/26/2010

SAN DIEGO, May 26 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) today announced that it has retained Lazard Freres & Co. LLC as its strategic advisor as it pursues various avenues aimed at value recognition for its stockholders from its non-nucleoside polymerase inhibitor, ANA598, in development for the treatment of hepatitis C.  Anadys recently released positive safety and antiviral response data at the conclusion of 12 weeks of dosing ANA598 in combination with pegylated interferon and ribavirin (current standard of care, or SOC) in an ongoing Phase II study.

"The impressive safety and antiviral response data we recently released establish a very attractive profile for ANA598," said Steve Worland, Ph.D., President and CEO of Anadys.  "We look forward to working with Lazard as we pursue options to maximize recognition of the value inherent in the ANA598 program."

Recently Released ANA598 Data

Anadys recently reported that patients treated with ANA598 at 400 mg bid demonstrated excellent safety through 12 weeks and that 75% of patients at this dose level achieved undetectable levels of virus (<15 /IU/mL) at week 12, known as complete Early Virological Response or cEVR.  These data confirmed the positive profile previously reported for ANA598 at 200 mg bid through 12 weeks.  Based on comparable antiviral potency and excellent safety at both doses, Anadys has identified 200 mg bid as the optimal dose to advance in combination with current SOC in future clinical trials.  Anadys believes that lower doses and once daily dosing also merit exploration, especially in combin
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SOURCE Anadys Pharmaceuticals, Inc.
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