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Anadys Pharmaceuticals Initiates Phase I Clinical Trial of ANA598
Date:6/2/2008

nations of two or more direct antivirals. It is expected that the next generation of therapies for treatment of HCV will include small molecules, such as ANA598, that act directly upon specific viral enzymes to inhibit viral replication. These direct antivirals are expected to improve overall therapy by increasing cure rates and improving tolerability and convenience of treatment.

About Anadys

Anadys Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company dedicated to improving patient care by developing novel medicines in the areas of hepatitis C and oncology. The Company is developing ANA598, a non-nucleoside polymerase inhibitor for the treatment of chronic hepatitis C and ANA773, an oral TLR7 agonist prodrug for the treatment of cancer.

Safe Harbor Statement

Statements in this press release that are not strictly historical in nature constitute "forward-looking statements." Such statements include, but are not limited to, references to (i) the planned trial design of the ANA598 healthy volunteer study; (ii) Anadys' expectation to begin a Phase Ib study of ANA598 in the third quarter of 2008; (iii) Anadys' belief that ANA598 has the potential to become an important component of future combination therapy for patients with HCV infection and that the full benefit of direct antivirals will be demonstrated when studied as components of novel combination regimens incorporating multiple anti-HCV agents; (iv) Anadys' ability to achieve important clinical milestones in the ANA598 and ANA773 programs; and (v) expectations regarding the evolution of the market for HCV therapies. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause Anadys' actual results to be materially different from historical results or from any results expressed or implied by such forward-looking statements. For example, the results of preclinical studies may not be predictive of future results, and Anad
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SOURCE Anadys Pharmaceuticals, Inc.
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