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Anadys Announces Issuance of U.S. Patent Covering Setrobuvir (ANA598)
Date:6/1/2011

SAN DIEGO, June 1, 2011 /PRNewswire/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) today announced issuance of the U.S. patent covering setrobuvir (ANA598), the Company's Direct-Acting Antiviral (DAA) in Phase IIb development for chronic hepatitis C virus infection (HCV).  U.S. Patent No. 7,939,524, granted to Anadys by the United States Patent and Trademark Office, recognizes the Company's intellectual property rights to the composition of matter and methods of use for setrobuvir (ANA598) and related compounds.  

"Securing U.S. patent protection is a critical step that significantly enhances the value of setrobuvir," said Steve Worland, Ph.D., President and CEO of Anadys.  "This milestone comes at an important juncture in the setrobuvir development program, as we complete enrollment of our Phase IIb trial and begin the investigation of setrobuvir in combination with other DAAs."

About Setrobuvir (ANA598)

Setrobuvir (ANA598), the Company's wholly-owned DAA, is currently in Phase IIb testing in combination with pegylated interferon and ribavirin for the treatment of HCV.  Anadys recently announced a cross-company clinical trial agreement with a large, commercial-stage biopharmaceutical company to study setrobuvir (ANA598) in combination with another DAA in healthy volunteers.  Setrobuvir is the name recently adopted for ANA598 by the United States Adopted Names (USAN) Council.

Setrobuvir (ANA598) is an HCV RNA polymerase inhibitor that belongs to a chemical class referred to as non-nucleosides.  Setrobuvir has a well-characterized safety database in which more than 150 subjects have received the agent to date.  Setrobuvir (ANA598) has received Fast Track Status from the FDA for the treatment of chronic hepatitis C.

About the Phase IIb Study of Setrobuvir (ANA598)

In the ongoing Phase IIb study
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SOURCE Anadys Pharmaceuticals, Inc.
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