Navigation Links
Amylin and Takeda Discontinue Development of Pramlintide/Metreleptin Combination Treatment for Obesity Following Commercial Reassessment of the Program
Date:8/4/2011

SAN DIEGO, Aug. 4, 2011 /PRNewswire/ -- OSAKA, Japan, Aug. 5, 2011 -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that they are discontinuing development of pramlintide/metreleptin, an investigational combination therapy for the treatment of obesity that comprises pramlintide, an analog of the natural hormone amylin, and metreleptin, an analog of the natural hormone leptin. The joint decision was based on a commercial reassessment of the pramlintide/metreleptin program, which had been in Phase 2 development as a twice-a-day injection formulation. The commercial assessment took into account a revised development plan as well as evolving dynamics within the obesity therapeutic area. The companies will continue to evaluate other assets as potential candidates for the treatment of obesity and related indications under the terms of their existing collaboration agreement.

"The interplay of hormonal signals, such as amylin and leptin, plays a crucial role in the regulation of body weight," said Christian Weyer, M.D., Senior Vice President, Research and Development at Amylin Pharmaceuticals. "Advances in peptide engineering and delivery may help us leverage this biology to develop a therapy with less frequent dosing. With our partner, Takeda, we look forward to continuing to explore new options for the obesity market."

"As the prevalence of obesity continues to rise in the U.S., it is important to develop innovative weight loss therapies for patients with this condition," said David Recker, M.D., Senior Vice President, Clinical Science, Takeda Global Research & Development Center, Inc.

While the pramlintide/metreleptin development program has been discontinued, Amylin and Takeda will continue to investigate the previously announced antibody-related laboratory finding with metreleptin treatment i
'/>"/>

SOURCE Amylin Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Amylin Pharmaceuticals to Webcast Second Quarter Results
2. U.S. District Court Rules in Favor of Lilly in Amylin Litigation
3. Amylin Pharmaceuticals Issues Statement Regarding U.S. District Court Order
4. Amylin Pharmaceuticals Obtains Temporary Restraining Order Against Eli Lilly
5. Lilly Comments on Court Ruling in Amylin Litigation
6. Amylin Pharmaceuticals to Present at Annual Meeting of Stockholders
7. Lilly Provides Its Perspective in Response to Amylin Lawsuit
8. Lilly Provides Statement in Response to Amylin Lawsuit
9. Amylin Pharmaceuticals Files Suit Against Eli Lilly
10. JDRF and Amylin Partner to Investigate Co-Formulating Two Hormones for Treatment of Type 1 Diabetes
11. Amylin Pharmaceuticals to Present at the Bank of America 2011 Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... July 28, 2015 The Canadian ... the Canadian Anti-Fraud Centre (CAFC), continues ... using the CIPA verification seal on illegitimate pharmacy ... legitimate online pharmacy member companies who have maintained ... to more than 10 million Americans since 2002. ...
(Date:7/28/2015)... 28, 2015  Today, Sekisui Diagnostics announces the launch ... efficient instrument, with a broad menu of high quality ... the physicians, office or hospital laboratory. ... tests/hour with ISE, 72 patient sample on-board capability, minimizes ... assays (+3 ISE) to meet the testing needs of ...
(Date:7/28/2015)... the first virtual care solution to empower health care systems ... virtual care service line, announced an agreement with Group ... in use. ... As health systems consider how to ... providing their own branded online care for common medical conditions. ...
Breaking Medicine Technology:Canadian International Pharmacy Association (CIPA) Continues to Fight Rogues Fraudulently Using the Trusted CIPA Verification Seal 2Canadian International Pharmacy Association (CIPA) Continues to Fight Rogues Fraudulently Using the Trusted CIPA Verification Seal 3Sekisui Diagnostics Announces Launch of SK500 Clinical Chemistry System for US Laboratories 2Zipnosis Announces Group Health to use Virtual Care Service Line 2Zipnosis Announces Group Health to use Virtual Care Service Line 3
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... People that ... from two new products on Mercola.com: a vertical “garden tower” and enhanced mineral product ... be squeezed into small corners on a porch, balcony, or rooftop – can hold ...
(Date:7/29/2015)... ... ... Hernia repairs have always been common and routine surgical procedures and technologies ... Center for Health Statistics indicates that more than five million Americans currently suffer from ... only effective treatment for a hernia is surgery, only about 750,000 Americans will actually ...
(Date:7/28/2015)... VA (PRWEB) , ... July 29, 2015 , ... Talking ... Aug. 18, 2015 — 1:30 p.m. – 3:00 p.m. EDT, http://www.fdanews.com/productpipeline , ... they can — and can’t — say about it is tightly regulated by the ...
(Date:7/28/2015)... ... July 28, 2015 , ... Jordan ... the Get With The Guidelines®-Stroke Gold Plus Award for implementing specific quality improvement ... outcomes. , The Get With The Guidelines-Stroke program recognizes hospitals that demonstrate ...
(Date:7/28/2015)... (PRWEB) , ... July 28, 2015 , ... ... patented products, announces Skimmer Helper, a household invention that cleans pools efficiently - ... $3 billion," says Scott Cooper, CEO and Creative Director of World Patent Marketing. ...
Breaking Medicine News(10 mins):Health News:Mercola.com Introduces NEW Garden Tower and Enhanced Mineral Solution for Healthy Plants 2Health News:National Statistics Reflect NCMA General Surgery Physicians Findings: Hernia Patients Who Seek Treatment Promptly are More Likely to Enjoy a Quick Recovery 2Health News:National Statistics Reflect NCMA General Surgery Physicians Findings: Hernia Patients Who Seek Treatment Promptly are More Likely to Enjoy a Quick Recovery 3Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 2Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 3Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 4Health News:Jordan Valley Medical Center and Jordan Valley Medical Center West Valley Campus Receive Stroke Award 2Health News:Jordan Valley Medical Center and Jordan Valley Medical Center West Valley Campus Receive Stroke Award 3Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 2Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 3Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 4Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 5
... Deficiency Notice Relating to Market Value , ... QC, Dec. 5 /PRNewswire-FirstCall/ - BELLUS Health Inc. (NASDAQ: ... light of continuing significant fluctuations in world capital markets, ... NASDAQ Capital Market, while continuing to maintain a full ...
... Boutique firm specializing in catastrophic injuries caused by medical negligence moves into ... ... December 5, 2008 -- The Law Offices of Christian A. Lodowski ... relocated to new office space in Towson., , ,The firm has moved ...
... "Company") (Nasdaq and MTA: CTIC) today announced that that its Board,of ... portion or all of five series of Convertible Notes (the "Notes") ... Senior Subordinated Notes due 2010, -- 5.75% Convertible ... Notes due 2010, -- 7.5% Convertible Senior Notes ...
... Without Harm and the World Health Organization today launched a global ... alternatives. , , The announcement came ... Mercury in Health Care, an event sponsored by the two organizations ... "This initiative aims to replace no less than 70 ...
... STINSON Brand Innovation, Inc.,announced that the brand consultancy has been awarded ... technology clients. , The honors include ... to logo design. , , Specifically, the ... eBioscience Logo Design (Gold), -- CSL Behring, Vivaglobin(R) ...
... your smile goes farther than you think , , THURSDAY, Dec. ... -- and so can happy friends of your friends. , ... you and people you,ve never met can have an impact ... beyond people we,re directly connected to," said study co-author James ...
Cached Medicine News:Health News:BELLUS Health is Preparing to Voluntarily Delist from the NASDAQ Capital Market 2Health News:BELLUS Health is Preparing to Voluntarily Delist from the NASDAQ Capital Market 3Health News:Law Offices of Christian Lodowski, Medical Malpractice Attorney, Relocates to New Office Park in Towson 2Health News:Cell Therapeutics, Inc. to Offer to Repurchase up to $124 Million of Its Notes 2Health News:Cell Therapeutics, Inc. to Offer to Repurchase up to $124 Million of Its Notes 3Health News:Health Care Without Harm, WHO Announce Partnership for Global Reduction of Mercury-Based Medical Devices 2Health News:STINSON Brand Innovation, Inc. Recognized With 8 Creative Awards 2Health News:Being Happy Affects Even Those You Don't Know 2Health News:Being Happy Affects Even Those You Don't Know 3
... for the High Speed Performance of ... for Additional Requirements and Information. VISUPAC ... with ophthalmologists. Important for routine operation ... short operating sequences. Extensive default settings ...
... Microscope with excellent maneuverability. Konan ... weight maintaining high quality. Easy ... by simply changing the adapter. ... has resulted in a sharp ...
... temporary implant for use with patients who ... dilator type 5S is a semicircular elastic ... pupil during phacoemulsification. It is supplied in ... Expansion of the pupil during phacoemulsification for ...
To maintain the conjunctival cul-de-sacs after enucleation or evisceration without hindering lid closure....
Medicine Products: