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Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004
Date:1/23/2010

15='82436582';s.tl(this,'o','ExternalLink');" target='_blank' href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60442-6/abstract">http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60442-6/abstract), summarized here: (http://www.nationalmssociety.org/research/research-news/news-detail/index.aspx?nid=951). Results from a later, second phase III study involving 240 people with MS (http://www.nationalmssociety.org/research/research-news/news-detail/index.aspx?nid=237), announced in 2008, confirmed the benefits seen in the first, finding that a significantly greater proportion of people on the therapy had a consistent improvement in walking speed compared to those who took placebo. Among those taking Ampyra who improved in walking speed, there was a statistically significant improvement in leg strength.

Q. What are the potential side effects of Ampyra?

A. In the first phase III study, common adverse events (side effects) experienced more often by those on active treatment included back pain, dizziness, insomnia, fatigue, nausea and balance disorder. Two serious adverse events led participants to discontinue taking the drug (one case of anxiety and one seizure in a person who developed sepsis from a urinary tract infection). In the second phase III study, additional common adverse events in those on therapy included urinary tract infection, falls, and hea
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SOURCE National Multiple Sclerosis Society
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