Navigation Links
Amikacin Inhale Shows Promising Results in Phase II Study
Date:5/19/2008

- Bayer together with Nektar Therapeutics present preliminary Phase II data

for the adjunctive treatment of pneumonia in intubated and

mechanically-ventilated patients

TORONTO and BERLIN, May 19 /PRNewswire-FirstCall/ -- Bayer HealthCare together with Nektar Therapeutics (Nasdaq: NKTR), today presented positive preliminary Phase II data on their unique drug-device combination Amikacin Inhale at the American Thoracic Society (ATS) annual meeting. Amikacin Inhale, currently being studied for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients, achieved over 1000 times greater lung exposure to the antibiotic amikacin as compared to intravenous route of administration. This shows that targeting antibiotic therapy to the site of infection might offer superior bacterial eradication and increased efficacy, which may result in a higher likelihood of the patient's survival. Currently, Gram-negative pneumonia carries a mortality risk as high as 50 percent in mechanically-ventilated patients(1).

"Mechanically-ventilated patients in critical care units are at particularly high risk of developing pneumonia. Most of them are already seriously ill because of severe underlying diseases," said Professor Michael Niederman, Chairman, Department of Medicine, Winthrop University Hospital, New York, and one of the lead investigators of the study. "Because of the high morbidity and mortality of Gram-negative pneumonia, fast and efficient treatment is essential. Intravenous therapies cannot always reach effective concentrations in infected lungs at tolerable doses. The new study data shows that the device successfully delivers the antibiotic directly to the site of inf
'/>"/>

SOURCE Nektar Therapeutics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
2. Inhaled Steriods Used as Preventive Treatment Post 9/11
3. Arriva Pharmaceuticals Moves Forward to Phase 2b Development of Lead Inhaled Protein rAAT Replacement Therapy for Hereditary Emphysema
4. Nektar Terminates All Negotiations With Potential Partners for Inhaled Insulin; Increased Number of Lung Cancer Cases Observed in Ongoing Clinical Studies of Inhaled Insulin Patients
5. Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers Diarrhea Patch Vaccine
6. Study Shows Combination Therapy Incorporating AVODART(R) and Tamsulosin Provides Continuous Symptom Improvement Over 2 Years
7. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
8. Kosans Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial
9. Study Shows Plasma-Derived Human Thrombin Equivalent to Bovine Thrombin in Achieving Hemostasis in Surgery
10. Cleveland Clinic Study Shows the Diabetes Drug Pioglitazone Reduces Risk of Death, Heart Attack and Stroke, but Increases Risk of Heart Failure
11. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2015)... 2015 RnRMarketResearch.com adds Corneal ... report to its store. This report p provides ... The report "Corneal Ulcers - Pipeline Review, H2 ... for Corneal Ulcers. Corneal Ulcers are primarily result ... viral infections & fungal infections. The symptoms of ...
(Date:2/26/2015)... 2015  Today the National Safety Council ... physical side effects of pain medications , ... Vicodin and Oxycontin, are safer options than over-the-counter pain ... painkillers than on heroin and cocaine combined," said ... "Yet, these medications are marketed as the Cadillac option ...
(Date:2/26/2015)...  Mail-service and specialty pharmacies will save ... health plans $23.3 billion over the next decade, ... Management Association (PCMA). "Home delivery of ... easiest ways to reduce health costs," said PCMA ... should resist efforts to restrict these cost-saving tools." ...
Breaking Medicine Technology:Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 2Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 3Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 4Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 5National Safety Council: Opioid prescription painkillers have hidden, deadly side effects 2PCMA: Report Shows High-Tech Specialty and Mail-Service Pharmacies Will Reduce Costs for Texas Employers, Consumers and Public Programs by $23.3 Billion 2
... growing appetite for health and wellness devices, and this represents ... been tapped, according to a study from IBM (NYSE: ... wellness device innovations of the future, which have the potential ... healthcare provider over the next five years. (Photo: ...
... 2011 Providers of durable medical equipment and services (DME) ... repeal Medicare,s controversial "competitive" bidding for homecare, which cuts quality ... The program is opposed by the ... advocacy groups such as the ALS Association and ...
Cached Medicine Technology:IBM Study Identifies New Generation of Connected Health Devices 2IBM Study Identifies New Generation of Connected Health Devices 3IBM Study Identifies New Generation of Connected Health Devices 4IBM Study Identifies New Generation of Connected Health Devices 5At-Home Care Businesses Urge President Obama to Repeal Medicare Program that Cuts Access to Homecare 2At-Home Care Businesses Urge President Obama to Repeal Medicare Program that Cuts Access to Homecare 3At-Home Care Businesses Urge President Obama to Repeal Medicare Program that Cuts Access to Homecare 4
(Date:2/28/2015)... Vancouver personal injury lawyers at Jiwa Law Corporation recently announced ... They stated that in many cases, missing an important time ... Many a time, delays in making an injury claim can ... As a result, experts at Jiwa Law Corporation suggest that ... injury lawyer in order to know more about their rights. ...
(Date:2/28/2015)... Pioneer Millworks reclaimed USA wood will be on ... Show, an annual, premier sustainable building event in Tokyo, ... manufacturers of the latest building products, services and technology. ... manufactured by Pioneer Millworks from their Oregon and New ... hotels, retailers, and corporate offices. Nichibi Global , ...
(Date:2/28/2015)... Kaylie Corrigan, Outdoor Supervisor at ... and current student obtaining her Masters degree in social ... forum in psychoeducation on substance use for teens at ... part of her studies. , “Even though these students ... counseling at the high school and junior high school ...
(Date:2/28/2015)... Developers of FCPX plugins and ... plugin for Final Cut Pro X entitled FCPX Overlay Chromatic ... gives users total control over 6k lens dirt overlays inside ... Film Studios. “FCPX Overlay Chromatic was professionally designed to add ... , FCPX Overlay Chromatic Grunge 6K is a resourceful tool ...
(Date:2/28/2015)... The World Scout League Commission (WSLC), ... potential EMTs and firefighters, recently announced its decision to ... to raise charitable donations for age-related research. The five-kilometer ... be held on March 29, 2015; registration will start ... 3:30 p.m. , To participate in the race, ...
Breaking Medicine News(10 mins):Health News:Jiwa Law Corporation Recently Announced That Time Delays May Weaken Personal Injury Claims 2Health News:US Reclaimed Wood from Pioneer Millworks to be Featured at Architecture & Construction Materials Show in Tokyo. 2Health News:Staff at Arizona Drug Addiction Treatment Center Starts Teen Sobriety Support Group at Local High School 2Health News:Pixel Film Studios released a new overlay plugin entitled FCPX Overlay Chromatic Grunge 6K exclusively for Final Cut Pro X users 2Health News:Bitcoin Run Is The World Scout League Commission’s Newest Project for Charity 2
... HealthDay Reporter , TUESDAY, Feb. 28 (HealthDay News) ... your diet can boost your immune function and lower your ... good thing. Higher-than-normal levels of selenium may contribute to the ... a new review of evidence finds. "There is ...
... diabetes could be adapted into a home DNA detector that ... in human body fluids, in food and in other substances, ... this adaptation of the ubiquitous personal glucose monitor, typically used ... Analytical Chemistry . Yi Lu and Yu Xiang point ...
... in French . Marie Renaud, an ... Health, will be joining the World Health Organization,s African office, ... fight against Noma. This disease, scientifically called cancrum oris, eats ... the existence of a cheap and easy treatment, it remains ...
... , TUESDAY, Feb. 28 (HealthDay News) -- Even ... may still have a hard time using the information to ... the scientists examined the calorie listings for 200 food ... New York City neighborhood of Harlem. Too often, calorie ...
... , TUESDAY, Feb. 28 (HealthDay News) -- Teenagers who ... children to its aftereffects, Canadian researchers report. Concussions ... for reading and calculating, and those effects can last ... "Contrary to the belief by some parents and ...
... TUESDAY, Feb. 28 (HealthDay News) -- Menstrual cramps are the bane ... vitamin D may one day be added to the meager list ... study in Italy found that a single, high dose of cholecalciferol ... marked reduction in menstrual cramps, with the largest benefits observed in ...
Cached Medicine News:Health News:Selenium Supplements May Help -- or Harm 2Health News:Selenium Supplements May Help -- or Harm 3Health News:Montrealer heads to Congo to fight childhood disfigurement 2Health News:Many Gaps in Fast-Food Nutrition Information 2Health News:Teens May Fare Worse After Concussion Than Children or Adults 2Health News:Teens May Fare Worse After Concussion Than Children or Adults 3Health News:Vitamin D3 Might Ease Menstrual Cramps 2Health News:Vitamin D3 Might Ease Menstrual Cramps 3
Four way compression with simple contact closure...
Facial Chin and Neck Support...
Abdominal Compression for Men and Women...
Male high waisted compression girdle with CDIs Wonderfabric™...
Medicine Products: