Navigation Links
Amicus Therapeutics Announces Positive Progress of Three Lead Clinical Programs and General Outlook for 2009
Date:1/12/2009

se

A Phase 2 clinical trial of Plicera in Gaucher patients is ongoing. This 6 month study is designed to evaluate safety as well as to demonstrate trends of efficacy as measured by the standard endpoints in Gaucher disease. Target enrollment of 16 patients for this study is expected to be surpassed and the results are expected to be available in the third quarter of 2009.

In addition, Amicus is working closely with its partner Shire HGT to prepare for Phase 3 development of Plicera pending the results of the ongoing Phase 2 trial.

AT2220 (1-deoxynojirimycin HCl) for the treatment of Pompe Disease

A Phase 2 clinical trial of AT2220 in adult Pompe patients is ongoing. The trial includes an 11 week treatment period with an optional extension study. The objectives of the trial include the evaluation of the safety and pharmacodynamics of multiple doses and regimens of AT2220. The results of this study are expected to be available in the second half of 2009.

In addition, Amicus is continuing to conduct preclinical animal studies to evaluate the effects of administering AT2220 in combination with ERT. Encouraging preliminary results were announced at the American Society of Human Genetics conference in November 2008. These results indicated that AT2220 in combination with ERT significantly increases the stability and tissue uptake of ERT. Amicus is conducting additional preclinical proof-of-concept studies to determine the feasibility of a combination that may be appropriate for Pompe patients who are not amenable to chaperone monotherapy. Amicus expects to announce additional results in the first quarter of 2009.

2009 FINANCIAL GUIDANCE

Amicus expects to spend a total of approximately $70 million on 2009 cash operating expenses, to be offset by $50 million in program cost-sharing reimbursements and clinical milestone payments from Shire. Amicus
'/>"/>

SOURCE Amicus Therapeutics
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Amicus Therapeutics Announces Second Quarter 2008 Financial Results
2. Amicus Therapeutics Announces Successful Completion of End of Phase 2 Meeting With FDA for Amigal in Fabry Disease
3. Amicus Therapeutics Begins Phase 2 Clinical Trial of AT2220 in Pompe Disease
4. Amicus Therapeutics Presents Data from Clinical Ex Vivo Response Study and Phase 1 Studies of AT2220
5. Amicus Therapeutics to Present at the 26th Annual JPMorgan Healthcare Conference
6. Amicus Therapeutics Announces Positive Results From Two Phase 1 Clinical Studies of AT2220 for Pompe Disease
7. Amicus Therapeutics Announces Plans to Present Phase 1 Data for AT2220 for Pompe Disease
8. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
9. Cara Therapeutics Initiates Phase II Proof-Of-Concept Trial of Novel Analgesic in Acute Post-Operative Pain
10. ExonHit Therapeutics Expands Strategic Collaboration With Allergan
11. Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Research and Markets  has announced the addition of ... to their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... needle commonly used with a syringe to inject substances ... it. A hypodermic needle is used for rapid delivery ... ingested. Hypodermic needles are broadly classified into non-safety and ...
(Date:7/11/2014)... July 11, 2014 According to ... "Endoscopy Devices Market (Endoscopes, Endoscopic Operative Devices, and Visualization ... and Forecast, 2013-2019" the global endoscopy devices market was ... expected to grow at a CAGR of 6.8% from ... USD 36.9 billion in 2019. Browse the ...
(Date:7/11/2014)... DIEGO , July 11, 2014 Neurelis, ... Corp. ("Biotie") to end the option held by Biotie ... commence further development of NRL-1 (intranasal diazepam) for pediatric ... Over the past year, Biotie has advanced ... in preparation for the pivotal clinical work required for ...
Breaking Medicine Technology:Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3
... Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) ... September 30, 2011. "We are focused on ... complete response letter around year-end and filing the lorcaserin ... the first half of next year," stated Jack Lief, ...
... China Kanghui Holdings (NYSE: KH ) ("Kanghui" or ... orthopedic implants in China, today announced financial results for the ... Highlights Total net revenue for the third ... from RMB63.6 million in the corresponding period of ...
Cached Medicine Technology:Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 2Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 3Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 4Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 5Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 6Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 7Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 8China Kanghui Holdings Reports Third Quarter 2011 Financial Results 2China Kanghui Holdings Reports Third Quarter 2011 Financial Results 3China Kanghui Holdings Reports Third Quarter 2011 Financial Results 4China Kanghui Holdings Reports Third Quarter 2011 Financial Results 5China Kanghui Holdings Reports Third Quarter 2011 Financial Results 6China Kanghui Holdings Reports Third Quarter 2011 Financial Results 7China Kanghui Holdings Reports Third Quarter 2011 Financial Results 8China Kanghui Holdings Reports Third Quarter 2011 Financial Results 9China Kanghui Holdings Reports Third Quarter 2011 Financial Results 10China Kanghui Holdings Reports Third Quarter 2011 Financial Results 11China Kanghui Holdings Reports Third Quarter 2011 Financial Results 12China Kanghui Holdings Reports Third Quarter 2011 Financial Results 13China Kanghui Holdings Reports Third Quarter 2011 Financial Results 14
(Date:7/13/2014)... treatment and variations in the quality of care are ... patients still varies widely between regions within Europe, according ... adults to date, published in The Lancet Oncology ... for most cancers of the blood has increased over ... of new targeted drugs in the early 2000s such ...
(Date:7/13/2014)... type-1 diabetes could improve patient care worldwide and ... the device,s inventors at the Stanford University School ... be published online July 13 in Nature ... type-1 diabetes outside hospital settings. The handheld microchips ... mellitus, which are both characterized by high blood-sugar ...
(Date:7/13/2014)... irrigation systems are mainly utilized for agriculture in order ... maintain soil quality. The application of micro irrigation systems ... generator for manufacturers in future. The trend of utilizing ... to the adoption of micro irrigation techniques for agriculture, ... for micro irrigation systems, as they reduce the overall ...
(Date:7/13/2014)... MarketsandMarkets recently conducted a study on the ... rendering; Layout and Animation; Image Reconstruction]: Global Advancements, ... analyzes and studies the major market drivers, restraints, ... Europe, Middle East and Africa, Asia-Pacific and Latin ... of the 3D imaging market, providing an in-depth ...
(Date:7/13/2014)... The federal court overseeing thousands of ... against Johnson & Johnson’s Ethicon, Inc. is preparing to ... to get underway next month. According to an Amended ... Southern District of West Virginia on July 9, 2014, ... 2014 at 3:00 p.m. July selection is slated to ...
Breaking Medicine News(10 mins):Health News:The Lancet Oncology: Differences in treatment likely to be behind differing survival rates for blood cancers between regions within Europe 2Health News:The Lancet Oncology: Differences in treatment likely to be behind differing survival rates for blood cancers between regions within Europe 3Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 2Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 3Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 4Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 2Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 3Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 2Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 3Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 4Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 2Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 3Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 4
... an approved clot-busting drug remains the most beneficial proven ... ,The Guidelines for the Early Management ... options – such as intra-arterial administration of clot-busting drugs ... ,The guidelines focus on the crucial ...
... may hold the key to not only stopping heart ... ever occurring//. Researchers at Mount Sinai School of Medicine ... with a novel contrast agent know as N1177 can ... stroke. The findings may help physicians diagnosis a heart ...
... resistance after the failure of an anti-HIV drug combination is ... cell losses, according to a study of patients failing treatment ... the study also found that on average, patients who remained ... choice still available to them for every six months on ...
... special envoy for the fight against tuberculosis, on Tuesday called ... the spread of TB and HIV in Africa.// ... that the two diseases are spreading rapidly across the continent ... assistance. "We are providing antiretrovirals to as many people as ...
... has evolved to become resistant to all classes of antibiotics ... U.S. Centers for Disease Control and Prevention (CDC) has said ... due to the emergence of drug-resistant strains in ... remains as there is no indication so far that the ...
... - artificial legs made in Rajasthan - is all set to ... ,Experts from the Bhagwan Mahaveer Viklang Sahayta Samiti (BMVSS) ... Indian contingent of the UN peacekeeping force in Lebanon, BMVSS general ... a camp in Lebanon April 14 to 25. Five technicians would ...
Cached Medicine News:Health News:Intravenous Delivery of Clot-busting Drug Still Best Intervention for Ischemic Stroke 2Health News:CT Imaging With Novel Contrast Agent May Predict Heart Attack in Waiting 2Health News:Is There Any Clinical Benefit to Staying on a Failing Regimen? 2Health News:Is There Any Clinical Benefit to Staying on a Failing Regimen? 3Health News:Jaipur Foot Takes Off for Lebanon 2
18 gauge straight. Fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....
Set consist of two 27 gauge, stainless steel probes with blunt tips. Probes are 11.5 cm (4.5 inches) long with 30.5 cm (12 inches) of flexible tubing (O.D. - 0.60 mm, I.D. - 0.30 mm) attached onto th...
Straight, soft flexible tip allows atraumatic entry through a retinal tear or hole for aspiration of subretinal fluids. 20 gauge x 25 mm cannula attached to 25 gauge x 6 mm tip with 13 mm flexible tu...
20 gauge x 8 mm with 15 cm high pressure extension tube preattached to a 10C ring control syringe. 3 per box....
Medicine Products: