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Amicus Therapeutics Announces Closing of $18.5 Million Registered Direct Offering of Common Stock
Date:3/2/2010

As previously announced, Amicus intends to use the net proceeds from the offering for general corporate purposes and to further advance the development of the Company's lead product candidate, Amigal™(migalastat HCl), including the initiation of the Phase 3 study to support registration in the European Union and the completion of certain activities required for the submission of a license application globally.

The shares and warrants described above were offered by Amicus pursuant to a registration statement previously filed and declared effective by the Securities and Exchange Commission.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy any of the securities described herein, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. Copies of the prospectus supplement and accompanying base prospectus relating to this offering may be obtained at the SEC's website at http://www.sec.gov or by calling Leerink Swann, toll free, at 1-800-808-7525, Ext. 4814.


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