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Amgen's Second Quarter 2012 Revenues Increased 13 Percent To $4.5 Billion And Adjusted Earnings Per Share (EPS) Increased 34 Percent To $1.83

the impact of stock option expense for the three and six months ended June 30, 2012 and 2011 was as follows: Three months endedSix months ended June 30, June 30, 2012201120122011"Adjusted" diluted EPS, excluding stock option expense

2.71Impact of stock option expense (net of tax)

(0.01)(0.02)(0.03)(0.04)"Adjusted" diluted EPS, including stock option expense

2.67(b)The tax effect of the adjustments between our GAAP and "Adjusted" results takes into account the tax treatment and related tax rate(s) that apply to each adjustment in the applicable tax jurisdiction(s). Generally, this results in a tax impact at the U.S. marginal tax rate for certain adjustments, including amortization of intangible assets and non-cash interest expense associated with our convertible notes, whereas the tax impact of other adjustments, including stock option expense, depends on whether the amounts are deductible in the tax jurisdictions where the expenses are incurred or the asset is located and the applicable tax rate(s) in those jurisdictions. Due to these factors, the effective tax rates for the adjustments to our GAAP income before income taxes, for the three and six months ended June 30, 2012 and 2011 were 32.9% and 33.8% and 35.1% and 33.4%, respectively. Amgen Inc.Reconciliation of GAAP Debt Outstanding to "Adjusted" Debt Outstanding(In millions)(Unaudited)GAAPAdjustments for


standard (a)"Adjusted"June 30, 2011$
4,151June 30, 2012$

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