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Amgen’s Fourth Quarter 2010 Adjusted Earnings Per Share Increased 11 Percent to $1.17; Full Year 2010 Adjusted Earnings Per Share Increased 6 Percent to $5.21
Date:1/24/2011

198 million unfavorable impact due to U.S. Health Care Reform.  International product sales increased 6 percent to $3,406 million in 2010 versus $3,216 million in the prior year.  Foreign exchange had no material impact on sales for the year.

Worldwide Aranesp® (darbepoetin alfa) sales decreased 2 percent to $633 million in the fourth quarter of 2010 versus $648 million in the fourth quarter of 2009.   U.S. Aranesp sales decreased 1 percent to $285 million in the fourth quarter of 2010 versus $288 million in the fourth quarter of 2009, due principally to a high-teens percentage point decrease in unit demand reflecting an overall decline in the segment. The decrease was substantially offset by favorable changes in wholesaler inventories and certain changes in accounting estimates.  International Aranesp sales decreased 3 percent to $348 million in the fourth quarter of 2010 versus $360 million in the fourth quarter of 2009 primarily due to foreign exchange.  Excluding the impact of foreign exchange, international Aranesp sales decreased 1 percent.  For the year, worldwide Aranesp sales decreased 6 percent to $2,486 million in 2010 versus $2,652 million in 2009, due principally to a mid-teens percentage point decline in U.S. unit demand.

EPOGEN® (Epoetin alfa) sales decreased 16 percent to $591 million in the fourth quarter of 2010 versus $703 million in the fourth quarter of 2009, due primarily to a high single-digit percentage point decline in unit demand and, to a lesser extent, unfavorable changes in wholesaler inventories and accounting estimates. The decrease in unit demand partially reflects a decrease in dose utilization as healthcare providers began implementing new dose regimens, partially offset by patient population growth.  For the year, EPOGEN sales decreased 2 percent to $2,524 million in 2010 versus $2,569 million in 2009, due primarily to unit demand.

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