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Amgen’s Fourth Quarter 2010 Adjusted Earnings Per Share Increased 11 Percent to $1.17; Full Year 2010 Adjusted Earnings Per Share Increased 6 Percent to $5.21

>(*)Weighted-average shares for diluted EPS9469461,0111,012Diluted earnings per share$
.05Year endedYear endedDecember 31, 2010December 31, 2009GAAP"Adjusted" GAAP"Adjusted" Income (Numerator):Net income for basic and diluted EPS$
5,024$   4,605$
5,014Shares (Denominator):Weighted-average shares for basic EPS9609601,0161,016Effect of dilutive securities55


(*)Weighted-average shares for diluted EPS9659651,0211,021Diluted earnings per share$
4.91(*)Dilutive securities used to compute "Adjusted" diluted earnings per share for the three and twelve months ended December 31, 2010 and 2009 were computed under the treasury stock method assuming that we do not expense stock options. Amgen Inc.Product Sales Detail by Product and Geographic Region(In millions)(Unaudited)Three months endedYear endedDecember 31, December 31, 2010200920102009Aranesp® - U.S.$
,251Aranesp® - International3483601,3831,401EPOGEN® - U.S.5917032,5242,569Neulasta® - U.S.6826512,6542,527NEUPOGEN® - U.S.232229932901Neulasta® - International236225904828NEUPOGEN® - International8797354387Enbrel® - U.S.8758533,3043,283Enbrel® - Canada6459230210Sensipar® - U.S.115109459429Mimpara® - International7362255222Vectibix® - U.S.312511597Vectibix® - International4841173136Nplate® - U.S.342412978Nplate® - International311710032Prolia® - U.S.16-26-Prolia® - International4-7-XGEVA™ - U.S.8-8-Total product sales$

(a) 8613,406

(b) 3,216Total product sales$

(a) $

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