Navigation Links
Amgen and UCB Team Up With NASA on Final Space Shuttle Mission to Conduct Preclinical Test of Sclerostin Antibody on Bone Loss
Date:7/5/2011

Thousand Oaks, Calif. and BRUSSELS, July 5, 2011 /PRNewswire/ -- Amgen (NASDAQ: AMGN) and UCB (Euronext Brussels: UCB) announced today that they are collaborating with the National Aeronautics and Space Administration (NASA) Ames Research Center to conduct a preclinical test of a sclerostin antibody in an experiment that will take place aboard space shuttle Atlantis, on the final NASA shuttle mission, Space Shuttle Flight STS-135, scheduled to launch July 8, 2011.

The loss of bone mass during space flight remains a significant problem for human space missions, especially long-term flights. This experiment will assess the effect of a sclerostin antibody on the loss of bone associated with space flight in mice. In this experiment of 30 space-flown mice, half of the mice are given the sclerostin antibody and the remaining mice receive a placebo. After the flight, various aspects of the structure, composition, strength, and cell and molecular nature of the bones from the flight and ground-based control mice will be analyzed.

The sclerostin antibody is designed to inhibit the action of "sclerostin," a protein that is a key negative regulator of bone formation, bone mass, and bone strength. The findings may also provide insight into potential further research in the prevention and treatment of the skeletal fragility that can result from "skeletal disuse" in such conditions as immobilization, stroke, cerebral palsy, muscular dystrophy, spinal cord injury, and reduced physical activity.

"It is an honor to work with NASA on this historic final mission," said Chris Paszty, Ph.D., scientific executive director at Amgen. "This proof of principle study will enhance our understanding of the science behind the sclerostin antibody and arm us with important research to support potential future therapeutic applications in both astronauts and patients suffering from bone loss."'/>"/>

SOURCE Amgen
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Arthritis Foundation Announces Amgen and Wyeth to Be Presenting Sponsor of the 2008 Arthritis Walk (R)
2. Medarex to Receive Milestone Payment from Amgen
3. AMT Obtains License to Amgens GDNF Gene to Develop Treatment for Parkinsons Disease with AMTs Proprietary Gene Therapy Platform
4. Amgen, Takeda and Millennium Provide Update on Phase 3 Trial of Motesanib in Patients With Non-Small Cell Lung Cancer
5. CDC Foundation Partners with Amgen, CDC to Reduce Infections Among Cancer Patients
6. Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)
7. Amgen Issues Statement on Outcomes of Advisory Committee for Reproductive Health Drugs (ACRHD) Meeting
8. Amgen Announces Top-Line Results of Trial to Reduce Cardiovascular Events With Aranesp(R) Therapy (TREAT) in CKD Patients With Type-2 Diabetes
9. Amgen Presents Data From First Nplate(R) Study in Children With Chronic ITP
10. Amgen Highlights Data to be Presented at American Society for Bone and Mineral Research (ASBMR) Meeting
11. Amgen Board Authorizes $5 Billion Increase in Stock Repurchase Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... 29, 2014   Mast Therapeutics, Inc. ... today that Santosh Vetticaden, Chief Medical Officer and ... for personal reasons, in mid-September.  Edwin L. ... Aires Pharmaceuticals, which Mast acquired earlier this year, ... Company,s interim Chief Medical Officer.  Dr. Parsley previously ...
(Date:8/29/2014)... Thoratec Corporation (NASDAQ: THOR ), ... to save, support and restore failing hearts, said today ... Global Healthcare Conference on Wednesday, September 10. ... Officer, will provide an update on the company, beginning ... Daylight Time).   A webcast of the ...
(Date:8/29/2014)... , Aug. 29, 2014 Research and ... "China Orthopedic Instrument Industry Report, 2014-2017" report to ... population and rising proportion of reimbursement for medical expenses, ... released, with its scale presenting a CAGR of 19.2% ... are three product segments of orthopedic instruments in ...
Breaking Medicine Technology:Mast Therapeutics Announces Management Change 2Mast Therapeutics Announces Management Change 3Mast Therapeutics Announces Management Change 4China Orthopedic Instrument Industry Report, 2014-2017 2
(Date:8/30/2014)... (PRWEB) August 30, 2014 RB SEO ... cost SEO service for small businesses. , RBSEO Services ... cannot afford costly search engine optimization service. So, the ... small businesses into account. , On being asked ... have introduced this low cost SEO service because many ...
(Date:8/30/2014)... After offering hyperbaric oxygen therapy treatments ... several years, Dr. Roy Schmidt and the staff ... scholarship program for veterans who have been diagnosed ... this summer to discuss veterans’ needs ( http://www.prweb.com/releases/2014/06/prweb11954058.htm ... light on the large number of veterans who ...
(Date:8/30/2014)... Seniors Guide, the comprehensive guide to all things ... Alzheimer’s Disease, Dementia, and Memory Loss . , Country singer ... diagnosed with the Alzheimer’s, inspired Seniors Guide writers to review ... The movie, out on October 14, 2014, shows a glimpse ... the disease – which inspires a final tour from the ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 Continuing to ... Dermatology is expanding with the addition of a new ... Hammond who has provided leading-edge skin care in Grand ... Dermatology. , “As a doctor, my passion is ... Through partnering with Forefront Dermatology, I’m better able to ...
(Date:8/30/2014)... Hastings and Hastings, a qualified team of ... is pleased to report having saved a client $67,100 ... many cases where Hastings and Hastings has tailored its ... greater portion of their settlement or recovery. The firm ... solution for Arizona car accident victims is achievable through ...
Breaking Medicine News(10 mins):Health News:RBSEO Services Introduces Low Cost SEO Service for Small Businesses 2Health News:Tennessee Hyperbaric Center Offering HBOT Scholarships to Veterans 2Health News:Alzheimer’s Disease and Dementia Focus on Retirement Website SeniorsGuideOnline.com 2Health News:Expanding Care at the Forefront of Dermatology 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2
... Companies, Inc. (NYSE: PRX ) announced today that it ... 3, 2009 at 9:00 am EST to review results for the ... will release results after the market closes on Monday, March 2, ... website at www.parpharm.com .Access to the live webcast can be ...
... say , , WEDNESDAY, Feb. 25 (HealthDay News) -- University of ... that gives chili peppers their fiery flavor, also works to ... Tuesday in the journal PLoS Biology , researchers found ... and heat. , "The receptor acts like a gate to ...
... who have more years of fertility (the time from ... developing Parkinsons disease than women with fewer years, according ... Einstein College of Medicine of Yeshiva University., , These ... to the bodys own, or endogenous, hormones, including estrogen, ...
... One Reform, Medicare for All, Will Solve Crisis and ... largest organization of registered nurses today praised President Obama,s ... Congress Tuesday night, but emphasized that only genuine reform, ... solve the crisis -- and rein in the skyrocketing ...
... scientific data , , WEDNESDAY, Feb. 25 (HealthDay News) -- ... any new drug applications from a Ranbaxy Laboratories plant ... data. , Ranbaxy, based in India, is one of ... States. , "We took this action after it ...
... GURGAON, India, Feb. 25 Ranbaxy has just received ... approved ANDAs from Ranbaxy,s Paonta Sahib facility have been ... "Application Integrity Policy" or "AIP". Ranbaxy will analyze ... in a timely manner.The FDA has said it has ...
Cached Medicine News:Health News:Naturally produced estrogen may protect women from Parkinson's disease 2Health News:Nurses Welcome President's Call for Comprehensive Health Reform 2Health News:FDA Halts New Applications From Indian Drug Maker's Plant 2Health News:Press Statement Issued by Ranbaxy Laboratories Limited 2
... and 8 Suction Catheters With Contro-Vac Valve ... for Low-Risk Respiratory Suctioning, ,Medline's 6 ... and DeLee Tips are the optimal tools ... utilizes a forward placed suction valve to ...
... Catheters are available in ... atraumatic DeLee tip with staggered ... tip. Two types of catheter ... deliver easy fingertip control with ...
... Tri-Flo® suction catheter design was created ... patients while still providing high suctioning ... (5/6, 8 or 10 Fr) feature ... catheter placement. Our complete catheter line ...
Tracheal Suction Latex Rubber Catheters - DeLee Tip...
Medicine Products: