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Amgen To Present Data From Four Phase 2 Studies At Upcoming American Heart Association Scientific Sessions 2012
Date:11/2/2012

THOUSAND OAKS, Calif., Nov. 2, 2012 /PRNewswire/ -- Amgen (NASDAQ: AMGN) will present data from four Phase 2 trials of AMG 145, an investigational fully human monoclonal antibody directed against PCSK9, a protein that reduces the liver's ability to remove low density lipoprotein cholesterol (LDL-C), or "bad" cholesterol from the blood, at the upcoming American Heart Association (AHA) Scientific Sessions 2012.

Selected abstracts of interest that will be presented at the meeting include:

  • Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD): Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial
    Late-Breaking Clinical Trials, Monday, Nov. 05, 10:50 a.m. – 11:00 a.m. (Hall G)

  • Goal Achievement after Utilizing an Anti-PCSK9 in Statin Intolerant Subjects (GAUSS): Results from a Randomized, Double-blind, Placebo controlled Study
    Late-Breaking Clinical Trials, Monday, Nov. 05, 11:00 a.m. – 11:10 a.m.  (Hall G)

  • LAPLACE-TIMI 57 Primary Results
    Clinical Science: Special Reports, Tuesday, Nov. 06, 7:45 a.m. – 7:55 a.m.  (Petree Hall D)

  • Efficacy and Safety of a Fully Human Monoclonal Antibody Against PCSK9 as Monotherapy for Hypercholesterolemia: Results from the MENDEL Study, a Global Phase 2 Trial of AMG 145
    Clinical Science: Special Reports, Tuesday, Nov. 06, 7:55 a.m. – 8:05 a.m.  (Petree Hall D)

About Amgen

Amgen discovers, develops, manufactures and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science's promise by bringing safe, effective medicines from lab to manufacturing plant to patient. Amgen therapeutics ha
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