Navigation Links
Amgen To Acquire Onyx Pharmaceuticals For $125 Per Share In Cash
Date:8/25/2013

cally advanced or metastatic HER2 negative breast cancer. Nexavar has also been submitted for U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) approval for the treatment of radioactive iodine-refractory differentiated thyroid cancer.  Nexavar is co-developed by Onyx and Bayer except in Japan where Bayer manages all development. The companies co-promote Nexavar in the U.S. Outside of the U.S., Bayer has exclusive marketing rights, and Bayer and Onyx share profits globally, excluding Japan.
  • Stivarga® (regorafenib) tablets is Bayer's oral multiple kinase inhibitor, currently approved in the U.S. for the treatment of patients with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if KRAS wild type, an anti-EGFR therapy. It is also indicated for the treatment of patients with locally advanced, unresectable or metastatic gastrointestinal stromal tumor (GIST) who have been previously treated with imatinib mesylate and sunitinib malate. Stivarga is a Bayer compound developed by Bayer and jointly promoted by Bayer and Onyx in the U.S. In 2011, Bayer entered into an agreement with Onyx, under which Onyx receives a 20 percent royalty on all global net sales of Stivarga in oncology.
  • Palbociclib is Pfizer's investigational oral, small molecule cyclin-dependent kinase 4/6 inhibitor being developed by Pfizer in a Phase 3 trial for ER+, HER2-negative advanced breast cancer.  Palbociclib has received Breakthrough Therapy designation by the U.S. FDA based on preliminary Phase 2 data showing improvement in median progression-free survival in combination therapy.  Onyx will receive an 8 percent royalty on future worldwide sales of palbociclib.  
  • Financing and Approvals
    Amgen will finance the acquisition with $8.1 billion in c
    '/>"/>

    SOURCE Amgen
    Copyright©2012 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21

    Related medicine technology :

    1. Amgen to Acquire Mustafa Nevzat, a Leading Privately Held Turkish Pharmaceutical Company
    2. Four Californians Selected As Breakaway from Cancer® Champions To Be Honored During Amgen Tour of California
    3. Amgen to Present at the Baird Growth Stock Conference
    4. Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars
    5. Amgens BiTE® Antibody Blinatumomab (AMG 103) Achieved High Rate of Complete Response in Adult Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
    6. Amgen Announces Top-Line Results Of Phase 3 Sensipar®/Mimpara® EVOLVE™ Trial
    7. Amgen Completes Acquisition of Mustafa Nevzat Pharmaceuticals
    8. Amgen Completes Acquisition of KAI Pharmaceuticals
    9. Amgens Second Quarter 2012 Revenues Increased 13 Percent To $4.5 Billion And Adjusted Earnings Per Share (EPS) Increased 34 Percent To $1.83
    10. Amgen Announces Termination Of Ganitumab Phase 3 Study For Futility In Metastatic Pancreatic Cancer
    11. Amgen To Present At The Baird Healthcare Conference
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/29/2014)... SALT LAKE CITY , July 29, 2014 /PRNewswire/ ... at The Grand American Hotel in Salt ... keynote speakers representing some of most respected healthcare organizations ... Health Catalyst , is an industry conference devoted ... of healthcare analytics,  an essential element of both accountable ...
    (Date:7/29/2014)...  Novation, a VHA and UHC company, today ... features that automate key health care supply chain ... Association.  The new and enhanced ... Value Analysis, Item Master and Formulary – are ... most critical challenges brought on by health care ...
    (Date:7/29/2014)...   Abide Therapeutics announced today the ... board of directors. Thornberry was previously senior vice ... Merck & Co. Inc., where she led discovery, ... diabetes, osteoporosis, fertility and contraception. Thornberry, a distinguished ... resulted in the discovery of Januvia TM , ...
    Breaking Medicine Technology:Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 2Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 3Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 4Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 5Breakthrough Novation Applications Empower Children's Hospital Association Members to Lower Costs, Increase Quality 2Breakthrough Novation Applications Empower Children's Hospital Association Members to Lower Costs, Increase Quality 3Breakthrough Novation Applications Empower Children's Hospital Association Members to Lower Costs, Increase Quality 4Breakthrough Novation Applications Empower Children's Hospital Association Members to Lower Costs, Increase Quality 5Abide Therapeutics Appoints Nancy Thornberry to Board of Directors 2Abide Therapeutics Appoints Nancy Thornberry to Board of Directors 3
    ... is accepting applications for the ... or pre-clinical research focused on human protein therapies in ... The application deadline is April 1, 2011. ... protein products manufacturers in the world, launched the Octapharma ...
    ... 14 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. (Nasdaq: ... an emerging leader in the development, assembly, marketing ... products in China, today announced that on October ... at the China International Medical Equipment Fair ("CMEF") ...
    Cached Medicine Technology:Octapharma Accepting Applications for Research Grants Focused on Human Protein Therapies 2Dehaier Medical Shows New Products at 2010 China International Medical Equipment Fair 2Dehaier Medical Shows New Products at 2010 China International Medical Equipment Fair 3
    (Date:7/29/2014)... July 29, 2014 For numerous women from ... relationship work can turn out being quite hard. Well, the ... he discovered the method that can help all these women. ... make a guy show love and attention every day. ... method was actually created by Alex Carter who published a ...
    (Date:7/29/2014)... (PRWEB) July 29, 2014 DailyGossip.org reveals in ... developed by someone who can perfectly understand patients and what ... , Ellie Gadsby is the author of the new ... years. After years of suffering, Ellie started her very own ... of remedies. , The author of the Get Rid of ...
    (Date:7/29/2014)... Denver, Colorado (PRWEB) July 29, 2014 ... review that the program was actually created by a ... vitiligo, too. He tried numerous treatments for this disorder, ... Dawson found himself in the situation of having to ... after years of research. Dawson used this method, too, ...
    (Date:7/29/2014)... severe combat injuries threatening more than one limb, reconstructive ... of safety and effectiveness in avoiding amputation, reports a ... and Reconstructive Surgery , the official medical journal ... (ASPS). , Experience with multiple limb salvage procedures in ... rates, with no increase in complications compared to single-flap ...
    (Date:7/29/2014)... Although the bite of a brown recluse spider is ... an expert notes. It,s still important to recognize ... brown recluse spider bite, warned Dr. Donna Seger, medical ... potentially dangerous bites are on the rise. "As ... The [bite] has classic characteristics, but if physicians are ...
    Breaking Medicine News(10 mins):Health News:"Make Him Desire You" Review Reveals Unique Formula to Make Men Feel a Special Kind of Love 2Health News:Get Rid of Cold Sores Fast Review Exposes the Way to Stop Outbreaks 2Health News:Natural Vitiligo Treatment System Review Reveals Michael Dawson’s New Vitiligo Cure Program 2Health News:Good outcomes with multiple limb salvage after severe combat injuries, reports Plastic and Reconstructive Surgery 2Health News:Brown Recluse Spider Bites on the Rise, Expert Warns 2
    ... June 24 American Life League executive director Shaun ... mothers will be referred for abortions by Caritas Christi, ... with CeltiCare goes into effect July 1. , ... ) , , "Caritas Christi and the ...
    ... to storing memories , WEDNESDAY, June 24 (HealthDay News) ... essential for long-term storage of memories. , Their study ... while asleep remember them less well than mice who ... for Neural Circuit Genetics at MITs Picower Institute for ...
    ... Olaparib prevents malignant cells from repairing themselves, researchers say ... A new cancer drug called olaparib worked well in ... cancers in individuals who were genetically vulnerable to developing ... gene mutations are susceptible to developing breast and ovarian ...
    ... now enables trusted access for patients with the Anakam ... Anakam announced today that Sharp HealthCare, San Diego ... Suite(R) to enable trusted access for patients accessing Sharp,s ... excellent healthcare service to meet the needs of its ...
    ... June 24 Cardiogenesis Corporation (Pink Sheets: CGCP), a ... that Paul J. McCormick has been appointed as Executive ... 1st. As Executive Chairman, Mr. McCormick will have ... execution, financing, and investor relations. In addition the ...
    ... , WASHINGTON, June 24 The following are remarks as ... Heat Press Conference on Detroit Takedown: , , Good ... today by my colleagues, Department of Health and Human Services ... , Just a few weeks ago, Secretary Sebelius and ...
    Cached Medicine News:Health News:A.L.L. Promises Caritas Christi Investigation After July 1 2Health News:A.L.L. Promises Caritas Christi Investigation After July 1 3Health News:Sleep May Be Essential for Long-Term Memory 2Health News:New Cancer Drug Fights Tumors in Those With BRCA Mutations 2Health News:New Cancer Drug Fights Tumors in Those With BRCA Mutations 3Health News:Sharp HealthCare and Anakam(R) Partner to Protect Patients' Health Information 2Health News:Sharp HealthCare and Anakam(R) Partner to Protect Patients' Health Information 3Health News:Cardiogenesis Corporation Names Paul J. McCormick Executive Chairman 2Health News:Cardiogenesis Corporation Names Paul J. McCormick Executive Chairman 3Health News:Remarks As Prepared for Delivery by Attorney General Eric Holder at the Heat Press Conference on Detroit Takedown 2Health News:Remarks As Prepared for Delivery by Attorney General Eric Holder at the Heat Press Conference on Detroit Takedown 3
    ... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
    Medicine Products: