Navigation Links
Amgen Recognized for Best Pipeline and Best New Drug at Scrip Awards
Date:11/23/2009

ion of existing hematopoietic malignancies or MDS, and effects on red and white blood cells are all potential risks associated with romiplostim treatment. As with all therapeutic proteins, patients may develop antibodies to the therapeutic protein.

About Denosumab

In February 2009, the U.S. Food and Drug Administration (FDA) accepted the Biologic License Applications (BLA), submitted by Amgen for Prolia(TM) (denosumab) for the treatment and prevention of osteoporosis in postmenopausal women and treatment and prevention of bone loss in women and men receiving hormone therapy for either breast cancer or prostate cancer. On October 2009, the FDA issued Complete Response Letters for the BLA application for denosumab requesting additional information needed to complete the review of the applications for approval, including updated safety data. The FDA also requested a new clinical program to support approval of denosumab for the prevention of PMO and additional adequate and well-controlled clinical trials demonstrating the denosumab has no detrimental effects on either time-to disease progression or overall survival for cancer treatment-induced bone loss (in breast cancer and prostate cancer patients).

Denosumab is the first fully human monoclonal antibody in late stage clinical development that specifically targets RANK Ligand, an essential regulator of osteoclasts (the cells that break down bone). Denosumab is being investigated for its potential to inhibit all stages of osteoclast activity through a targeted mechanism. It is being studied in a range of other bone loss conditions including rheumatoid arthritis, and cancer treatment-induced bone loss (in breast cancer and prostate cancer patients), as well as for its potential to delay bone metastases and inhibit and treat bone destruction across many stages of cancer.

About Amgen

Amgen discovers, develops, manufactures and delivers innovative human
'/>"/>

Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Arthritis Foundation Announces Amgen and Wyeth to Be Presenting Sponsor of the 2008 Arthritis Walk (R)
2. Medarex to Receive Milestone Payment from Amgen
3. AMT Obtains License to Amgens GDNF Gene to Develop Treatment for Parkinsons Disease with AMTs Proprietary Gene Therapy Platform
4. Amgen, Takeda and Millennium Provide Update on Phase 3 Trial of Motesanib in Patients With Non-Small Cell Lung Cancer
5. CDC Foundation Partners with Amgen, CDC to Reduce Infections Among Cancer Patients
6. Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)
7. Amgen Issues Statement on Outcomes of Advisory Committee for Reproductive Health Drugs (ACRHD) Meeting
8. Amgen Announces Top-Line Results of Trial to Reduce Cardiovascular Events With Aranesp(R) Therapy (TREAT) in CKD Patients With Type-2 Diabetes
9. Amgen Highlights Data to be Presented at American Society for Bone and Mineral Research (ASBMR) Meeting
10. Call for Applications: The Amgen Award for Science Teaching Excellence
11. Amgen Announces Overall Survival Results for Vectibix(R) in First-Line Metastatic Colorectal Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... FRESH MEADOWS, N.Y. , Dec. 15, 2014 /PRNewswire/ ... using the SPL (Structured Product Labeling) markup language standard, ... need the understanding and skills to work with the ... present a series of three webinars on the benefits ... The three one-hour webinars will be facilitated by ...
(Date:12/14/2014)... 14, 2014  ChartSpan, a consumer platform for patients ... and iPad medical app in the United ... ChartSpan is an iPhone and ... manage and send electronic healthcare records. The product was ... tired of waiting for the healthcare system to deliver ...
(Date:12/13/2014)... 12, 2014 Mindray Medical International Limited ("Mindray", ... and marketer of medical devices worldwide, today announced shareholder ... held in Hong Kong on ... shareholders voted to re-elect incumbent directors Li Xiting and ... shareholders did not re-elect Peter Wan as ...
Breaking Medicine Technology:Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3ChartSpan Becomes The Most Downloaded Medical App in America 2ChartSpan Becomes The Most Downloaded Medical App in America 3Mindray Announced Shareholder Resolutions Post 2014 Annual General Meeting 2
... CITY, Calif., April 16, 2007 /PRNewswire-FirstCall/ --,Threshold ... its oncology pipeline, which includes two,preclinical presentations ... research presentations from Threshold's Tubulin,Inhibitor program. The ... Association for Cancer Research (AACR) annual meeting,being ...
... Trial to 9 mg Dosage,Level, HOPKINTON, Mass., April ... that clinical data on its lead,nerve repair therapy, ... Scientific Session at the 75th Annual Meeting of,the ... , The oral presentation, "Results of the Cethrin ...
Cached Medicine Technology:Threshold Pharmaceuticals Announces Multiple Presentations on,Oncology Pipeline at the 2007 American Association for Cancer,Research (AACR) Annual Meeting 2Threshold Pharmaceuticals Announces Multiple Presentations on,Oncology Pipeline at the 2007 American Association for Cancer,Research (AACR) Annual Meeting 3Boston Life Sciences, Inc. Announces Presentation of Cethrin Phase,I/IIa 6-Month Results at 75th Annual Meeting of the American,Association of Neurological Surgeons 2Boston Life Sciences, Inc. Announces Presentation of Cethrin Phase,I/IIa 6-Month Results at 75th Annual Meeting of the American,Association of Neurological Surgeons 3Boston Life Sciences, Inc. Announces Presentation of Cethrin Phase,I/IIa 6-Month Results at 75th Annual Meeting of the American,Association of Neurological Surgeons 4
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... health director Margaret Chan Tuesday emerged as favourite to ... (WHO). // ,The 60-year-old obstetrician, who led Hong ... shortlist of candidates released overnight ahead of a final ... 32 votes in the first round of voting Monday ...
... of the most common diseases seen among pediatric practices ... bacterial diseases //and usually treated with antibiotics. But ... December and which is currently available online, provides evidences ... the treatment complicated. ,The researchers used a ...
... rage may reveal much more than what meets the eye, thought ... lead to abusive and unbecoming behavior, akin to a dormant volcano ... of steroid abuse on patients, with a view to gauging the ... abuse of steroids is often lined to the use of weapons ...
... a study of Australian cervical cancer rates, there is a pressing ... the causative virus and tests for its detection need to be ... recommended to get Pap smear tests done once in 2 years. ... can be increased to 3 as in the U.K. without any ...
... Mittal has strengthened his grip on Arcelor Mittal, announcing Monday ... world's largest steel maker//. ,The move reverses a ... the post of chief of the combined group, shortly after ... with 56-year-old Mittal's giant Mittal Steel. ,But in ...
... appointments after hours with a nurse or primary care physician ... difficult than in several other countries// according to a study ... in seven countries revealed that they had arrangements for after-hours ... in New Zealand, 87 percent in the United Kingdom, 76 ...
Cached Medicine News:Health News:The need to revamp cervical cancer prevention programs 2Health News:Health Care in America-Not a Rosy Picture 2
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
The BioCheck LH ELISA is intended for the quantitative determination of luteinizing hormone (LH) in human serum. This assay is useful in the diagnosis and treatment of gonadal dysfunction....
... (LH) is a glycoprotein secreted by the ... and TSH, the intact LH molecule is ... These glycoproteins all have homologous alpha-subunits, however ... LH and FSH production and secretion are ...
The NPT7 blood gas analyzer measures pH/blood gases and oximetry on 90 L sample volume with a two-step sampling procedure. Clinical tests compare NPT7 accuracy to that of benchtop analyzers. 30 sampl...
Medicine Products: