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Amgen Highlights Data to be Presented at American Society for Bone and Mineral Research (ASBMR) Meeting
Date:9/10/2009

THOUSAND OAKS, Calif., Sept. 10 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN) today announced that new data will be presented on the burden of osteoporosis, current osteoporosis treatment challenges and Prolia(TM) (denosumab) at the 2009 American Society for Bone and Mineral Research (ASBMR) annual meeting in Denver from Sept. 11-15, 2009. Prolia currently is being evaluated by regulatory bodies in the United States (U.S.), the European Union, Switzerland, Australia and Canada as a potential therapy for postmenopausal osteoporosis and bone loss in patients undergoing hormone ablation for prostate and breast cancer.

"The continued need for new alternatives to treat postmenopausal osteoporosis is reinforced by data that will be presented at this year's ASBMR meeting. These data highlight challenges with adherence to therapy and show the link between adherence and fracture outcomes," said Roger M. Perlmutter, M.D., Ph.D., executive vice president for Research and Development at Amgen. "Clinical data that will be presented at the meeting include a Phase 3 study sub-analysis showing Prolia's effect on fracture reduction in woman at a greater risk for fracture, 6-year efficacy and safety data from a Phase 2 study, and bone histology data."

ASBMR abstracts are available and can be viewed online at www.asbmr.org. Identified below are selected abstracts of interest on Amgen research.

Prolia(TM) (denosumab)

-- Effects of Denosumab on Bone Mineral Density and Biochemical Markers of Bone Turnover: 6 Year Results of a Phase 2 Clinical Trial

Lead Author: Miller P

Abstract No. 1026 (Saturday, Sept. 12, 2009, 10:15am MT)

-- Effects of Denosumab on Bone Histomorphometry: the FREEDOM and STAND Studies Lead Author: Re
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SOURCE Amgen
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