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Amgen Highlights Data To Be Presented At American Society of Clinical Oncology Annual Meeting
Date:5/15/2013

in pediatric patients with acute lymphoblastic leukemia (ALL) will be presented for blinatumomab, the first of a new investigational class of agents designed to harness the body's cytotoxic T cells to kill cancer cells.

  • Cytological and Molecular Remissions With Blinatumomab Treatment in Second or Later Bone Marrow Relapse in Pediatric Acute Lymphoblastic Leukemia (ALL)
    Abstract No. 10007, Oral Presentation, Sunday, June 2, 10:30 a.m. CDT, S504

Vectibix® (panitumumab)
Three new analyses of trials studying Vectibix in combination with FOLFOX, an oxaliplatin-based chemotherapy, as a first-line treatment for metastatic colorectal cancer (mCRC) will be presented. Presentations include two analyses of the Phase 3 PRIME ('203) trial: an updated overall survival analysis and an analysis of the treatment effect by RAS/RAF status, respectively. The Phase 3 PRIME ('203) trial evaluated Vectibix plus FOLFOX versus FOLFOX alone in patients with wild-type KRAS mCRC. An analysis by RAS status of the Phase 2 PEAK ('509) trial comparing the efficacy of Vectibix in combination with FOLFOX to the efficacy of bevacizumab in combination with FOLFOX in patients with wild-type KRAS mCRC will also be presented.

  • Overall Survival (OS) Analysis from PRIME: Randomized Phase 3 Study of panitumumab (pmab) with FOLFOX4 for First-line Metastatic Colorectal Cancer (mCRC)
    Abstract No. 3620, Poster, Sunday, June 2, 8:00 a.m. CDT, S Hall A2
  • Analysis of KRAS/NRAS Mutations in PEAK: A Randomized Phase II Study of FOLFOX6 plus Panitumumab (pmab) or Bevacizumab (bev) as First-line Treatment (tx) for Wild-type (WT) KRAS (exon 2) Metastatic Colorectal Cancer (mCRC)
    Abstract No. 3631, Poster, Sunday, June 2, 8:00 a.m. CDT, S Hall A2
  • Analysis of KRAS/NRAS and BRAF M
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